New Horizons

The Artificial Intelligence in Infectious Disease Workshop 2024 will take place as a hybrid workshop (allowing both in-person and virtual attendance) in December 2024 in Amsterdam, the Netherlands. This aims to be the catalyst for research dissemination and technology implementation in this rapidly advancing field. To foster conversation and collaborations between our key opinion leaders, innovators, industry experts, and participants, we offer the opportunity to present your research or innovation to your peers! You can find the draft program online here. We will accept both research abstracts and innovation showcases and both formats will be given time within the program via 10-minute presentations, poster sessions. Additionally, we offer exhibition spaces where you can engage with your audience and showcase your services. Below you can read a small description of each. Research Abstracts Research abstracts are concise summaries of academic research that present the key points and findings clearly and succinctly. A research abstract includes an introduction to the problem or hypothesis, a brief description of the methodology used, the main findings or results, and the implications of these findings. Innovation Showcases Innovation showcases highlight practical applications, products, or solutions developed by companies, start-ups, or research labs that utilize artificial intelligence to address challenges in infectious diseases. These presentations often include demonstrations, case studies, or prototypes that illustrate how the technology works and its benefits. The focus is on innovation, practicality, and market readiness, aiming to attract potential collaborators, investors, or users. Should you have any questions, please do not hesitate to reach out! We look forward to reviewing your work and seeing you in December. Topics: Diagnosis and Early Detection Epidemiology and Surveillance Treatment and Management Drug Discovery and Development Prevention and Predictive Analysis Public Health and Patient-Centered Services Digital Equity If you have any research or data related to the application of AI in infectious diseases, we would like to invite you to submit either an encore abstract or potentially new data for presentation at the workshop. This is a great opportunity to share your work with peers and contribute to advancing the field. Deadline: Friday, 4 October 2024 at 23:59 CEST Link to submit: https://lnkd.in/gfvd9gNZ

Types of Supplements Vitamins: These are micronutrients essential for various bodily functions. Vitamins are categorized into two groups: fat-soluble vitamins (such as vitamins A, D, E, and K) and water-soluble vitamins (such as vitamin C and the B vitamins). Minerals: Minerals are inorganic nutrients necessary for physiological functions, such as bone health, nerve function, and fluid balance. Common minerals include calcium, magnesium, iron, zinc, and potassium. Herbal Supplements: These supplements contain plant extracts or botanicals believed to have medicinal properties. Examples include echinacea for immune support, ginseng for energy, and turmeric for its anti-inflammatory properties. Probiotics: Probiotic supplements contain live beneficial bacteria that support gut health and digestion. They may help restore the balance of gut flora and alleviate digestive issues. Fish Oil/Omega-3 Fatty Acids: These supplements provide essential omega-3 fatty acids, such as EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), which are important for heart health, brain function, and reducing inflammation. Protein Supplements: Protein supplements come in various forms, including whey protein, soy protein, and plant-based protein powders. They are commonly used to support muscle growth and recovery, especially by athletes and fitness enthusiasts. Amino Acids: Amino acid supplements provide the building blocks of proteins and are used for various purposes, such as muscle building, athletic performance, and mood regulation. Sports Supplements: These include a range of products designed to enhance athletic performance, improve energy levels, and support recovery. Examples include creatine, caffeine, and electrolyte supplements. Weight Management Supplements: These supplements claim to aid in weight loss or weight management by increasing metabolism, reducing appetite, or blocking fat absorption. Examples include green tea extract, Garcinia cambogia, and conjugated linoleic acid (CLA). Multivitamins/Multiminerals: These supplements provide a combination of vitamins and minerals in one product, aiming to support overall health and fill potential nutrient gaps in the diet. #supplements #minerals #internaltreatment

Phytochemicals (Proposed Action) Types: There are thousands of phytochemicals identified in plant foods, and they can be classified into various groups, including: Polyphenols: This is the largest category of phytochemicals and includes flavonoids, phenolic acids, and lignans. Polyphenols are known for their antioxidant properties. Carotenoids: These pigments give fruits and vegetables their vibrant colors. Examples include beta-carotene, lycopene, and lutein. Glucosinolates: Found in cruciferous vegetables like broccoli, cabbage, and kale, glucosinolates have been studied for their potential cancer-fighting properties. Phytosterols: These compounds are structurally similar to cholesterol and may help lower cholesterol levels in the body. Allyl sulfides: Found in garlic and onions, allyl sulfides may have cardiovascular benefits. Terpenes: Found in herbs and spices, terpenes contribute to their aroma and may have anti-inflammatory and antimicrobial properties. Health Benefits: Phytochemicals have been associated with various health benefits, including: Antioxidant Activity: Many phytochemicals act as antioxidants, helping to neutralize harmful free radicals in the body and reduce oxidative stress. Anti-inflammatory Effects: Some phytochemicals have been shown to have anti-inflammatory properties, which may help reduce the risk of chronic diseases such as heart disease, diabetes, and cancer. Cancer Prevention: Certain phytochemicals have been studied for their potential role in cancer prevention by inhibiting the growth of cancer cells and promoting apoptosis (cell death). Heart Health: Phytochemicals like flavonoids and phytosterols may help lower cholesterol levels, improve blood vessel function, and reduce the risk of heart disease. Brain Health: Some phytochemicals, such as flavonoids found in berries and cocoa, have been linked to improved cognitive function and a reduced risk of age-related cognitive decline. Food Sources: Phytochemicals are abundant in a wide variety of plant-based foods, including fruits, vegetables, whole grains, legumes, nuts, seeds, herbs, and spices. Eating a diverse range of plant foods is the best way to obtain a variety of phytochemicals and maximize their health benefits. #phytochemicals #hearthealth #brainhealth #terpenes #carotenoids

"Fill Your Cup to Overflow Into Others Through Exceptional Self-Discovery and Self-Transformation That Will Create Treasures To Give To Others. A Journey To A Superb Human, Not A Superhuman". - Leone Farquharson, Founder

Probiotics and Prebiotics Probiotics: Probiotics are live microorganisms, typically bacteria or yeasts, that are beneficial for health, particularly for the digestive system. These microorganisms are found naturally in certain foods like yogurt, kefir, kimchi, sauerkraut, and miso, as well as in dietary supplements. Probiotics help maintain a balanced intestinal microbiota by promoting the growth of beneficial bacteria and suppressing harmful microorganisms. They may also play a role in supporting immune function, improving digestion, and synthesizing certain vitamins. Some of the commonly known probiotic strains include Lactobacillus acidophilus, Bifidobacterium bifidum, and Saccharomyces boulardii. Prebiotics: Prebiotics are types of dietary fiber that serve as food for probiotics and other beneficial bacteria in the gut. Unlike probiotics, prebiotics are not living organisms; instead, they are indigestible plant fibers that pass through the digestive system intact. Prebiotics stimulate the growth and activity of beneficial bacteria, thereby enhancing the overall balance of the gut microbiota. Common sources of prebiotics include certain fruits (such as bananas, apples, and berries), vegetables (such as garlic, onions, and asparagus), whole grains, and legumes. In addition to promoting gut health, prebiotics may also have other health benefits, such as improving mineral absorption, reducing inflammation, and supporting weight management. In summary, while probiotics are live microorganisms that confer health benefits when consumed, prebiotics are non-digestible fibers that nourish these beneficial microorganisms. Together, they contribute to a healthy gut microbiome, which is essential for overall digestive health and well-being. #probiotics #prebiotics

Gut-Brain Microbiome Gut Microbiota: The gut microbiota refers to the diverse community of microorganisms, including bacteria, viruses, fungi, and other microbes, that inhabit the digestive tract, primarily the large intestine. These microbes play essential roles in digestion, nutrient metabolism, immune function, and the synthesis of certain vitamins and neurotransmitters. Brain-Gut Axis: The brain-gut axis comprises bidirectional communication pathways between the central nervous system (CNS) and the gastrointestinal tract. This communication occurs through neural, hormonal, and immunological pathways, allowing the brain and gut to influence each other's function and activity. Neural Communication: The vagus nerve, a major nerve that extends from the brainstem to the abdomen, serves as a primary pathway for neural communication between the gut and brain. Signals transmitted via the vagus nerve influence various brain functions, including mood, stress response, and appetite regulation. Neurotransmitter Production: Gut microbes produce and metabolize neurotransmitters and neuroactive compounds, such as serotonin, dopamine, gamma-aminobutyric acid (GABA), and short-chain fatty acids (SCFAs). These compounds can influence mood, cognition, and behavior by modulating neurotransmitter signaling in the brain. Immune System Modulation: Gut microbiota play a crucial role in regulating immune function and inflammation. Dysbiosis, or imbalance in the gut microbiome composition, has been linked to immune-related disorders and neuroinflammation, which may contribute to neurological conditions like depression, anxiety, and neurodegenerative diseases. Metabolic Regulation: The gut microbiome influences host metabolism and energy balance by metabolizing dietary components, producing metabolites, and regulating gut hormone secretion. Dysregulation of metabolic pathways in the gut-brain axis can impact metabolic health and contribute to obesity, diabetes, and metabolic syndrome. Behavioral Effects: Emerging evidence suggests that alterations in the gut microbiota composition (dysbiosis) may affect behavior and mood, leading to symptoms of anxiety, depression, and stress-related disorders. Modulation of the gut microbiome through dietary interventions and probiotics. #behavorialeffects #immunesystem #metabolicregulation #neurotransmitter #neuralinflammation #gutbrainaxis #neuralcomms #gutmicrobiota

Protective Factors Against Risk Factors Affecting Well-Being 1. Positive Parenting 2. Self-Belief 3. Confidence 4. Communication 5. Respectful relations #protectivefactors #protectyourself

Risk Factors Affecting Well-Being Physical Health Conditions: Chronic illnesses, disabilities, or acute health problems can challenge one's well-being by affecting physical functioning, energy levels, and overall quality of life. Mental Health Disorders: Conditions such as depression, anxiety disorders, bipolar disorder, schizophrenia, and others can have a profound impact on well-being, affecting mood, cognition, behavior, and interpersonal relationships. Traumatic Experiences: Exposure to trauma, including physical or sexual abuse, natural disasters, accidents, or witnessing violence, can lead to significant psychological distress and impair well-being. Stressful Life Events: Major life changes such as divorce, job loss, financial difficulties, relocation, or bereavement can increase stress levels and challenge coping mechanisms, affecting overall well-being. Social Isolation and Loneliness: Lack of social support, feeling disconnected from others, or experiencing social isolation can contribute to feelings of loneliness, depression, and decreased overall well-being. Unhealthy Relationships: Toxic or abusive relationships, whether romantic, familial, or social, can have detrimental effects on emotional well-being, self-esteem, and overall happiness. Substance Abuse and Addiction: Misuse of alcohol, drugs, or other substances can lead to addiction, exacerbating mental health issues, impairing judgment, and damaging physical health, all of which impact overall well-being. Financial Strain: Persistent financial difficulties, poverty, or socioeconomic disparities can increase stress, limit access to resources, and negatively impact mental and physical health, thereby affecting overall well-being. Workplace Stress: High-pressure work environments, job insecurity, long hours, lack of autonomy, or conflict in the workplace can contribute to chronic stress, burnout, and diminished well-being. Environmental Factors: Exposure to environmental pollutants, unsafe living conditions, natural disasters, or climate-related events can impact physical health, mental well-being, and overall quality of life. Discrimination and Stigma: Experiencing discrimination or prejudice based on factors such as race, ethnicity, gender, sexual orientation, religion, or disability can lead to psychological distress, reduced self-worth, and diminished well-being. Lack of Access to Healthcare: Limited access to healthcare services, including mental health care, preventive care, and treatment for physical ailments, can hinder well-being by delaying diagnosis, treatment, and support. Poor Nutrition and Lack of Exercise: Unhealthy lifestyle habits, including poor diet, sedentary behavior, and lack of physical activity, can contribute to physical health problems, mental health issues, and reduced overall well-being.

Declining well-being can manifest in various ways, both physically and mentally. Physical Symptoms i. Fatigue: Constant tiredness or lack of energy despite adequate rest. ii. Changes in appetite: Significant increase or decrease in appetite, leading to weight gain or loss. iii. Sleep disturbances: Difficulty falling asleep, staying asleep, or waking up feeling refreshed. iv. Aches and pains: Unexplained headaches, muscle tension, stomachaches, or other physical discomforts. v. Recurrent illnesses: Frequent colds, infections, or other health issues due to a weakened immune system. vi. Emotional and Mental Health Signs: vii.Mood swings: Fluctuations in mood, such as irritability, sadness, anger, or apathy. viii. Anxiety: Persistent worry, nervousness, or feelings of impending doom. viiii. Depression: Persistent feelings of sadness, hopelessness, or emptiness. Decreased motivation: Loss of interest or enjoyment in previously enjoyable activities or hobbies. Difficulty concentrating: Inability to focus, make decisions, or remember things clearly. Increased stress: Feeling overwhelmed, tense, or on edge most of the time. Isolation: Withdrawing from social activities or distancing oneself from friends and family. Increased substance use: Escalation in alcohol, drug, or medication misuse as a way to cope with emotions. Behavioral Changes: Procrastination: Putting off tasks or responsibilities despite negative consequences. Neglecting self-care: Disregarding personal hygiene, grooming, or health maintenance. Avoidance: Avoiding situations, people, or responsibilities that cause discomfort or stress. Impulsivity: Engaging in reckless behaviors without considering the consequences. Relationship difficulties: Strained relationships with friends, family, or coworkers due to mood changes or withdrawal. Decreased productivity: Decline in performance at work, school, or in personal projects. Escapist behaviors: Excessive time spent on distractions like TV, video games, or social media to avoid facing reality. Cognitive Signs: Negative self-talk: Persistent critical thoughts about oneself, abilities, or future prospects. Catastrophic thinking: Exaggerating the potential outcomes of situations, often assuming the worst. Memory problems: Forgetfulness or difficulty retaining information. Lack of creativity: Diminished ability to generate new ideas or solutions to problems. Spiritual and Existential Signs: Loss of meaning: Feeling aimless, purposeless, or questioning the meaning of life. Existential dread: Overwhelming fear or anxiety about death, the unknown, or one's place in the universe. Disconnect from values: Acting in ways that contradict personal values or beliefs. It's important to note that experiencing one or more of these signs doesn't necessarily mean someone is in decline. However, if these symptoms persist and interfere with daily functioning or quality of life, seeking support from a mental health professional or trusted individual is advisable.

Functional Foods Fortified Foods: Many functional foods are fortified with additional nutrients or bioactive compounds to enhance their health benefits. For example, some breakfast cereals are fortified with vitamins and minerals, and certain dairy products are enriched with probiotics or omega-3 fatty acids. Natural Sources of Bioactive Compounds: Some functional foods naturally contain bioactive compounds that contribute to health benefits. For example, fruits and vegetables are rich in antioxidants, which help protect cells from damage caused by free radicals. Examples of Functional Foods: Probiotic Yogurt: Yogurt containing live probiotic bacteria that promote gut health. Omega-3 Enriched Eggs: Eggs from chickens fed a diet rich in omega-3 fatty acids, which may help reduce the risk of heart disease. Fortified Plant-Based Milk: Plant-based milk alternatives fortified with calcium and vitamin D to mimic the nutritional profile of cow's milk. Fiber-Enriched Cereals: Breakfast cereals fortified with extra fiber to support digestive health. Green Tea: Contains polyphenols and antioxidants that may have various health benefits, including reducing the risk of certain diseases. Functional Beverages: Drinks fortified with vitamins, minerals, herbs, or other bioactive compounds, such as vitamin-enhanced water or herbal teas. Regulation: The regulation of functional foods varies by country. In some regions, specific guidelines and regulations govern the labeling and marketing of functional foods to ensure that health claims are supported by scientific evidence. Research and Development: Ongoing research and development in the field of functional foods aim to identify new bioactive compounds and their potential health benefits. This includes studying the effects of phytochemicals, antioxidants, probiotics, and other compounds on various aspects of health. #functionalfood #foodismedicine #insideout