Cross-talk between different types of post-translational modifications on the same protein
molecule adds specificity and combinatorial logic to signal processing, but it has not been …

Protein phosphorylation serves as a primary mechanism of signal transduction in the cells of
biological organisms. Technical advancements over the last several years in mass …

A newly described coronavirus named severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has …

Electron-transfer dissociation (ETD) delivers the unique attributes of electron capture
dissociation to mass spectrometers that utilize radio frequency trapping-type devices (eg …

Large-scale protein sequencing methods rely on enzymatic digestion of complex protein
mixtures to generate a collection of peptides for mass spectrometric analysis. Here we …

Mass spectrometry has become a key technology for modern large-scale protein
sequencing. Tandem mass spectrometry, the process of peptide ion dissociation followed by …

The causative agent of the coronavirus disease 2019 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed …

The emergence of SARS-CoV-2 variants of concern suggests viral adaptation to enhance
human-to-human transmission,. Although much effort has focused on the characterization of …

Protein phosphorylation is central to the understanding of cellular signaling, and cellular
signaling is suggested to play a major role in the regulation of human embryonic stem (ES) …

INTRODUCTION The emergence of three lethal coronaviruses in< 20 years and the urgency
of the COVID-19 pandemic have prompted efforts to develop new therapeutic strategies …