Vision, choice, action and behavioural engagement arise from neuronal activity that may be
distributed across brain regions. Here we delineate the spatial distribution of neurons …

Correlates of sensory stimuli and motor actions are found in multiple cortical areas, but such
correlates do not indicate whether these areas are causally relevant to task performance …

Research in neuroscience increasingly relies on the mouse, a mammalian species that
affords unparalleled genetic tractability and brain atlases. Here, we introduce high-yield …

The striatum plays critical roles in visually-guided decision-making and receives dense
axonal projections from midbrain dopamine neurons. However, the roles of striatal …

The human motor system is remarkably proficient in the online control of visually guided
movements, adjusting to changes in the visual scene within 100 ms [1–3]. This is achieved …

Sensory decisions involve multiple cortical areas, but the specific roles of these areas are
not well understood. We trained head-fixed mice to discriminate visual contrast and report …

Sensory decisions involve multiple cortical areas, but it is unclear to what extent these areas
carry distinct signals and play distinct causal roles. We trained head-fixed mice to …

Behavior arises from neuronal activity, but it is not known how the active neurons are
distributed across brain regions and how their activity unfolds in time. Here, we used high …

Perceptual decisions involve a complex interaction of several brain areas. The neocortex is
thought to play a major role in this process, but it is unclear which cortical areas are causally …

When the two hands act together to achieve a goal, the redundancy of the system makes it
necessary to distribute the responsibility for error corrections across the two hands. In an …