A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has …
(SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has …
Chromatin sensing by the auxiliary domains of KDM5C regulates its demethylase activity and is disrupted by X-linked intellectual disability mutations
FS Ugur, MJS Kelly, DG Fujimori - Journal of molecular biology, 2023 - Elsevier
The H3K4me3 chromatin modification, a hallmark of promoters of actively transcribed genes,
is dynamically removed by the KDM5 family of histone demethylases. The KDM5 …
is dynamically removed by the KDM5 family of histone demethylases. The KDM5 …
Source of the fitness defect in rifamycin-resistant Mycobacterium tuberculosis RNA polymerase and the mechanism of compensation by mutations in the β′ subunit
Mycobacterium tuberculosis is a critical threat to human health due to the increased
prevalence of rifampin resistance (RMPr). Fitness defects have been observed in RMPr …
prevalence of rifampin resistance (RMPr). Fitness defects have been observed in RMPr …
Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance
Although the primary protein sequence of ubiquitin (Ub) is extremely stable over
evolutionary time, it is highly tolerant to mutation during selection experiments performed in …
evolutionary time, it is highly tolerant to mutation during selection experiments performed in …
Exploring the ligand preferences of the PHD1 domain of histone demethylase KDM5A reveals tolerance for modifications of the Q5 residue of histone 3
SE Anderson, JE Longbotham, PT O'Kane… - ACS chemical …, 2020 - ACS Publications
Understanding the ligand preferences of epigenetic reader domains enables identification of
modification states of chromatin with which these domains associate and can yield insight …
modification states of chromatin with which these domains associate and can yield insight …
Successful cryoablation of atrioventricular nodal reentrant tachycardia and coexisting accessory pathways without fluoroscopy
EE Gul, FS Ugur, C Akdeniz… - Congenital Heart …, 2013 - Wiley Online Library
We report the case of a 14‐year‐old boy patient admitted to our outpatient clinic with
palpitations and documented supraventricular tachycardia. Electrophysiological study and …
palpitations and documented supraventricular tachycardia. Electrophysiological study and …
[書籍][B] Domain regulation and mutational dysregulation of the histone demethylase KDM5C
FS Ugur - 2022 - search.proquest.com
The H3K4me3 chromatin modification, a hallmark of promoters of actively transcribed genes,
is dynamically removed by the KDM5 family of histone demethylases. The KDM5 …
is dynamically removed by the KDM5 family of histone demethylases. The KDM5 …
X-linked intellectual disability mutations alter the conformational state of a histone demethylase's sensing of chromatin
FS Ugur, MJS Kelly, DG Fujimori - bioRxiv, 2022 - biorxiv.org
The H3K4me3 chromatin modification, a hallmark of promoters of actively transcribed genes,
is dynamically removed by the KDM5 family of histone demethylases. The KDM5 …
is dynamically removed by the KDM5 family of histone demethylases. The KDM5 …
[引言][C] PP-276 SUCCESSFUL CRYOABLATION OF ATRIOVENTRICULAR NODAL REENTRANT TACHYCARDIA AND COEXISTING ACCESSORY PATHWAYS …
EE Gul, FS Ugur, C Akdeniz, V Tuzcu - International Journal of Cardiology, 2013 - infona.pl
PP-276 SUCCESSFUL CRYOABLATION OF ATRIOVENTRICULAR NODAL REENTRANT
TACHYCARDIA AND COEXISTING ACCESSORY PATHWAYS WITHOUT FLUOROSCOPY × …
TACHYCARDIA AND COEXISTING ACCESSORY PATHWAYS WITHOUT FLUOROSCOPY × …