A newly described coronavirus named severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has …

Arthropod-borne viruses pose a major threat to global public health. Thus, innovative
strategies for their control and prevention are urgently needed. Here, we exploit the natural …

Some viruses use phosphatidylinositol phosphate (PIP) to mark membranes used for
genome replication or virion assembly. PIP-binding motifs of cellular proteins do not exist in …

RNA recombination in positive-strand RNA viruses is a molecular-genetic process, which
permits the greatest evolution of the genome and may be essential to stabilizing the genome …

Viral RNA-dependent RNA polymerases (RdRps) are a target for broad-spectrum antiviral
therapeutic agents. Recently, we demonstrated that incorporation of the T-1106 …

Phosphoinositides and phosphoinositide binding proteins play a critical role in membrane
and protein trafficking in eukaryotes. Their critical role in replication of cytoplasmic viruses …

Numerous cellular proteins interact with membrane surfaces to affect essential cellular
processes. These interactions can be directed towards a specific lipid component within a …

The main aims of the present study were to design a fusion protein of Leishmania major
stress-inducible protein 1 (LmSTI1) and Phlebotomus papatasi SP15 (PpSP15), and to …

How viral proteins are targeted specifically to sites of genome replication is a longstanding
question in virology. All positive-strand RNA viruses reorganize host intracellular …

Patients with dysphagia diseases require food with acceptable textural characteristics.
Additionally, due to the consumption of smaller portions, these patients receive insufficient …