Using package managers for full-stack web development doesn't have to be difficult, but it does involve some basic steps and best practices. Initializing your project is the first step, which requires creating a package.json file (for npm or yarn), a requirements.txt file (for pip), a Gemfile (for bundler), or a composer.json file (for composer). This file contains the project's metadata and configuration, such as the name, version, description, license, scripts, and dependencies. After that, you use the package manager's command (such as npm install, yarn install, pip install, bundler install, or composer install) to download and install the necessary dependencies. A lock file is then created to record the exact versions and sources of those dependencies. You can also use the package manager's command (such as npm update, yarn upgrade, pip update, bundler update, or composer update) to update or uninstall the dependencies that you no longer need or want to upgrade. Additionally, you can use the package manager's command (such as npm audit, yarn audit, pip check, bundler audit, or composer diagnose) to check for any security or compatibility issues with your dependencies. Finally, you can use the package manager's command (such as npm publish, yarn publish, pip upload, bundler push, or composer publish) to publish and share your own packages with other developers. Similarly you can use the package manager's command (such as npm install <package>, yarn add <package>, pip install <package>, bundler add <package>, or composer require <package>) to install and use packages from other developers.