Video Journal of Neurology (VJNeurology)

#NEW from #MDS2023 | The multifaceted nature of #Parkinson’s disease: potential treatment targets 🎥 🧠 Gennaro Pagano, MD, MSc, PhD, Roche Pharma Research & Early Development, discusses the multifaceted nature of #Parkinsonsdisease and the various factors contributing to its development and progression While #alphasynuclein is recognized as a key driver of the disease, #inflammation and dysfunctional #lysosomes also play a role. Targeting all these factors simultaneously could potentially help prevent the disease💡 Additionally, direct targeting of #microglia, which are activated by aggregated #proteins and #neuronal loss, is being explored as a strategy Find out more 👉 https://lnkd.in/etXJQ6fH #Neurology

Physical activity plays a key role in both #stroke prevention & #rehabilitation🚶🧠 Watch our interview with Avril Mansfield, PhD, Toronto Rehabilitation Institute (KITE), University Health Network, who highlights its importance as a rehabilitation method for patients who have had a #Stroke💡 Patients recovering from #stroke are often deconditioned; this may be due to pre-#stroke inactivity or the consequences of the #stroke Aerobic #exercise has been shown to improve #physicalfitness, #endurance, walking speed, and #cognition. This allows for the patients to gain their independence and carry out everyday activity more successfully 💪🏋️ Learn more 👉 https://lnkd.in/ekSHPJ9U #WorldStrokeDay #Neurologynews #VJNeurology

Each year, 12 million people experience a #Stroke 🌍 🧠 But up to 90% of strokes are preventable!💡 This means #StrokeAwareness and prevention is crucial. It is important to take small steps each day to be #GreaterThan stroke!💪 Check out our stroke channel for the latest news and updates 👉 https://lnkd.in/dmaRP4tZ #WorldStrokeDay #Neurologynews #VJNeurology

Join us for our upcoming webinar: 'Translating Novel Diagnostics into Practice: Updates for #NeurodegenerativeDiseases' 🧠 📣 🗓️ 4 November 2024 ⏰ 9:00-11:00 CST / 15:00-17:00 GMT / 16:00-18:00 CET 💬 Chaired by Prof. Charlotte Teunissen Co-moderated by Dr Nicholas Ashton & Prof. Malú Gámez Tansey REGISTER 👉 https://lnkd.in/g_cVKJ5R Agenda 📝 👉 hhttps://lnkd.in/g_cVKJ5R #Neurology #VJNeurology #Neurologywebinar #Neurologynews

October 29th is #WorldStrokeDay 🧠 🌍 Today, join us in raising awareness of the importance of #Stroke prevention! Let's all take steps to be #GreaterThan stroke 💪 In an interview from #ESOC2024, Mira Katan, MD, MSc, FESO, University Hospital and University of Basel gives insight into the use of #biomarkers to individualize secondary prevention in #ischemicstroke Dr Katan explains that #stroke is a #heterogeneousdisease with various causes, including #embolic events, #atherosclerosis, #vasculitides, and #arterialdissection. Identifying the exact cause is challenging, with up to 25-30% of cases remaining unexplained despite thorough investigation💡 #Biomarkers could play a crucial role in pinpointing these underlying causes, leading to more #personalized secondary prevention strategies. Dr. Katan also discusses the ongoing #Mosestrial, which uses a #biomarker (#MRproANP) to guide preventive treatment decisions, aiming to improve outcomes by targeting the specific physiological mechanisms behind #stroke 🌟 Learn more 👉 https://ow.ly/Q5vm50TSpAL #WorldStrokeDay #StrokeAwareness #GreaterThan #VJNeurology #Neurologynews

MMP is seeking a Junior Designer to work alongside our Lead Designer to support the team in producing visually compelling designs that align with the style of our video journals and events - take a look 🗞️ 🎨👇

Interested in hearing from Prof. Ashkan Shoamanesh on '#Andexanet for factor Xa inhibitor–associated acute #intracerebral #hemorrhage'? 🤔 🧠 Join us for our upcoming webinar: 'Evolving Strategies in #Stroke Management'! 📣 👉 https://ow.ly/9biV50T24BN 🗓️ 6 November 2024 ⏰ 10:00-12:00 CST / 16:00-18:00 GMT / 17:00-19:00 CET 💬 Chaired by Prof. Simona Sacco, President-Elect of the European Stroke Organisation Co-moderated by Prof. Ashkan Shoamanesh & Prof. Rustam Al-Shahi Salman. REGISTER 👉 https://ow.ly/9biV50T24BN We will also explore: 💡Session 1: Novel approaches using #thrombolytics in #ischemicstroke with Shelagh Coutts, Vignan Yogendrakumar, Yunyun Xiong & Mouhammad Jumaa 💡Session 2: Latest in #clinical decision-making in #ischemicstroke with Zixiao Li, Craig Anderson, Valeria Caso & Daniel Strbian 💡Session 3: Recent progress in #hemorrhagicstroke management with Gustavo Pradilla, Ashkan Shoamanesh & Urs Fischer & Jürgen Bec #Neurology #VJNeurology #Neurologywebinar #Neurologynews

Want to hear about the current state of clinical evidence regarding the use of #stemcell therapies in patients with #MultipleSclerosis? 🤔 🎥 🧠 Watch our interview with Andrew Wolf, MD, University of Colorado School of Medicine 👉 https://ow.ly/u8YY50TIxC1 He outlines the state of #clinicalevidence regarding the use of #stemcells in #multiplesclerosis (#MS) #Hematopoietic #stemcelltransplant has been evaluated in a number of smaller trials and retrospective studies and is being compared to highly efficacious disease-modifying agents, such as #ocrelizumab, in the large ongoing BEAT-MS (NCT04047628) trial💡 There is also a growing body of exploratory data from Phase I trials exploring other #stemcelltherapies. These involve #intravenous, #intrathecal, or #intraventricular administration of #stemcell products in the hope that they will have an #immunomodulatory effect and reduce #inflammation or that they will aid in #neuroprotection and regeneration #MS #MultScler #AANAM #NeuroTwitter #Neuroscience

NEW on VJToday: '#FDA approves #foslevodopa-#foscarbidopa: a breakthrough continuous #infusiontherapy for advanced #Parkinsonsdisease' 🗞️ 🧠 On October 17, 2024, AbbVie announced the U.S. Food and Drug Administration (FDA) approval of foslevodopa-foscarbidopa, marking the first and only subcutaneous 24-hour continuous infusion of #levodopa-based therapy for #motor fluctuations in advanced #Parkinson’s disease (PD) #Foslevodopa-#foscarbidopa is set to provide a #nonsurgical option for patients facing the limitations of oral medications and offer continuous #levodopa delivery throughout the day and night 💊 In this article we cover: 💡 Motor fluctuations in PD 💡 About foslevodopa-foscarbidopa 💡 Pivotal Phase III M15-736 and M15-741 studies 💡 Safety profile 💡 Looking ahead & we hear from Angelo Antonini MD, PhD, Università degli Studi di Padova: "...the main advantage of this formulation is that you can bring into the syringe up to four grams of #levodopa, so essentially covering the entire spectrum of doses possible in #Parkinsonsdisease. Also, it allows…delivery for 24-hours, at the same infusion rate or with different infusion rates according to the patient need, so it can be customized" 💬 🔦 Explore the article and learn more about the study 👉 https://lnkd.in/dFwRqGrg #VJNeurology #Neurologynews

Interested in hearing from Suzanne Schindler about 'Acceptable performance of #bloodbiomarker tests of #amyloid #pathology – recommendations from the global CEO initiative on #Alzheimersdisease'? 🤔🩸 🧠 Join us for our upcoming webinar: 'Translating Novel Diagnostics into Practice: Updates for #NeurodegenerativeDiseases'! 📣 🗓️ 4 November 2024 ⏰ 9:00-11:00 CST / 15:00-17:00 GMT / 16:00-18:00 CET 💬 Chaired by Prof. Charlotte Teunissen Co-moderated by Dr Nicholas Ashton & Prof. Malú Gámez Tansey REGISTER 👉 https://ow.ly/G7Ea50TFHNm We will also explore: 💡Session 1: Updates in #Parkinson’s disease with Michael Bartl 💡Session 2: Role of #taubiomarkers in #Alzheimer’s disease diagnosis and staging 💡Session 3: Utility of #blood and #fluidbiomarkers for #Alzheimer’s disease with Giovanni Bellomo, Sebastian Palmqvist & Charlotte Teunissen 💡Session 4: Guidelines and recommendations for #dementiadiagnosis and staging with Clifford R. Jack Jr, Federico Massa & Suzanne Schindler 💡Session 5: Additional advances in #dementiadetection with Dirk Smeets & Katharina Bolsewig #Neurology #VJNeurology #Neurologywebinar #Neurologynews