Association of premature natural and surgical menopause with incident cardiovascular disease

MC Honigberg, SM Zekavat, K Aragam, P Finneran… - Jama, 2019 - jamanetwork.com
Importance Recent guidelines endorse using history of menopause before age 40 years to
refine atherosclerotic cardiovascular disease risk assessments among middle-aged women.
Robust data on cardiovascular disease risk in this population are lacking. Objective To
examine the development of cardiovascular diseases and cardiovascular risk factors in
women with natural and surgical menopause before age 40 years. Design, Setting, and
Participants Cohort study (UK Biobank), with adult residents of the United Kingdom recruited …