Bioelectronics Drop

A #wearable metal detector to track spinal implant integrity 🤠 Publishing in Nature Communications, scientists from Massachusetts Institute of Technology, The University of Hong Kong, and Zhejiang University led by Giovanni Traverso devised an adhesive array of metal detectors that provides dynamic and real-time tracking of the position and integrity of spinal implants. The new approach allows postoperative monitoring, crucial for the early detection and diagnosis of hardware failures Article available open access at Nature Portfolio https://lnkd.in/e_eGiFYx

Sweat-powered wearables for continuous health monitoring ☝ Publishing in Nature Electronics, Scientists at UC San Diego led by Shichao Ding, Tamoghna Saha, Lu Yin, and Joe Wang devised a fingertip-wearable system to monitor the chemical composition of sweat. #Sweat also provides the energy supply for electronics and wireless communications via an enzymatic reaction and therefore needs no external battery. Article available at Nature Portfolio https://lnkd.in/er2FbJ4x

Electrical sensing and chemical delivery to treat #epilepsy 👩⚕️ Publishing in Brain, scientists at Massachusetts Institute of Technology and MIT Koch Institute for Integrative Cancer Research led by Michael Cima propose a minimally invasive system that can record deep brain activity and release antiepileptic drugs in situ when seizures occur. While still a proof-of-concept demo in mice, the idea holds great potential for closed-loop devices that intervene during epileptic events, especially in subjects who do not respond to oral drugs. Preview available at https://lnkd.in/emAZqsEt

Adaptive #stimulation improves PD symptoms 👩⚕️ In a randomized clinical trial just published in Nature Medicine, researchers from University of California, San Francisco led by Carina Oehrn, Stephanie Cernera, PhD, and Lauren Hammer, showed that an upgraded version of DBS featuring a patient-tailored algorithm that auto-adjusts the stimulation amplitude improved quality of life and motor symptoms of Parkinsonian participants. Article at Nature Portfolio: https://lnkd.in/gHtuTF49

A bright future for bioelectronic medicine! This market is now predicted to reach >$29B by 2031 due to: 📈 the rising prevalence of neurological illnesses 🛠️ manufacturers investing in R&D ✅ increasing frequency of regulatory approvals https://lnkd.in/eDBscfSb #neurotech #bioelectronicmedicine #business

It's exciting to see the incredible momentum that bimodal neuromodulation treatment for tinnitus is gaining, along with the growing body of scientific evidence supporting its efficacy and positive impact, particularly for patients experiencing significant tinnitus-related distress. #Neuromod Devices #tinnitus #hearinghealth #audiology

Another step forward towards the accurate evaluation of reliability of bioelectronic systems! I am happy to share our latest work published in Nature Communications (Nature Portfolio) where we propose a fully wireless, battery-free, flexible, implantable and modular platform for real-time monitoring of water permeation into thin-film bioelectronics. Wirelessly powered, this innovative device can be integrated into more sophisiticated implants, serving as a module for evaluating their lifetime and stability. Backscatter communication is used for real-time data transmission and leveraged through the integration of thin-film Magnesium (Mg)-based microsensors. The platform represents a pioneering step towards innovative wireless units for in-situ quality control of advanced thin-film bioelectronics. Please find more details here: https://lnkd.in/gx6fi78S. This activity started from a Master thesis project at EPFL , carried on tirelessly and enthusiastically by Francesco Cecchetti, whom I supervised together with Dr James Rosenthal (now at CSEM), expert electrical engineer. We combined expertise of materials science, microfabrication, systems engineering, wireless backscatter communication and theoretical analysis. Huge thanks to Dr Mingxiang Gao (now at IT'IS Foundation) and Prof. Anja Skrivervik (head of the Microwave and Antenna group at EPFL), for their expertise with flexible RF antennas, whose design and implementation are of paramount importance for wireless implantable interfaces. The work was carried out within a joint project between the Laboratory for Soft Bioelectronic Interfaces (LSBI) and the Laboratory for Processing of Advanced Composites (LPAC) of EPFL, and supervised by Profs. Stephanie Lacour and Yves Leterrier. Stay tuned for more!

2D materials for minimally invasive brain surgery 👨⚕️ Researchers at Yonsei University and Gbrain led by Jong-Hyun Ahn proposed a device that can be injected through a tiny hole onto the cortex and expands to cover a large area. It comprises graphene multi-channel electrodes for neural recording and electrical stimulation and MoS2-based sensors for monitoring intracranial temperature and pressure. Article out in Wiley Advanced Materials: https://lnkd.in/gaP3m_7n

Inject → self-assembly → operate → degrade 🔥 A new work in Nature Communications led by Umut Aydemir and Roger Olsson at Lund University and Linköping University demonstrates injectable monomers that polymerize around the heart, become conductive, and restore normal heart pacing. Testing in zebrafish, this conductive layer is metabolized and degraded in a week without side effects Article available open access at Nature Portfolio https://lnkd.in/eeWdhCkF

Ultrathin, bidirectional, fully-#optical BCIs 💡 Traditional brain implants rely on electrical stimulation and recording. Now, publishing in Nature Electronics, neuroengineers from Columbia University, Yale University, and Rice University led by Eric Pollmann and Ken Shepard developed a thin deep-brain probe containing a dense array of LEDs and photosensors that allows bidirectional optical brain-machine interfacing and optogenetics in small and large animal models. Article at Nature Portfolio: https://lnkd.in/etdv_pk4