IMPC - International Mouse Phenotyping Consortium

🚨 Data release and new website alert! Data release 22 is live on the IMPC web portal with a new website and improved user journey. Phenotyping data is available for 9,073 genes with around 2.9 million new data points visualised with updated graphs and tables!    With our new website we are introducing new features that will allow the users to enjoy; 📚 Supporting datasets for each phenotype association now summarised on the chart pages.  📊 On the phenotype pages a new interactive graph provides an overview of the phenotype associations across the analysed genes.  🧬 Easier comparison of phenotypes for alleles of the same gene on the gene pages.    More on the new website features and data release here:  https://lnkd.in/ef2kGnzw #IMPC #mouse #genetics #phenotyping #data 

The 2024 series IMPC Virtual Workshop "Sharing Approaches to Model Cardiovascular and Metabolic Disease." is just 3 days away! Remember, registration is free but obligatory. 🗓 Date: November 7, 2024 📍 Location: Online (Virtual) To register and more: https://lnkd.in/eAx9fJdq

Join us Nov 1 for Gene Sequencing for Functional Knowledge! 🧬 MBP experts reveal breakthroughs in genetics. Register now: https://lnkd.in/guVg_Qej

🌟 Join Us for the first in the 2024 series IMPC Virtual Workshop! 🌟 "Sharing Approaches to Model Cardiovascular and Metabolic Disease." 🗓 Date: November 7, 2024 📍 Location: Online (Virtual) Dive into the approaches to model CVD and Metabolic disease and listen to leading experts in the field at the 1st IMPC workshop in the 2024-2025 series. The event promises to expand knowledge, connect with peers and offer a platform for dynamic exchange of ideas for both researchers and clinicians. Registration is free but obligatory https://lnkd.in/dUxJHVbH

Curious about the science behind our mice? 🐭 Unlock the secrets in a new Mammalian Genome publication about us: https://lnkd.in/gJCiQEJb!

🚨 Come and join our virtual workshop! 🚨 Our next virtual workshop on ‘Sharing Approaches to Model Cardiovascular and Metabolic Disease’ will be held on the 7th of November. Check out our news post for more details and join us for the exciting talks: https://lnkd.in/eAx9fJdq.

In two studies recently published in Cell and Science, scientists at MRC Laboratory of Molecular Biology (LMB) and the UK Dementia Research Institute at University of Cambridge explored a new therapy for Alzheimer’s disease and potentially other neurodegenerative conditions. The protein - called TRIM21 - selectively destroyed aggregated tau proteins, leaving healthy tau proteins intact. Whereas current antibody therapies have a hard time accessing tau tangles that live inside of brain cells, TRIM21 is able to enter the cell and effectively destroy the tau aggregates. When given to elderly mice with tau proteins, the result was a significant reduction in tau and decreased symptoms of neurodegeneration, including improved walking ability. Despite this exciting finding, the scientists explain that these therapies still require a lot of development before they can be tested in humans. Read more: https://lnkd.in/edkW3Dbt #AnimalResearch #AlzheimersDisease #Neurodegeneration #NewScience #NewResearch #MedicalResearch #ResearchTransparency

🎉 Kicking off the #INFRAPLUS project! We’ve just wrapped up two dynamic days in Munich, celebrating the launch of our new project at INFRAFRONTIER. Great discussions, plenty of ideas, and the drive to take them to the next level. Over the next three years, we’re focused on expanding our capabilities to offer cutting-edge in vivo and in vitro models, along with innovative preclinical and data analysis services. With a clear mission to reduce animal use in biomedical research and lower our environmental impact, we are ready to meet global biomedical challenges head-on. Exciting times ahead! #Innovation #BiomedicalResearch #Sustainability #INFRAPLUS #INFRAFRONTIER #GlobalChallenges 🇪🇺 INFRAPLUS has received funding from the European Union’s Horizon Europe research and innovation programme under grant agreement No 101131669.

🌟 New IMPC Chair elected 🌟 We're excited to announce that Dr. Sabine Hölter-Koch has been elected as the first female Vice Chair for IMPC. She will join Jason Heaney, Chair, and Yann Herault, past Chair in the IMPC Senior leadership team from 1st January. Read more: https://lnkd.in/dmuD7iUw Sabine Hölter-Koch

The 2024 internal IMPC-KOMP2 Fall meeting continuous for the second and final day today. In these two days we've had productive Working Group meetings, with interesting presentations, fruitful discussions and lots of enthusiasm to continue to progress within IMPC! #IMPC2024 #mouse #genetics #scientificdiscussion #data