Having a background playing Banished, it really helped with the learning curve.
There is lots to do on this little red planet in so little time.

For those considering purchasing this game, this word soup is for you:

The first epidemic you'll face is the age of lazy welfare sucking seniors. Non-contributing members of the harsh Martian colonisation effort. In this game, seniors do not work; ergo, they do not contribute to the efforts. They leech your resources, and take up valuable real estate that could otherwise be occupied by fertile, sexy, rizzed up Martians. Let me save you hours of time and a few re-do's: I realised that suffocating the seniors in their own dome was so much easier, more efficient, economically friendly, and ultimately (after like 5 failed attempts) sent me into a rapture of satisfaction; feeding them and supplying them with housing, water, food, and oxygen became an option - Finally! this game started to really open up for me! *wipes evil tear*
I mean....You could go the [arguably] slightly less extreme route and actually feed them, and keep them alive (yawn). But ultimately, you'll want to isolate the seniors in their own domes and keep them away from your valuable housing vacancies in your working domes so your vigorous, youthful Martians can get to slappin' cheeks! ;)

The second epidemic you'll face will be resource management. You will probably learn how to deal with this issue long before your seniors start terrorising your casino's on bingo nights. But keep in mind that resources like water never stop extracting, so managing how much you pull out of the ground versus what you can store and save versus what you cyclically use should contrast with when to turn your factories and machines on and off to save valuable power and resources. This becomes especially important as you scale the difficulties and select landing sites on Mars that are more resource scarce than other locations. (Helpful tip for beginners: If you want the most resource rich location on Mars to start your first colony, use coordinates 4S112E at the selection screen)

I recommend you max out research in your Physics, Engineering, Biotech, Social, and Robotics trees BEFORE you invest any Science into the Terraforming, or Recon & Expansion trees. UNLESS your plan is to mine asteroids, or delve into the underground early, then maybe dump some brainpower into Recon & Expansion. Terraforming is late game grunt work, I wouldn't worry about this until your colony has stabilised a little bit and you've got a comfortable groove set in.
On the topic of Science. OUTSOURCE!!!! this is the best use of your capital. The better tech you get the easier the game becomes. Use your money to outsource whenever you have the funds. The early techs are as inexpensive as 1000 Science each, but the late game techs are tens of thousands of Science per selection; be wise with how you spend this currency, it costs time, not just science. Establishing a solid foundation for research is fundamental to developing a successful colony. Research labs, and Hawking Institutes will form the bulk of your Science department for most of the game, however if you're struggling early on getting science, it might be worth it to dip your toes into the Recon & Expansion tree to get the Recon Centres - They can seek out discoveries in the cosmos (as well as discover resource rich asteroids) to give you a couple thousand extra science from time to time.

Be very picky of your first 12 founding colonists. Don't accept mediocre. You want the Sexy, and Workaholic traits if you can get them, and get an even number of males to females (obviously). Your Earthling Martians need to be Hard working and DTF!!!! The idea is to get off the proverbial nipple, and build a regenerative colony. And NOTHING regenerates like sexy, hardworking Space Cowboys! Yeehaw!

Use the time selection to your advantage. Being able to pause and speed up the game is extremely useful when trying to manage the clock. Your spacebar is your friend!

Build domes that work for your colony and you. I know it sounds like a great idea, but don't build the "Las Vegas Dome" where all your colonists can just go kick it and have a fun weekend. Outfitting it with a few casino's, a wonderful place where your colonists can go watch the rocket launches, and get f'd up at the Space Bar during the all day cocktail hours - This is a waste of valuable resources and real estate (go ahead, ask me how I know this). Your colonists are not community college frat boys looking for a good time. They're FORMER community college frat boys looking for a good time, who just so happen to be on a sponsored suicide mission to the Big Dead Red - We need them SHARP and PRODUCTIVE! Bare in mind when assembling the guts of your domes; your essential kit is Housing, Infirmary, Grocery, Diner, and a fountain/pond, you might need an Electronics Store to satisfy some gaming needs that might be a requirement of some colonists, but for the most part this is the bare minimum to maintain sanity to a level that encourages reproduction. I recommend building a separate dome exclusively for the freshly born Martian crotch-goblins and have this outfitted with nursery's, schools, and playgrounds. This will keep the children out of your "fertile" domes [aka they wont be taking up housing vacancies in domes where you need as many occupants "busting the bed springs" as possible.]

The martian rail lines are very useful for accessing remote areas from you main populous. I use this for getting resources trapped in deplorable areas of the map. I have had issues with salvaging/deleting rail lines and stations in a few games, and in others, they delete just fine. So they're moody - great...

All in all, I like this better than Banished. I wish there was more content in the workshop, but honestly, I don't think the game needs it.

Good luck and Godspeed everyone!

The game is gun and quite addictive. Despite the steer learning curve, it is actually very easy.

I like the game