Analysis of female enrollment and participant sex by burden of disease in US clinical trials between 2000 and 2020
JR Steinberg, BE Turner, BT Weeks… - JAMA Network …, 2021 - jamanetwork.com
Importance Although female representation has increased in clinical trials, little is known
about how clinical trial representation compares with burden of disease or is associated with
clinical trial features, including disease category. Objective To describe the rate of sex
reporting (ie, the presence of clinical trial data according to sex), compare the female burden
of disease with the female proportion of clinical trial enrollees, and investigate the
associations of disease category and clinical trial features with the female proportion of …
about how clinical trial representation compares with burden of disease or is associated with
clinical trial features, including disease category. Objective To describe the rate of sex
reporting (ie, the presence of clinical trial data according to sex), compare the female burden
of disease with the female proportion of clinical trial enrollees, and investigate the
associations of disease category and clinical trial features with the female proportion of …