Isolated thrombosis after COVID-19 vaccination: Case series

M Al-Ahmad, M Al Rasheed, L Altourah… - International Journal of …, 2022 - Springer
M Al-Ahmad, M Al Rasheed, L Altourah, T Rodriguez-Bouza, N Shalaby
International Journal of Hematology, 2022Springer
Background Data regarding thrombosis after COVID-19 vaccination are scarce. Methods
Clinical and laboratory data were collected from all patients who developed thrombosis
within 4 weeks of receiving the Pfizer or Oxford/AstraZeneca vaccine. None had a COVID-19-
positive swab. Results Seventeen patients were included, with average age of 48.8 years
and equal proportion of females to males. Our data suggest that thrombosis occurred in 1 in
163,000 of all individuals who had received any dose of any type of COVID-19 vaccine: six …
Background
Data regarding thrombosis after COVID-19 vaccination are scarce.
Methods
Clinical and laboratory data were collected from all patients who developed thrombosis within 4 weeks of receiving the Pfizer or Oxford/AstraZeneca vaccine. None had a COVID-19-positive swab.
Results
Seventeen patients were included, with average age of 48.8 years and equal proportion of females to males. Our data suggest that thrombosis occurred in 1 in 163,000 of all individuals who had received any dose of any type of COVID-19 vaccine: six (1 in 123,000) patients after the first dose of Oxford/AstraZeneca, none after the second dose of Oxford/AstraZeneca, four (1 in 257,000) patients after the first dose of the Pfizer vaccine, and seven (1 in 102,000) patients after the second dose of Pfizer vaccine. Three of 17 patients with thrombosis (17.6%) died.
Conclusions
We believe this report to be one of the earliest in the literature to address the question of whether isolated thrombosis is a possible complication of COVID-19 vaccination.
Springer