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🗞️Chimeric Therapeutics (ASX: CHM) partners with US #biotech firm to expand cell therapy reach | Media coverage by Kalkine Media Australia https://lnkd.in/gRnsXNBU
Achieve Clinics was formed to empower cancer patients with a new paradigm for accessing and accelerating cell therapy breakthroughs. With our unique ability to partner with industry and leading clinical sites to conduct proactive apheresis (PRO-Aph™ or pro-aph™), we are building a powerful, first-in-class collection of on-demand, disease-relevant (and potentially chemotherapy-naïve) immune material - the critical fuel for powering the next wave of curative cell therapies. The Achieve PRO-Aph platform is unlocking a new standard for high-speed, high-performance innovation across the cancer cell therapy landscape.
External link for Achieve Clinics
Los Angeles, CA, US
Achieve Clinics reposted this
🗞️Chimeric Therapeutics (ASX: CHM) partners with US #biotech firm to expand cell therapy reach | Media coverage by Kalkine Media Australia https://lnkd.in/gRnsXNBU
Achieve Clinics reposted this
🗞️Chimeric Therapeutics (ASX: CHM) partners with US #biotech firm to expand cell therapy reach | Media coverage by Kalkine Media Australia https://lnkd.in/gRnsXNBU
Achieve is proud to take part in supporting the development of Chimeric's novel cadherin 17-directed CAR-T for solid tumors with our powerful platform for proactive apheresis. That we can share this news on World Cancer Research Day feels especially fitting. We look forward to this opportunity to demonstrate how Achieve's free-to-patient PRO-Aph platform can transform patient access and accelerate development timelines, especially in settings where "brain-to-vein" delays can lead to slowed study enrollment and patients ultimately untreated with potentially curative cell therapies. Congratulations to the Chimeric Therapeutics and Achieve Clinics teams on establishing this groundbreaking collaboration!
We've partnered with Achieve Clinics to expand the reach of our CHM CDH17 cell therapy, the world’s first cadherin 17-directed CAR-T therapy. The partnership will enable the use of product collected from apheresis, which is cryopreserved from patients according to Achieve Clinics process, for the manufacture of CHM CDH17. “The use of patients’ cells that have previously been exposed to chemotherapy and the logistical challenges of just-in-time manufacturing have a negative impact both on patients trying to access these new medicines and cell therapy companies working to advance their clinical programs,” said Jason B Litten MD, Chief Medical Officer of Chimeric. “We believe Achieve’s revolutionary approach will streamline our future development plans and make it easier for patients to access CHM CDH17.” “Achieve is excited to support Chimeric’s clinical trial, especially given that it is one of the only CAR Ts with IND clearance in advanced gastrointestinal cancers,” said Brad Heller, PhD, Chief Executive Officer of Achieve Clinics. “Advanced GI cancer patients are prone to bleeding issues that make apheresis risky, so being able to support this patient population early in their cancer treatment is especially meaningful. We are excited to help more patients gain easier access to CHM CDH17, while improving accrual rates and development timelines.” Read the full ASX Announcement here: https://lnkd.in/ghZX8YTB #ChimericTherapeutics #CHM #AchieveClinics #CellTherapy #CHMCDH17 #CancerResearch #GICancer #CARTCellTherapy #PROAph #ClinicalTrials #BiotechInnovation #CancerTreatment #ASXNews #ASX
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Just returned from my first ASCO! With all the people I met and things I learned at the meeting, one of the highlights of my trip to Chicago was actually offsite! I finally met IRL Amittha Wickrema, the director of University of Chicago's Cell Therapy Manufacturing Facility after years of virtual meetings. Along with Michael R. Bishop, M.D., Amittha has been a friend and champion of Achieve Clinics' new approach to cell therapy manufacturing. Thank you both for your ongoing help and support!
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After an incredible ISCT in Vancouver, fortunate to have made a pitstop in Seattle. Beyond visiting various friends, family, and colleagues, had the very special delight to sit down with none other than Brady Lucas, M.Ed. CHES®, the author of Smiley's Smile (Amazon link: https://a.co/d/iloEfqC) and survivor/thriver through 2 separate bouts of childhood cancer. On this day after National Cancer Survivors Day, what a treat to be inspired by the various ways Brady is advocating for patients and working to help make sure patients and families can be educated as effectively as possible about the cancer patient's journey and be empowered to access their best possible outcomes. It was already amazing to see Emily and Tom Whitehead personally inspire the ISCT community last week, but my heart is overflowing: there are indeed so many important stories to pay attention to and tell. So excited and honored to help Achieve Clinics play its part. #NCSD2024 #ISCT #SmileEveryDay
Can a cancer patient's T-cells be engineered into CAR-Ts capable of overcoming the immunosuppressive environment common in solid tumors such as pancreatic ductal adenocarcinoma (PDAC)? We are thrilled to take part in making progress on this question. The 2024 American Society of Clinical Oncology (ASCO) Annual Meeting poster titled, "Antagonizing vasoactive intestinal peptide (VIP) receptors with Muc16CD-directed armored CAR T cells for pancreatic cancer." highlights the potential of a novel CAR design that modulates the emerging VIP checkpoint pathway to metabolically reprogram CAR-Ts towards a memory-rich cell product - even when engineered into actual PDAC patient immune cells. Congratulations to first author Heather Lin from the Sarwish Rafiq, PhD lab and colleagues from Emory University, along with co-authors Brad Heller and Paul Chun from Achieve. Link to Abstract: https://lnkd.in/gy-UNTsp #ASCO24 #celltherapy #oncology #pancreatic
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I was excited and honored to see a picture of me holding Emily on the beach at OCMD in the add for our feature documentary film, titled- OF MEDICINE AND MIRACLES, which is now available to watch on Amazon (Prime TV), Apple +, Youtube, and Vimeo. Many people working on these new advanced therapies have asked when it would be available to watch at home, so they can show their families, this is why I go to work. #ActivateTheCure #emilywhiteheadfoundation #WeBelieve #science #miracles #universityofpennsylvania #childrenshospitalofphiladelphia
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Attention early-stage investigators! Applications are still being accepted for The Emily Whitehead Foundation $50,000 “Fight for Cures” grant to support an early-stage investigator working in the U.S. who is dedicated to advancing novel cell and gene therapies. The grant will be awarded to an early-career scientist who is emboldened with the indomitable and unconquerable spirit of Nicole Gularte to develop, create and deliver access to advanced therapies for pediatric patients and significantly contribute to the field of advanced therapies. Deadline to submit an application is June 15, 2024. Apply today: https://lnkd.in/e3Xkzm5S
We have much news to share in the coming days from what has been a momentous chapter in our story. Stay tuned. In the meantime, one teaser is the delightful chance we had to meet and share Achieve alongside so many inspired founders with the San Diego Angel Conference community. We could not be more honored by and grateful for SDAC's decision to join us as partners in our mission: to serve patients and empower them to access and accelerate powerful innovations in cell therapy. Thanks for all the love, San Diego! ❤️ 🙏 🤝
We are thrilled to announce the winners of San Diego Angel Conference VI: Ecodrive and Achieve Clinics. At the SDAC VI Finale this past Thursday, our team of angel investors chose to invest $300,000 in first place winner Ecodrive, while Achieve Clinics was the runner up and received $100,000. As we celebrate the success of these two incredible companies, we look forward to witnessing their continued impact. Congratulations to Ecodrive’s Blake Ruschman, Trevor Laudate, and Markus Rommel and Achieve Clinics’ Paul Chun and Brad Heller for their dedication, vision, and determination! #SanDiegoAngelConference #InnovationChampions #Ecodrive #AchieveClinics
Is there a better day in May besides May 10th? This date should be enshrined as a National or International holiday in our opinion!
Today Emily is 12 years cancer free and she just finished her first year at University of Pennsylvania. Our goal is to help get these advanced therapies to patients globally! Thank you to everyone making this happen!