Molecular targeted therapy: Treating cancer with specificity
Molecular targeted therapies are revolutionized therapeutics which interfere with specific
molecules to block cancer growth, progression, and metastasis. Many molecular targeted …
molecules to block cancer growth, progression, and metastasis. Many molecular targeted …
Metallic powder-bed based 3D printing of cellular scaffolds for orthopaedic implants: A state-of-the-art review on manufacturing, topological design, mechanical …
Metallic cellular scaffold is one of the best choices for orthopaedic implants as a
replacement of human body parts, which could improve life quality and increase longevity …
replacement of human body parts, which could improve life quality and increase longevity …
[HTML][HTML] Benzimidazole and its derivatives as cancer therapeutics: The potential role from traditional to precision medicine
Cancer is the second leading cause of mortality globally which remains a continuing threat
to human health today. Drug insensitivity and resistance are critical hurdles in cancer …
to human health today. Drug insensitivity and resistance are critical hurdles in cancer …
SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls
Memory T cells induced by previous pathogens can shape susceptibility to, and the clinical
severity of, subsequent infections. Little is known about the presence in humans of pre …
severity of, subsequent infections. Little is known about the presence in humans of pre …
A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2–spike protein–protein interaction
A robust serological test to detect neutralizing antibodies to SARS-CoV-2 is urgently needed
to determine not only the infection rate, herd immunity and predicted humoral protection, but …
to determine not only the infection rate, herd immunity and predicted humoral protection, but …
Induction of Apoptosis by the Severe Acute Respiratory Syndrome Coronavirus 7a Protein Is Dependent on Its Interaction with the Bcl-XL Protein
YX Tan, THP Tan, MJR Lee, PY Tham… - Journal of …, 2007 - Am Soc Microbiol
The severe acute respiratory syndrome coronavirus (SARS-CoV) 7a protein, which is not
expressed by other known coronaviruses, can induce apoptosis in various cell lines. In this …
expressed by other known coronaviruses, can induce apoptosis in various cell lines. In this …
Overexpression of 7a, a protein specifically encoded by the severe acute respiratory syndrome coronavirus, induces apoptosis via a caspase-dependent pathway
YJ Tan, BC Fielding, PY Goh, S Shen, THP Tan… - Journal of …, 2004 - Am Soc Microbiol
Besides genes that are homologous to proteins found in other coronaviruses, the severe
acute respiratory syndrome coronavirus genome also contains nine other potential open …
acute respiratory syndrome coronavirus genome also contains nine other potential open …
Graded microstructure and mechanical properties of additive manufactured Ti–6Al–4V via electron beam melting
Electron beam melting (EBM®)-built Ti–6Al–4V has increasingly shown great potential for
orthopedic implant and aerospace applications in recent years. The microstructure and …
orthopedic implant and aerospace applications in recent years. The microstructure and …
Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection
The efficacy of virus-specific T cells in clearing pathogens involves a fine balance between
antiviral and inflammatory features. SARS-CoV-2–specific T cells in individuals who clear …
antiviral and inflammatory features. SARS-CoV-2–specific T cells in individuals who clear …
Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection
Severe acute respiratory syndrome (SARS) is a highly contagious infectious disease which
first emerged in late 2002, caused by a then novel human coronavirus, SARS coronavirus …
first emerged in late 2002, caused by a then novel human coronavirus, SARS coronavirus …