[HTML][HTML] Venous sinus thrombosis after the second jab of an mRNA-based SARS-CoV-2 vaccine
J Finsterer, S Nics - Brain Hemorrhages, 2022 - Elsevier
J Finsterer, S Nics
Brain Hemorrhages, 2022•ElsevierObjectives Venous sinus thrombosis (VST) after vaccination with the mRNA-based vaccine
produced by Pfizer is comparatively rare and usually occurs after the first dose. VST after the
second dose has been reported in only few patients. Case report The patient is a 33yo male
who experienced an episode of sudden onset focal, stabbing headache in the left temporal
region for about 4 h. Three days later a similar episode occurred accompanied by a focal
seizure. Twenty days before he had received the second dose of the Pfizer vaccine. Clinical …
produced by Pfizer is comparatively rare and usually occurs after the first dose. VST after the
second dose has been reported in only few patients. Case report The patient is a 33yo male
who experienced an episode of sudden onset focal, stabbing headache in the left temporal
region for about 4 h. Three days later a similar episode occurred accompanied by a focal
seizure. Twenty days before he had received the second dose of the Pfizer vaccine. Clinical …
Objectives
Venous sinus thrombosis (VST) after vaccination with the mRNA-based vaccine produced by Pfizer is comparatively rare and usually occurs after the first dose. VST after the second dose has been reported in only few patients.
Case report
The patient is a 33yo male who experienced an episode of sudden onset focal, stabbing headache in the left temporal region for about 4 h. Three days later a similar episode occurred accompanied by a focal seizure. Twenty days before he had received the second dose of the Pfizer vaccine. Clinical exam was normal but MRI of the brain revealed a VST of the left transverse and sigmoid sinuses. Anticoagulation with low molecular weight heparin followed by dabigatran resulted in complete recovery.
Conclusions
This case shows that also the second dose of the Pfizer vaccine can be followed by a VST. Currently, there are more arguments in favour of a causal relation between the vaccination and the VST than against it.
Elsevier