Expression Systems

“We are proud to share our latest sustainability report, which not only highlights our significant progress but also reflects the core values that guide every decision we make at Advancion. As a leading global producer of specialty ingredients, we recognize our responsibility extends beyond delivering innovative solutions—we must also address the environmental, social and economic challenges of our time. This report underscores our progress and our dedication to driving positive changes across the markets and communities we serve. Our goal is clear: to deliver long-term value for our customers, employees and communities while safeguarding the health of our planet. We remain focused on accountability, transparency and continuous improvement as we work toward a more sustainable future for all our stakeholders.” https://lnkd.in/gS9_qBeG #sustainability #CSR #ESG #GRI #transparency #committment #accountability

Accurate titering of recombinant baculovirus is an essential step in protein production optimization. Our unique expertise in the baculovirus expression vector system (BEVS) enables us to help researchers and clinicians work at the highest level of consistency and productivity. As part of our baculovirus titering service, we utilize a high throughput, flow cytometric assay to quantitate infectious baculovirus particles produced in insect cell culture, allowing for accurate virus titer determination in less than 24 hours. Contact us to learn how Expression Systems has helped other leading institutions maximize expression and reproducibility with our quick and accurate titering service for recombinant baculovirus. #BEVS #AAV #biopharma #vaccines #cellandgenetherapy https://lnkd.in/guNgHMcY

"We are incredibly proud to once again earn the EcoVadis Gold Medal for sustainability performance in 2024. This recognition not only reflects our unwavering commitment to sustainable practices, but it is also a testament to the dedication of our team to creating a positive impact on the environment and society. Achieving this milestone is crucial as it independently validates our efforts to operate responsibly as well as enhances stakeholder trust and aligns with our global sustainability goals. We will continue to strive for excellence in sustainability, driving positive change in our industry and beyond.” https://lnkd.in/gujrXx5E #sustainability #corporatesocialresponsibility #continuousimprovement #commitmenttoexcellence

Expression Systems’ Production Boost Additive (PBA) is a proprietary nutrient supplement specifically designed to enhance cell culture production after the establishment of baculovirus infection. PBA works to increase protein expression by supporting the enhanced needs of insect cells infected by recombinant baculovirus and grown in ESF 921 or ESF AF cell culture media. PBA can be used for supplementation at a rate of 1–10% at 6–36 hours post infection and has been demonstrated to improve protein expression yields by up to 4x.   - Serum-free, animal-free formulation works seamlessly with ESF 921 and ESF AF cell culture media formulations - Extends culture period by maintaining cell viability - Available in 100 mL or 1 L bottles   Contact us today to purchase a bottle and see for yourself how our PBA can increase your protein expression! https://lnkd.in/gHRgrb_v   #AAV #bioproduction #biopharma #biopharmaceutical #pharma #biotech #BEVS #baculovirusexpression #viralvectors #advancedtherapies #cellandgenetherapy #advancedtherapymanufacturing

Our next-generation, scalable BEVS manufacturing platform was specifically designed to enhance productivity and streamline regulatory approvals for the production of AAV gene therapies and VLP vaccines, by delivering: – High productivity – exceptional cell growth and expression yields – Robust process and scale-up consistency – 100% chemically defined media – Risk mitigation – rhabdovirus-free cell line removes known adventitious agent – Streamlined regulatory approvals – complete documentation and cell line traceability This proprietary platform combines our Sf9 RV-Free rhabdovirus-free cell line and ESF AdvanCD™ chemically defined insect cell culture medium to achieve exemplary cell growth (viable cell densities >25 million per mL), impressive expression yields (as much as 5x the competition), and a greatly improved biosafety profile. Find out for yourself by ordering our Promo Pack, which is available for a limited time only and includes one vial of Sf9 cells, four one-liter bottles of ESF AdvanCD™ media, and one 20 ml bottle each of virus stabilization additive and transfection medium –  a $1,200 value for only $400! https://lnkd.in/dCY6Jiyz #AAV #VLP #vaccines #molecularbiology #bioproduction #biopharma #biopharmaceutical #pharma #biotech #BEVS #baculovirusexpression #viralvectors #advancedtherapies #cellandgenetherapy #advancedtherapymanufacturing

We’re looking forward to participating in the upcoming Korea Society of Biochemistry and Molecular Biology (KSBMB) International Conference 2024 together with our distribution partner, EG Biotech. If you’re attending the event, we invite you to stop by stand No. 1F-9&10 at BEXCO in Busan, Korea from May 29-30 to learn more about THE gold standard in baculovirus expression vector system (BEVS) workflow tools for structural biology applications, including ESF 921 insect cell culture media, insect cell lines, and molecular reagents.  While you’re there, don’t forget to ask about our recently launched next-generation BEVS manufacturing platform, which offers exceptional cell growth and expression performance for the production of recombinant proteins, adeno-associated virus (AAV) vectors, and virus-like particles (VLPs)! Not attending the event and want to learn more? Visit expressionsystems.com  #cellculturemedia #LifeSciences #AAV #biologics #BEVS #structuralbiology #lifesciences #bioprocessing #ESF921

Looking for a high-performance, cost-effective way to scale up protein production for structural biology or AAV (adeno-associated virus) applications? Expression Systems and Thomson Instrument Company recently teamed up to demonstrate how the combination of Expression Systems new ESF AdvanCD™ cell culture medium and Thomson Optimum Growth® flasks offers an effective solution for scaling up protein production utilizing baculovirus and insect cell expression platforms. In addition to highly consistent cell growth, exceptional expression levels were observed between various flask sizes and culture volumes, providing confidence in a robust and scalable platform. To learn more, check out our recently published application note https://lnkd.in/gs_xhJvz detailing the cultivation of Sf9 suspension cells using ESF AdvanCD chemically defined cell culture media together with Thomson Optimum Growth flasks. #LifeSciences #AAV #biologics #BEVS #celltherapy #genetherapy

It was great to be back at last week’s BioProcess International (BPI) US West Conference where we featured Expression Systems’ newly developed manufacturing platform for the production of adeno-associated virus (AAV) vectors, virus-like particles (VLPs), and recombinant proteins. If you didn’t attend the event or weren’t able to connect with the Advancion and Expression Systems team while you were there, don’t miss out on the opportunity to learn how our manufacturing platform can enhance productivity and streamline regulatory approvals for your clinical programs.   Contact us today at orders@expressionsystems.com to request a copy of our technical poster, “A Rhabdovirus-free Sf9 Cell Manufacturing Platform for Biologics,” for a firsthand look at new and exciting data on the documented monoclonality of our rhabdovirus-free cell line and the exceptional performance provided by our new AdvanCD™ chemically defined insect cell culture media. #Bioprocessing #BPIWest #LifeSciences #AAV #biologics #BEVS

The Advancion and Expression Systems team will be at the upcoming BioProcess International US West Conference in San Diego, CA from March 11-14 (Booth #122) where we will feature our biological buffers, contract services, and our newly developed scalable manufacturing platform for the production of adeno-associated virus (AAV) vectors, virus-like particles (VLPs), and recombinant proteins.    During the event, don’t miss our technical poster, Rhabdovirus-free Sf9 Cell Manufacturing Platform for Biologics (poster #34), which presents exciting data on the documented monoclonality of our rhabdovirus-free cell line and the exceptional cell growth and expression performance in our new AdvanCD™ chemically defined insect cell culture media.   Unable to attend and want to learn more? Visit our website for more information or contact us at sales@expressionsystems.com.  https://lnkd.in/gnn548vv #Bioprocessing #BPIWest #LifeSciences #AAV #biologics #BEVS

We’re excited to participate in the upcoming BioProcess International US West, March 11-14, in San Diego, CA. Visit our experts in booth 122 to learn more about our new, scalable BEVS manufacturing platform comprised of ESF AdvanCD™ chemically defined insect cell culture medium, BestBac™ linearized baculovirus DNA backbone, and Sf9 RV-Free rhabdovirus-free insect cells. Expression Systems' RV-Free cell line and AdvanCD media platform demonstrate exemplary cell growth (viable cell densities in excess of 25 million per mL) and productivity. Together with rBV constructed with BestBac, this scalable upstream manufacturing process is ideal for improving process efficiencies while maintaining product quality in AAV vector production. #Bioprocessing #BPIWest #LifeSciences #AAV #biologics #BEVS https://lnkd.in/gnn548vv