與「"author:von Zastrow M"」相符的使用者個人學術檔案
![]() | Mark von ZastrowProfessor of Psychiatry and Pharmacology, UCSF 在 ucsf.edu 的電子郵件地址已通過驗證 被引用 42142 次 |
Endocytosis and signalling: intertwining molecular networks
A Sorkin, M Von Zastrow - Nature reviews Molecular cell biology, 2009 - nature.com
Cell signalling and endocytic membrane trafficking have traditionally been viewed as distinct
processes. Although our present understanding is incomplete and there are still great …
processes. Although our present understanding is incomplete and there are still great …
Signal transduction and endocytosis: close encounters of many kinds
A Sorkin, M Von Zastrow - Nature reviews Molecular cell biology, 2002 - nature.com
Binding of hormones, growth factors and other cell modulators to cell-surface receptors
triggers a complex array of signal-transduction events. The activation of many receptors also …
triggers a complex array of signal-transduction events. The activation of many receptors also …
Functional selectivity and classical concepts of quantitative pharmacology
The concept of intrinsic efficacy has been enshrined in pharmacology for half of a century,
yet recent data have revealed that many ligands can differentially activate signaling …
yet recent data have revealed that many ligands can differentially activate signaling …
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has …
(SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has …
Conformational biosensors reveal GPCR signalling from endosomes
R Irannejad, JC Tomshine, JR Tomshine, M Chevalier… - Nature, 2013 - nature.com
A long-held tenet of molecular pharmacology is that canonical signal transduction mediated
by G-protein-coupled receptor (GPCR) coupling to heterotrimeric G proteins is confined to …
by G-protein-coupled receptor (GPCR) coupling to heterotrimeric G proteins is confined to …
Control of synaptic strength by glial TNFα
Activity-dependent modulation of synaptic efficacy in the brain contributes to neural circuit
development and experience-dependent plasticity. Although glia are affected by activity and …
development and experience-dependent plasticity. Although glia are affected by activity and …
Ligand-regulated internalization and recycling of human beta 2-adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors.
M Von Zastrow, BK Kobilka - Journal of Biological Chemistry, 1992 - ASBMB
Agonist-regulated redistribution of human beta 2-adrenergic receptors was examined in 293
cells. A specific antiserum recognizing the carboxyl-terminal hydrophilic domain of the …
cells. A specific antiserum recognizing the carboxyl-terminal hydrophilic domain of the …
A kinase-regulated PDZ-domain interaction controls endocytic sorting of the β2-adrenergic receptor
TT Cao, HW Deacon, D Reczek, A Bretscher… - Nature, 1999 - nature.com
A fundamental question in cell biology is how membrane proteins are sorted in the endocytic
pathway. The sorting of internalized β2-adrenergic receptors between recycling endosomes …
pathway. The sorting of internalized β2-adrenergic receptors between recycling endosomes …
Amplified RNA synthesized from limited quantities of heterogeneous cDNA.
RN Van Gelder, ME von Zastrow… - Proceedings of the …, 1990 - National Acad Sciences
The heterogeneity of neural gene expression and the spatially limited expression of many
low-abundance messenger RNAs in the brain has made cloning and analysis of such …
low-abundance messenger RNAs in the brain has made cloning and analysis of such …
Cargo regulates clathrin-coated pit dynamics
MA Puthenveedu, M von Zastrow - Cell, 2006 - cell.com
Clathrin-coated pits (CCPs) are generally considered a uniform population of endocytic
machines containing mixed constitutive and regulated membrane cargo. Contrary to this …
machines containing mixed constitutive and regulated membrane cargo. Contrary to this …