The microbial ecosystem of the gastrointestinal tract is characterized by a great number of
microbial species living in balance by adopting mutualistic strategies. The eubiosis/dysbiosis …

Background: Some beneficial effects of probiotics may be due to secreted probiotic-derived
factors, identified as “postbiotic” mediators. The aim of this study was to evaluate whether …

Intestinal bacteria are usually regarded as harmless commensals in healthy intestine but are
pathogens, if these invade the tissues. The mucus gel separates the luminal bacteria from …

The prescribing and use of opioid analgesics is increasing in Italy owing to a profusion in the
number and types of opioid analgesic products available, and the increasing prevalence of …

METHODS: In this randomized, controlled, double-blind, double-dummy, multicenter trial
assessing the efficacy and safety of mucosal protective agent Poliprotect (neoBianacid, …

Background Clostridioides difficile infection (CDI) might be complicated by the development
of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the …

Background Biopsychosocial models for both organic and functional gastrointestinal (GI)
disorders can be found in the literature. To clarify the role of psychopathological factors and …

Strenuous exercise can be associated with “Exercise Induced Gastrointestinal Syndrome” (Ex-GIS),
a clinical condition characterized by a series of gastrointestinal (GI) disturbances that …

1. Davidson A, Diamond B. Autoimmune disease. N Engl J Med. 2001; 345: 340–350. 2. Ginn
LR, Lin JP, Plotz PH, et al. Familial autoimmunity in pedigrees of idiopathic inflammatory …

The novel Regulation 2017/745/EC on medical devices introduces and strengthens the role
of “medical devices made of substances”, which mostly include substances of natural origin. …