Association of aspirin use for primary prevention with cardiovascular events and bleeding events: a systematic review and meta-analysis
SL Zheng, AJ Roddick - Jama, 2019 - jamanetwork.com
Importance The role for aspirin in cardiovascular primary prevention remains controversial,
with potential benefits limited by an increased bleeding risk. Objective To assess the
association of aspirin use for primary prevention with cardiovascular events and bleeding.
Data Sources PubMed and Embase were searched on Cochrane Library Central Register of
Controlled Trials from the earliest available date through November 1, 2018. Study Selection
Randomized clinical trials enrolling at least 1000 participants with no known cardiovascular …
with potential benefits limited by an increased bleeding risk. Objective To assess the
association of aspirin use for primary prevention with cardiovascular events and bleeding.
Data Sources PubMed and Embase were searched on Cochrane Library Central Register of
Controlled Trials from the earliest available date through November 1, 2018. Study Selection
Randomized clinical trials enrolling at least 1000 participants with no known cardiovascular …