Intensive glycemic control (IGC) targeting HbA 1c fails to show an unequivocal reduction of
macrovascular complications in type 2 diabetes (T2D); however, the underlying mechanisms …

Background— Cellular studies showed that histone methyltransferase Set7 mediates high
glucose–induced inflammation via epigenetic regulation of the transcription factor NF-kB. …

Aim Diabetes is a major driver of cardiovascular disease, but the underlying mechanisms
remain elusive. Prolyl-isomerase Pin1 recognizes specific peptide bonds and modulates …

Aims Left ventricular (LV) mass increase is considered part of composite target organ damage
in hypertension and an independent risk factor for cardiovascular (CV) events. This study …

Mandatory working from home is one of the consequences of the COVID-19 pandemic for a
large number of workers. Transition to working from home may significantly impact lifestyle, …

Recent studies suggest strong interactions between cerebrovascular and Alzheimer’s disease
(AD) pathology. These conditions share common risk factors and individuals having both …

A polypill strategy has been demonstrated to improve treatment adherence in several
cardiovascular disease (CVD) settings. However, data on the prognostic impact in the secondary …

Rationale: C2238 atrial natriuretic peptide (ANP) minor allele (substitution of thymidine with
cytosine in position 2238) associates with increased risk of cardiovascular events. Objective: …

Aims Occurrence of heart failure during dialysis treatment is associated with high mortality.
However, mechanisms underlying left ventricular dysfunction (LVD) in these patients are still …

Growing evidence shows that COVID-19 is associated with an increase in Tako-Tsubo
syndrome (TTS) incidence. We collected data from patients hospitalized in our multidisciplinary …