Relapse of thrombotic thrombocytopenic purpura after COVID-19 vaccine
C Sissa, A Al-Khaffaf, F Frattini, R Gaiardoni… - … and Apheresis Science, 2021 - trasci.com
We report a case of a 48-year-old white female patient with a history of relapsing thrombotic
thrombocytopenic purpura (TTP). The patient has been known to our department since 2015
when she was diagnosed for the first time with TTP with a high antibody titer (99 U/mL)
against ADAMTS13 (A Disintegrin And MeTalloproteinase with a Thrombo-Spondin type 1
motif, member 13) and very low ADAMTS13 activity (Fluorescent Resonance Energy
Transfer [FRET] assay:< 3%, normal range 45–138%). She was treated with ten plasma …
thrombocytopenic purpura (TTP). The patient has been known to our department since 2015
when she was diagnosed for the first time with TTP with a high antibody titer (99 U/mL)
against ADAMTS13 (A Disintegrin And MeTalloproteinase with a Thrombo-Spondin type 1
motif, member 13) and very low ADAMTS13 activity (Fluorescent Resonance Energy
Transfer [FRET] assay:< 3%, normal range 45–138%). She was treated with ten plasma …