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ecDNA is a fascinating new discovery in the cancer landscape. We'll be watching the field with interest! https://lnkd.in/g-dnnqfG

It's wonderful to see more studies and details about the tumor microenvironment. With the rise of spatial biology, we think this knowledge base will grow exponentially. Lots of data to mine! https://lnkd.in/g_jTWm54

We love tardigrades, and are delighted to see that the mechanisms of their incredible resilience being studied. https://lnkd.in/gsxvREAR

Droplet-based chromatin profiling? Really interesting! https://lnkd.in/ggNuFG68

With the huge and growing amount of sequence information out there, researchers are finding new ways to mine it all the time. In this paper, the group used the marine microbiome for bioprospecting: identifying marine microorganisms with traits that might be useful. They found antimicrobial peptides, enzymes to break down plastic, and a new CRISPR-Cas9 system! https://lnkd.in/gawyYNYS

We don't have access to the journal, but even the abstract is just mind-blowing: some bacteria can respond to a phage infection by reverse-transcribing some non-coding RNA into an ORF that codes for a toxic protein. Crazy stuff! Makes you wonder what else will be found in non-coding DNA and RNA... https://lnkd.in/gKW_G-hD

New rare and ultra-rare genetic variants have been associated with human diseases across ancestry groups-- something that would not have been possible without the rapid, cost-effective sequencing and increased computing power of the modern genomics workflow. We love following the DNA sequencing space for exactly this reason! https://lnkd.in/gRN4GmpJ

A new live attenuated vaccine for COVID is being developed. This one is administered nasally, which would be a great thing for needle-phobic patients as well as induce immunity in the nasal mucosa (which just makes sense). https://lnkd.in/eKNq-F_Y

When the first COVID vaccines were being developed, it was the first time many people had heard of mRNA vaccines. But they'd been in development for some time for other diseases. There's a new clinical trial in the UK for non-small-cell lung cancer! https://lnkd.in/eP_pb4jH

One of the things my team and I are fortunate to witness capturing stories at the edge of technology is just how many talented scientists and engineers are working to create better, more sustainable solutions to the challenges we face today. Mitra Chem is a perfect example of this, as their incredible team works to develop a more sustainable iron-based, North American battery materials supply chain for the EV industry. Thank you Heather Medina and the Mitra Chem team, and Naomi Goumillout, Jenny Nelson, and Christine Rivera of Agilent for the opportunity to help tell Mitra Chem's story. Absolutely amazing work!