Avista Therapeutics

Avista Therapeutics

Biotechnology Research

Pittsburgh, PA 1,653 followers

Developing innovative gene therapies for retinal diseases that have a profound impact on patients' quality of life.

About us

Avista's mission is to develop innovative gene therapies for retinal diseases, including rare, inherited conditions that have a profound impact on patients' quality of life. We leverage our computationally guided scAAVengr platform to generate and validate a toolkit of proprietary AAV vectors that overcome the most significant obstacles to effective gene therapies, including cell-type specific delivery, reduced dosages, and efficient expression, using a minimally invasive intravitreal approach. Our quantitative, in vivo-based approach and clinical ophthalmology expertise allow us to rapidly translate new gene therapies to the clinic. Avista is a UPMC Enterprises portfolio company founded based on the research of Drs. Leah Byrne, Jose Sahel, and Paul Sieving.

Industry
Biotechnology Research
Company size
2-10 employees
Headquarters
Pittsburgh, PA
Type
Privately Held
Founded
2021

Locations

Employees at Avista Therapeutics

Updates

  • View organization page for Avista Therapeutics, graphic

    1,653 followers

    Join us for a lecture on "Prosthetic vision in patients with atrophic AMD"! Dr. Daniel Palanker from Stanford is visiting the department on November 6 as part of our Distinguished Lecture Series. We hope to see you there: November 6th 12:30pm at Pitt in 4.221.

  • View organization page for Avista Therapeutics, graphic

    1,653 followers

    Some Inherited Retinal Diseases (IRDs) are simpler to treat than others. For example, there are over 60 known genes to cause retinitis pigmentosa — This makes gene therapy very challenging. Thankfully we have some of the best scientists in the business working on gene therapies at Avista TX. Find out more about us and our work: avistatx.com

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  • View organization page for Avista Therapeutics, graphic

    1,653 followers

    MEET OUR TEAM: Christopher J. Morrison serves as Senior Vice President of CMC. Chris brings to Avista over 10+ years of direct AAV CMC experience working at a number of startups, including Dimension Therapeutics (now part of Ultragenyx), Voyager Therapeutics, Adverum Biotechnologies, and most recently Myrtelle, Inc. as Head of Technical Operations. Having worked on over 20 different rAAV therapeutic candidates to date, Chris has led the development and implementation of both early and late-stage manufacturing processes, with corresponding analytics, for products of assorted serotype and genomic construct produced by Sf9-Baculovirus, HeLa-Adenovirus or HEK293 transient transfection-based production systems. Prior to AAV startups, he began his industrial career at Pfizer, working on the downstream purification processes for various CHO based therapeutics. He holds a B.S. in Chemical Engineering from the University of Wisconsin – Madison and a Ph.D. in Chemical and Biological Engineering from Rensselaer Polytechnic Institute with a focus on chromatographic bioseparations. Learn more about our team: avistatx.com

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