Fantastic share by the @American Cancer Society Journals of this paper by our CureMatch, Inc. founder & colleagues. The average tumor has 5 genomic alterations, and if there are about 700 cancer genes, that means greater than one trillion patterns. This is beyond human cognition, and where #ArtificialIntelligence becomes a critical part of #precisiononcology
Improving outcomes for advanced & metastatic cancers requires a radical change in paradigm. This new #OpenAccess review by Mina Nikanjam, Shumei Kato, Teresa Allen, Jason Sicklick, and Razelle Kurzrock discusses transitioning from drug-centered strategies to patient-centered N-of-1 focus precision in #PrecisionMedicine trials. With greater than 1 × 1012 potential patterns of genomic alterations and greater than 4.5 million possible three-drug combinations, the deployment of artificial intelligence/machine learning may be necessary for the optimization of individual therapy and, in the near future, also may permit the discovery of new treatments in real time. Read the full review, which includes a patient perspective, for free in CA: A Cancer Journal for Clinicians. 🔗 https://lnkd.in/dvQzP7_V MCW Cancer Center UC San Diego Health - Moores Cancer Center