EpicentRx, Inc.

It's already the end of July - how time does fly!   The unquestioned highlight of Q2 - and possibly of all 2024 - was the BOOM heard 'round the world from Dr. Anthony Conley's ASCO oral presentation on the transforming growth factor beta (TGFß) inhibitor, AdAPT-001. Other Q2-worthy news: enrollment continues for the two ongoing late-stage RRx-001 clinical trials, Phase 3 REPLATINUM and the Phase 2b KEVLARx in radioprotection.   Meanwhile, Q3 is off to a great start with several promising networking and business development opportunities, the award and submission of new grants, and top-tier conferences like the Society for Neuroscience (SIN) where EpicentRx will present.   Stay up to date here: https://bit.ly/4c5021y. 

Wake up and smell the #nostalgia - and the #popcorn. We fondly remember the Blockbuster Video retail chain from the 1980s and 1990s that went extinct over a decade ago (except in Bend, Oregon where the last Blockbuster standing, a novelty shop and relic of a bygone era all in one, is located) after the introduction of digital streaming services like #Netflix, #Amazon, and #Hulu that rendered the Blockbuster business model obsolete. Lead EpicentRx therapy, #RRx001 (#nibrozetone) tries to adhere to the “be kind, rewind” message that was always found inside of every Blockbuster VHS case. This is because RRx-001 potentially acts to reverse or rewind the symptoms and pathology associated with several diseases like #cancer, #severeoralmucositis, #xerostomia, #endometriosis, #Parkinsons and #ALS or #MND. Read more in this “new release” blog post here: https://bit.ly/4g6XJh9. 

Since chronic and sometimes fatal conditions like cancer, severe oral mucositis, endometriosis, and neurodegenerative diseases put the scare into us all year round, we thought to return the favor with these post-Halloween “misfortune cookies.” Break them open here to discover what grim fate awaits these conditions: https://bit.ly/3rAZ2RG. 

#FortKnox in Kentucky is synonymous with gold bullion. Fort NOx aka #RRx001 (#nibrozetone) which releases therapeutic nitrogen oxides (NOx) in the vicinity of diseased tissues, is synonymous with #platinum. In two clinical trials, the Phase 3 REPLATINUM and the Phase 2b KEVLARx, RRx-001 is paired with carboplatin and cisplatin, respectively, given its potential to make them more active and less toxic. Read more here in this blog post: https://bit.ly/3ULS9IA.

Boxer Mike Tyson refers to himself as a “natural born killer” and his opponent, YouTuber Jake Paul, as a “manufactured killer.” Lead EpicentRx therapy, AdAPT-001, is both. Read more in this blog here: https://bit.ly/3ULQT8c. 

Hurray, it’s today. Learn more at #SITC24. This is a must-see SITC. Visit Anthony Conley at his poster presentation on the remarkable clinical synergy between #AdAPT001 and checkpoint inhibitors. Be there or be, not square, but the shape of the poster. Click here: https://bit.ly/4fyILzS. 

Hurray, it’s today. Learn more at #SITC24. This is a must-see SITC. Visit Anthony Conley at his poster presentation on the remarkable clinical synergy between #AdAPT001 and checkpoint inhibitors. Be there or be, not square, but the shape of the poster. Click here: https://bit.ly/4fyILzS. 

According to up-and-coming NASCAR star, Ricky Bobby, from the comedy, Talladega Nights, “If you ain’t first, you’re last.” The motto of lead EpicentRx therapy, AdAPT-001, could well read instead, “If you ain’t first, the response will last” meaning that it takes time to reprogram immune cells and to activate a durable antitumor response. Read more here in this blog: https://bit.ly/4efV5UJ. 

#ElonMusk has railed repeatedly against “the woke mind virus.” The only “woke virus” that Elon would approve of is lead EpicentRx therapy, AdAPT-001. This virus wakes up the dormant immune system with its transforming growth factor beta (TGFβ) trap to attack tumors. #wokevirus #antitumorimmunity: https://bit.ly/4egKxVl.

Much in the news of late, word salads are a jumbled mix of confusing croutons, logicless lettuce, and radishes of redundancy, all drizzled with a dollop of doubtful dressing. Lead EpicentRx therapy, AdAPT-001, delivers a non-word salad to tumors in the form of short, to-the-point commands, written in the concise language of DNA, which causes them to regress and, even in some cases, to disappear. Read more here: https://bit.ly/3YtKOOP.