Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis

P Purkayastha, C Mckechnie, P Kalkur… - BMJ Case Reports …, 2021 - casereports.bmj.com
P Purkayastha, C Mckechnie, P Kalkur, M Scully
BMJ Case Reports CP, 2021casereports.bmj.com
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a relatively novel term
which describes patients who have developed a low platelet count and prothrombotic
tendencies secondary to receiving a vaccine. The concept has been derived from the well-
established phenomenon of heparin-induced thrombocytopenia, and several cases of VITT
have now been reported in patients who have received the AstraZeneca (ChAdOx1 nCov-
19) vaccine. Unfortunately, some of these patients have gone on to develop intracranial …
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a relatively novel term which describes patients who have developed a low platelet count and prothrombotic tendencies secondary to receiving a vaccine. The concept has been derived from the well-established phenomenon of heparin-induced thrombocytopenia, and several cases of VITT have now been reported in patients who have received the AstraZeneca (ChAdOx1 nCov-19) vaccine. Unfortunately, some of these patients have gone on to develop intracranial venous sinus thrombosis. We present a case of VITT-associated sinus thrombosis secondary to the AstraZeneca (ChAdOx1 nCov-19) vaccine, which was complicated by a large intracerebral haemorrhage.
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