Diagnostic Biochips, Inc.

🚨Important Update for DBC Product Sales🚨 Effective immediately, Cambridge NeuroTech, will be the lead on all future sales and support of the Deep Array probes that you have been using. The Deep Array manufacturing will still take place on site at the DBC lab, so the same quality and attention to detail that you trust will remain intact! This important change will enable us to restructure and turn our focus toward continued development of cutting-edge neurotechnology tools to support both the basic research and clinical arenas. All inquiries to receive quotes can be sent to info@cambridgeneurotech.

Did you know your brain simulates movements and interactions while you sleep? During REM sleep, even without physical movement, your brain issues motor commands, shifting your internal sense of direction as if you were awake. The Scanizani Lab at UCSF determines how it works: Takeaways: 🌙 Your brain sends motor commands during dreams that create a sense of action, even though your body is still. 🌙 Head direction cells, which track real-world direction, continue to shift in dreams, creating "virtual" movement. 🌙 Motor commands during REM sleep mimic the brain patterns of real-world movements, making dreams feel vivid and lifelike. REM sleep allows the brain to test out scenarios and rehearse actions, all while we dream. This research could help explain why our dreams feel so vivid and realistic, even when we're completely disengaged from the outside world. Read the full study: https://hubs.ly/Q02PJf0-0 #DBCInside #Neuroscience #Electrophysiology

🧪📚 With school back in session, now’s the perfect time to stock up on DBC probes for your research students! Equip your lab with the best tools for success and explore our most competitive pricing yet. Order in bulk and save even more! https://hubs.ly/Q02NDsm70 #Ephys #Neuro

Memory Consolidation in Action: A New Network Discovery in Science from Cornell University! Researchers have uncovered a novel event that helps maintain brain stability during memory consolidation. After learning, hippocampal cells increase their firing during sleep sharp-wave ripples (SWRs), reinforcing recent experiences. But how does the brain prevent runaway activity and return to baseline levels? Introducing BARRs (barrage of action potentials)—a newly identified network event! During NREM sleep, specific hippocampal cells (CA2 pyramidal cells and CCK+ basket cells) fire intensely, temporarily silencing the neurons active during learning. The SWRs active after learning in NREM sleep are anti-correlated with BARRs to stabilize memory and prevent overactivity. What happens when BARRs is disrupted? Memory consolidation falters, showcasing how vital these events are to healthy brain function! This neural network is a general mechanism across multiple types of species and memory tasks. BARRs contribute to our body's system of achieving homeostasis. This new understanding could lead to more research in unlocking the unknowns of memory disorders. Read the full study: https://hubs.ly/Q02MN82s0 #DBCInside #Neuroscience #Electrophysiology

🧠 New study using DBC Deep Array from Christopher Fetsch's lab at Johns Hopkins University reveals how monkeys form decisions and confidence simultaneously. 🧠 Key Findings: * Neural Insights: Activity in the lateral intraparietal area (LIP) of the brain shows that both choice and confidence are updated together, highlighting a sophisticated, parallel processing system. * Behavioral Evidence: The task allowed us to measure choice and confidence simultaneously, confirming that monkeys can make provisional confidence assessments in sync with their decisions. This research provides a clearer picture of how decision-making and confidence are intertwined, offering valuable insights into the neural mechanisms of metacognition. #Neuroscience #Electrophysiology #DBCInside Read the full study: https://hubs.ly/Q02LXVL40

🧠 Exploring the Brain's Response to Environmental Changes: A Deep Dive into Norepinephrine (NE) Dynamics New research reveals how our brain's memory systems are shaped by environmental changes. When we encounter something unexpected, our brain's NE levels spike, potentially helping us segment memories and create lasting impressions. Using cutting-edge technology, scientists at University of New Mexico and Virginia Tech have measured NE release in the hippocampus of mice, uncovering how these dynamics unfold. 🔍 Key Findings: - NE release in the hippocampus aligns with moments of environmental change, helping encode different experiences. - Familiar environments accelerate the return of NE to baseline levels after changes. - Unique patterns of neural activity are observed right after these level transitions, potentially aiding long-term memory. 💡 Why it Matters: Understanding NE's role in memory formation could provide insights into cognitive disorders like ADHD, Alzheimer's, and PTSD. This research highlights the importance of how our brains reset and reorganize after encountering new experiences, laying the groundwork for future studies on memory and attention. Read the full study: https://hubs.ly/Q02KG5m40 #DBCInside #Electrophysiology #Neuroscience

🧠 📈 Neurotech News #3: Macro-Neuro-Tech has been published! 📈 🧠 In this issue we will zoom out and take a look at some macro-level trends in neurotech including:  - Convergence of BCI and neuromodulation ⚡️ 💻  - Business of BCI 💰 📊 - New Neurotech Startups Emerging 😎🎆 - Dynamic Neurotech Podcast Launch 🚀 🌙 Click the link below to give it a read and make sure to SUBSCRIBE so you don’t miss out on future updates, research, and analysis. https://lnkd.in/eNFkzTwR

Researchers around the world are delving deep into the brain, exploring Parkinson's Disease at the single-unit level. This means they're studying individual neurons to uncover how Parkinson's affects brain function. Identifying motor and cognitive patterns in a healthy vs. disease-affected brain allows scientists to answer the questions that still remain about this serious disease. Our customers and many other neuroscience labs aim to understand Parkinson's at the cellular level with hopes to apply their findings to drug development and possible cures. Link to Parkinson's Foundation: https://hubs.ly/Q02JgnBl0

Cell Press recently published the research from Dr. Kari Hoffman's lab. Sam Abbaspoor and Kari Hoffman utilized the DBC Deep Array to uncover the systems of cells in the deep layers of macaque hippocampus. They reveal how its unique circuit dynamics govern navigation, memory, and social behaviors across species. Key insights: 🧠 Pyramidal cells, organized into distinct layers, receive unique inputs and exhibit specialized response patterns. 🧠 Inhibitory cells play a crucial role in regulating pyramidal cell dynamics and network oscillations. 🧠 These interactions are essential for memory and navigation, and have implications for understanding diseases like epilepsy and schizophrenia. Read the full study here: https://hubs.ly/Q02H7CJp0 #DBCInside #Neuroscience #Electrophysiology