Helix Biostructures

Time flew fast at the American Crystallographic Association's 74th Annual Meeting in Denver, Colorado last week (July 7-12, 2024) ( https://loom.ly/OCLftGM ). What a fantastic event! The speakers, sessions, and topics were incredibly informative and relevant, offering valuable insights across the board. The posters were equally impressive, showcasing cutting-edge research and innovations. Mr. Carter thoroughly enjoyed reconnecting with old colleagues and meeting new ones, engaging in highly stimulating conversations throughout the event. Both he and Helix are excited to attend again next year, looking forward to another year of learning and networking! Our Cryo-EM and X-ray services can help you gain the insights you need into the structural details of your biological entity of interest, whether wild-type or mutated. Call us today and get the results you need! (https://loom.ly/WvpvryM) #cryoem #crystallization #crystallography #drugdiscovery #drugdesign #protein #proteins #dna #rna #antibody #antibodies #science #nature #research #bio #bionetwork #biotechnology #biotech #bioscience #biotechnologyindustry #biopharma #drugdesign #drugdevelopment #pharmaceuticals #pharma #drug #lifesciences #lifescience

Helix's CEO, Josh Carter, is participating at the American Crystallographic Association's 74th Annual Meeting in Denver, Colorado, from July 7-12, 2024. Day 4 has been filled with valuable networking opportunities and insightful presentations in areas such as protein flexibility and drug design, data analysis for structural elucidation, and MicroED for small molecules. Two fantastic presentations included “Structure Determination of Difficult to Grow Active Pharmaceutical Ingredients (APIs) using MicroED” by AbbVie, and “Structure determination by NMR Crystallography, from microcrystalline powders to amorphous molecular solids” by EPFL (Switzerland). And the poster sessions also continue to showcase groundbreaking research! If you are at the conference, Josh would be delighted to connect, discuss science, and exchange insights. He looks forward to sharing how his and Helix's expertise excels in overcoming challenges and advancing projects. Did you know that our Cryo-EM and X-ray services can help you gain unprecedented insights into the structural details of your biological entity of interest, whether wild-type or mutated? Call us today and get the peace of mind you deserve! (https://loom.ly/S6ImyLI) #cryoem #crystallization #crystallography #drugdiscovery #drugdesign #protein #proteins #dna #rna #antibody #antibodies #science #nature #research #bio #bionetwork #biotechnology #biotech #bioscience #biotechnologyindustry #biopharma #drugdesign #drugdevelopment #pharmaceuticals #pharma #drug #lifesciences #lifescience

Helix's CEO, Mr. Josh Carter, is actively engaging at the American Crystallographic Association's 74th Annual Meeting in Denver, Colorado, from July 7-12, 2024. Day three has been electrifying, featuring an array of exciting and highly relevant topics such as MicroED, Cryo-EM, and Structural Biology in Pharma/Biotech. Two great talks that highlight the intersection of various disciplines, including crystallization, docking, and targeting undruggable proteins, are "Novel Fragment Inhibitors of PYCR1 from Docking-Guided X-ray Crystallography" from U. Missouri, ChemSpace, and Taras Shevchenko National University of Kyiv, and "Branched Chain Ketoacid Dehydrogenase Kinase Inhibitors: From Fragments to Clinical Candidate" by Pfizer. And don’t miss the poster sessions, which are also full of groundbreaking research! Mr. Josh Carter looks forward to connecting with both familiar and new friends, clients, and colleagues, sharing Helix's contributions and insights on today's topics in these fields. Be sure to catch up with him! Did you know... Our leading Cryo-EM services, together with our extensive expertise, consistently fuel the success of our clients and their projects? Empower projects with Helix and Cryo-EM. Call us today! (https://loom.ly/SNcIRks) #cryoem #crystallization #crystallography #drugdiscovery #drugdesign #protein #proteins #dna #rna #antibody #antibodies #science #nature #research #bio #bionetwork #biotechnology #biotech #bioscience #biotechnologyindustry #biopharma #drugdesign #drugdevelopment #pharmaceuticals #pharma #drug #lifesciences #lifescience

Helix's CEO, Mr. Josh Carter, continues his participation at the American Crystallographic Association's 74th Annual Meeting in Denver, Colorado, from July 7-12, 2024 ( https://loom.ly/OCLftGM ). The second day has been fantastic, with morning and afternoon sessions covering topics in structural sciences, Cryo-ET, and Hot Structures, to name a few. Two standout talks include “Unveiling the Molecular Interplay of VPS34 Inhibition by Novel Drug Targets: A Promising Approach for Tailored Cancer Therapeutics” from Brigham Young University, and “Development of Constructs and Crystal Forms of HSP47 to Support Structure-Based Drug Design” by Bristol-Myers Squibb. The day is packed with phenomenal sessions, and our CEO, Mr. Josh Carter, is eager to connect with both old and new friends, clients, and colleagues for meaningful conversations about today’s topics and overcoming challenges in these fields. Be sure to look for him! Did you know... Our gene-to-protein expression, isolation, crystallization, and structural determination services are crucial for the success of many projects? Our clients rely on us to deliver the quality results they need to achieve their goals. Contact us today and let us help you achieve your goals! (https://loom.ly/tDP9lr8) #cryoem #crystallization #crystallography #drugdiscovery #drugdesign #protein #proteins #dna #rna #antibody #antibodies #science #nature #research #bio #bionetwork #biotechnology #biotech #bioscience #biotechnologyindustry #biopharma #drugdesign #drugdevelopment #pharmaceuticals #pharma #drug #lifesciences #lifescience

Exciting read alert! Obtaining crystal structures of membrane proteins is no easy task, making this review essential. Membrane proteins play crucial roles in various physiological processes, and understanding their 3D structures is vital for insights into their functions and drug discovery. X-ray crystallography remains the primary method for determining these structures, despite challenges in protein extraction, solubilization, stabilization, and crystallization ( https://loom.ly/F1JijyM ). This review offers a comprehensive guide from protein extraction to structure determination, covering pre-crystallization screening methods and strategies to enhance crystallization success. Enjoy this invaluable, free resource for solving membrane protein structures! Did you know... Our protein expression, purification, crystallization, and structure determination services are the key to the success of many projects? Our clients trust us to deliver the quality results they need to achieve their goals. Contact us today and let us help you take your project to the next level! (https://loom.ly/pWCRgGg) #cryoem #crystallization #crystallography #drugdiscovery #drugdesign #protein #proteins #dna #rna #antibody #antibodies #science #nature #research #bio #bionetwork #biotechnology #biotech #bioscience #biotechnologyindustry #biopharma #drugdesign #drugdevelopment #pharmaceuticals #pharma #drug #lifesciences #lifescience

The impact of Cryo-EM on structureomics is tremendous, and this review offers an informative overview. Structureomics aims to create a comprehensive 'structureome,' detailing molecular models for nearly every protein across various genomes ( https://lnkd.in/gtYzZDW8 ). While experimental validation and accounting for dynamic protein structures are necessary, the structureome provides a deeper understanding of cellular states beyond gene sequences or expression levels. This advancement is revolutionizing structural biology, allowing researchers to explore molecular intricacies with unparalleled precision. Read this article… it's freely accessible! Did you know... our cutting-edge Cryo-EM services, alongside our exceptional expertise, are the key factors behind our clients' continuous project successes? Revolutionize projects with Helix and Cryo-EM. Call us! (https://loom.ly/XFNYiNI) #cryoem #crystallization #crystallography #drugdiscovery #drugdesign #protein #proteins #dna #rna #antibody #antibodies #science #nature #research #bio #bionetwork #biotechnology #biotech #bioscience #biotechnologyindustry #biopharma #drugdesign #drugdevelopment #pharmaceuticals #pharma #drug #lifesciences #lifescience

Get your research into Nature with Helix! ✅ Samples prepared, collected, and processed by Helix BioStructures ✅ 100s of Citations, multiple years running Contact us today: https://loom.ly/7IkoNh4

The Helix team is expanding! So fast in fact, that we need a Lab Operations Manager: This role will manage and support the Helix team, planning & tracking all projects to produce high-quality work and support our client’s protein production, biophysical characterization, and structural biology projects. A proven track record in managing people and projects with a deep understanding of protein construct design, expression, and purification of challenging proteins, biophysical characterization, and structural biology techniques is essential. See more & Apply Here: https://loom.ly/gWaH2RY

As we embark on the final day of the Structure-Based Drug Design Summit, the sentiment of awe and inspiration continues to resonate throughout the conference halls ( https://lnkd.in/gdeMB-Tr ). This event has truly been nothing short of amazing, surpassing all expectations and leaving an indelible mark on all who have participated. As a proud Exhibition Partner, Helix couldn't be more honored to have been a part of such an extraordinary gathering of minds and ideas. From the enlightening presentations to the fruitful networking opportunities, every moment has been a testament to the remarkable advancements and collaborative spirit within the field of drug design. As the conference draws to a close, we're already looking forward to the next opportunity to reunite with this vibrant community and continue our shared journey of innovation and discovery. Until next time, Boston… we'll be back! Did you know… We offer integral Cryo-EM and x-ray services that elucidate critical structural details crucial for the success of your projects, including proteins, antibodies, RNA, and biologicals? Leverage our extensive expertise to propel your project to the finish line. (www.HelixBioStructures.com) #cryoem #crystallization #crystallography #drugdiscovery #drugdesign #protein #proteins #dna #rna #antibody #antibodies #science #nature #research #bio #bionetwork #biotechnology #biotech #bioscience #biotechnologyindustry #biopharma #drugdesign #drugdevelopment #pharmaceuticals #pharma #drug #lifesciences #lifescience

As we dive into Day 2 of the Structure-Based Drug Design Summit here in vibrant Boston, MA, the enthusiasm is still at its peak! ( https://loom.ly/hZpYijk ) The conference is exceeding all expectations, with each session brimming with insightful presentations, engaging exhibitions, and invaluable networking opportunities. Day 2 is shaping up to be particularly thrilling, with a lineup of presentations that promise to delve deeper into the latest advancements and cutting-edge research in the field. As we reach the halfway mark of this dynamic 3-day event, it's evident that the momentum is only building, and we're loving every minute of it. The atmosphere is buzzing with excitement, and we can't wait to see what the rest of the conference has in store! Did you know... With our Cryo-EM and x-ray crystallization services, clients can uncover the structural shape and attributes of their proteins, antibodies, and other biologicals? Success is the outcome of combining capability, capacity, and expertise. Contact us today to learn how we can help drive the success of your project. (www.HelixBioStructures.com) #cryoem #crystallization #crystallography #drugdiscovery #drugdesign #protein #proteins #dna #rna #antibody #antibodies #science #nature #research #bio #bionetwork #biotechnology #biotech #bioscience #biotechnologyindustry #biopharma #drugdesign #drugdevelopment #pharmaceuticals #pharma #drug #lifesciences #lifescience