Sex differences in cardiovascular disease–impact on care and outcomes
KH Humphries, M Izadnegahdar, T Sedlak… - Frontiers in …, 2017 - Elsevier
Globally, cardiovascular disease (CVD) is the number one killer of women; one third of
female deaths are due to ischemic heart disease and stroke (WHO, 2013). Historically
considered a 'man's disease', the basic research and clinical trial evidence that underpins
our treatment of CVD is largely based on males. The seminal publication from the Institute of
Medicine–Exploring the Biological Contributions to Human Health: Does Sex Matter
(Wizemann and Pardue, 2001)–laid the foundation for the importance of examining sex and …
female deaths are due to ischemic heart disease and stroke (WHO, 2013). Historically
considered a 'man's disease', the basic research and clinical trial evidence that underpins
our treatment of CVD is largely based on males. The seminal publication from the Institute of
Medicine–Exploring the Biological Contributions to Human Health: Does Sex Matter
(Wizemann and Pardue, 2001)–laid the foundation for the importance of examining sex and …