This is my runthrough of Deathloop. I decided to try and break the loop as efficiently as possible and I broke it on Loop 7! The first one is fully scripted, and Loop 2 and 3 have pretedermined destinations, so you are only fully free to explore from Loop 4 onward.

Just a disclaimer, this is NOT a speedrun - I take my time, sneak around, have fun and have some more fun and have some fun in the process... Below is a full breakdown of my approach. Enjoy!

Loop 1 starts at 0:00 in the video and is fully scripted, so have fun!

LOOP 2 starts at 8:00 in the video and is partially scripted.

1. Updaam - Morning

• Reveal the RAK door
  
• Visit Colt's flat
  
• Prevent the fire to Otto’s

2. The Complex - Noon

• Visit the Loop Control Center and watch the explanation

3. Fristad Rock - Afternoon

• Get info on the LPP from the AEON Program's Security Office
  
• Reveal the code for Charlie's safe in Karl's Bay at the bunker

4. Updaam - Evening

• Check Colt's safe at his flat
  
• Visit Otto’s to find the code to access the fireworks
  
• Get Aleksis' safe code from his room

Loop 3 starts at 34:00 in the video and is partially scripted.

1. Updaam - Morning

• Visit Colt's flat and check the safe

2. The Complex - Afternoon

• Kill all Wenjies and complete the experiment

Loop 4 starts at 52:00 in the video and this is the point from which you can collect the rest of the clues in any order.

1. Karl’s Bay - Morning

• Open Charlie's safe and find clues on the cipher

2. Fristad Rock - Noon

• Reveal the symbols for Fia's cipher

3. Updaam - Afternoon

• Visit the archivist’s office
  
• Retrieve the code for the power stations’ controls from RAK

4. The Complex - Evening

• Get the password to Egor’s hidden device from his notes
  
• (Optional) Pick up the silenced LIMP-10

Loop 5 starts at 1:15:30 in the video.

1. The Complex - Morning

• Power up Updaam and Karl’s Bay’s power stations

2. Updaam - Noon

• Visit the Yasen Station
  
• Kill Charlie and take his Slab (this may be optional but Shift is very useful later on, so I never tried to skip it)

3. The Complex - Afternoon

• Get clues for Wenjie's wish from her room

4. Karl’s Bay - Evening

• Visit the Akkar Station

Loop 6 starts at 1:42:30 in the video.

1. The Complex - Morning

• Power up The Complex and Fristad Rock’s power stations
  
• Visit the HZN Station

2. Updaam - Noon

• Take the Aleksis statuette from the safe to 2-BIT
  
• Instruct 2-BIT to play the recording to “Give Wenjie what she wants”

3. Fristad Rock - Afternoon

• Visit the Sova Station

Loop 7 - the final loop starts at 2:01:40 in the video.

1. Karl’s Bay - Morning

• Sabotage Frank’s fireworks (rain flaps)
  
• Kill Harriet

2. The Complex - Noon

• Ruin Egor’s experiment

3. Fristad Rock - Afternoon

• Enter the bunker and flood it to kill Charlie and Fia

4. Updaam - Evening

• Crash the party and kill Wenjie, Egor and Aleksis
  
• Go to RAK and launch away from Updaam

5. Somewhere - Sometime

• Pick the ending of your choice!

That's it! Have you found a faster way to break the loop? Please share below if you have so I can try it out.