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InvivoGen

InvivoGen

Biotechnology Research

San Diego, California 7,854 followers

INNOVATION WITHIN REACH

About us

At InvivoGen, we strive to provide life scientists worldwide with innovative, high quality and reliable reagents. As specialists in cell culture engineering and innate immunity, we are passionate about designing, developing, and bringing to market new tools and services for cutting-edge research. At our three regional headquarters — in Toulouse (France), San Diego (USA) and Hong Kong (China) — and through our dedicated multilingual customer support staff, we can provide researchers around the globe with the reagents and product information that they need to make the scientific breakthroughs of tomorrow. InvivoGen is a privately held company founded by university researchers in 1977 in Toulouse, France. Since then, we have gradually expanded with the opening of InvivoGen San Diego, in 1997, and InvivoGen Hong Kong, in 2014. Our unparalleled skills in microbial fermentation enable us to produce a wide range of bioactive molecules, including ultra-pure antibiotics, novel mycoplasma treatments and the largest available collection of pattern recognition receptor agonists, from various micro-organisms. Over 25% of InvivoGen’s employees hold a PhD in biology or chemistry. Through specialized R&D teams, they work together seamlessly to design, produce and validate novel plasmids, cell lines, vaccine adjuvants and synthetic ligands for research in areas as diverse as gene therapy, molecular immunology and vaccination. Moreover, based on our first-hand knowledge of innate immune receptor signaling pathways, we have devised an ever-expanding collection of reporter cell lines, including cytokine reporter cells and knockout (KO) cell lines for high-priority innate immune targets. Scientists depend on InvivoGen for quality, consistency and reliability. Whatever research challenges you are facing, count on InvivoGen to provide you with the tools and solutions that you need.

Industry
Biotechnology Research
Company size
51-200 employees
Headquarters
San Diego, California
Type
Privately Held
Founded
1977
Specialties
Research Reagents, Innate Immunity, Gene Therapy, IgA, Fermentation, Monoclonal Antibodies, Molecular Biology, Vaccine Adjuvants, Cell Culture, Selective Antibiotics, TLR Ligands, PRR Ligands, Nucleic Acid Sensing, cGAS/STING, Interferon Pathways, LPS, and Transfection

Locations

Employees at InvivoGen

Updates

  • Did you know what you eat impacts your productivity at work? At InvivoGen, we believe employee well-being starts with knowledge, balance, and health. So last week, our HSE & CSR teams turned nutrition into a fun challenge through a Kahoot quiz! 🎉 🔍 Why Nutrition? What we eat directly impacts our energy, focus, and overall health. So, we turned learning into a game, mixing fun, friendly competition, and useful tools for everyday life! 🎯 How It Worked: Smartphone-based quiz – Fast, engaging, and interactive Live discussions 💬 – Every question sparked an exchange of scientific insights and practical tips 🔎 Topics covered: - How to read food labels  - The hidden risks in processed foods  - The truth about sugar consumption  - Balancing macronutrients for energy & health Because a healthier team is a happier & more innovative team! 🤝 What’s one small change in your diet that made a big impact on your energy levels? Share below! 👇💬 #EmployeeWellBeing #Nutrition #Health #WorkplaceWellness #HSE #Sustainability #CorporateCulture #FoodScience #HealthyLiving

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    📈 Enhancing Tumor Suppression with TLR7/8 Agonists & IFN-I Can we boost systemic anti-tumor immunity with a targeted combination therapy? A recent study (PMC11779648) reveals that systemic Type I Interferons (IFN-I) combined with topical TLR7/8 agonists can trigger distant tumor suppression, offering a promising avenue for next-generation immunotherapies. How does this work? - TLR7 agonist Imiquimod & TLR8 agonist R848 activate dendritic cells - This induces c-Jun-dependent IL-12 expression, enhancing anti-tumor responses - Proven effective in the B16OVAmb model Why does this matter? ✔ Expands IFN-I therapeutic potential in immuno-oncology ✔ Enhances tumor-specific immunity through IL-12 expression ✔ Strengthens systemic responses against distant tumors Are you working on TLR-based immunotherapies ? 🥼  📢 Contact us if you are interested in any of these innovative research tools!🛠 #ImmunoOncology #TLR7 #TLR8 #CancerResearch #DendriticCells #TumorImmunity #Biotech #ScientificResearch #CellCulture #InvivoGen

  • Boost Your Research with InvivoGen’s TLR & NOD Tools! 🛠 Explore our comprehensive range of tools to study Toll-like receptors (TLRs) and NOD1/NOD2. From agonists and antagonists to antibodies, inhibitors and cell lines, all our products are FUNCTIONALLY TESTED and FREE OF UNWANTED BACTERIAL CONTAMINANTS. With InvivoGen, you get high-quality reagents designed to save you time, money, and effort. 🥼 #InvivoGen #PRR #Biotech #InnateImmunity #TLRs #NOD1NOD2 #Immunology #BiomedicalResearch #Reagents

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  • 🧫 How to Keep Your Cell Culture Contamination-Free? 🧫 Contamination in cell culture is a silent killer 🤫 Bacterial, fungal, and mycoplasma infections can ruin weeks of hard work, leading to unreliable data and lost productivity. But what if you could eliminate contamination risks before they even start? Meet Normocin & Primocin, the ultimate protection for your cultures 🛡 👉 Normocin: Broad-spectrum antibiotic targeting bacteria, mycoplasma, and fungi, ensuring long-term contamination control. 👉 Primocin: Specifically designed for primary cells, eliminating bacterial and mycoplasma contamination without affecting cell viability. Why does this matter for your lab? ✔ Say goodbye to contamination-induced failures ✔ Reduce time wasted on decontamination efforts ✔ Ensure reproducible, high-quality experimental data 📢 Want to know which antimicrobial agent fits your research? Comment below or contact us to discuss your projects 🥼🔬 #CellCulture #Biotechnology #Immunology #ScientificResearch #LabLife #Innovation #ContaminationControl #Antibiotics

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    🧫 Dennis is at Fred Hutch helping fuel cancer research today! 🧰 Our expansive toolbox of high-quality reagents and services help make extraordinary discoveries possible for so many scientists. 🔎 Discover innovation within reach: https://lnkd.in/eBZf4pRU 📍 Fred Hutch Weintraub Building  📅 Tuesday, March 4 🕐 11:00am - 1:00pm PST #ScientificProductShow #InvivoGen #InnateImmunity #ScientificResearch #CancerResearch #ResearchInnovation #Biotechnology #Immunotherapy #Immunology

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  • Mycoplasma: The Silent Threat in Cell Culture 🤫 Think your cell cultures are safe? Think again. Up to 35% of labs unknowingly work with mycoplasma-contaminated cultures, and the impact is bigger than you think. What Makes Mycoplasma So Dangerous? Unlike bacteria and viruses, mycoplasma are small, sneaky & stubborn: 🦠 No cell wall → Resistant to many antibiotics 🦠 Too tiny for standard microscopes → Spreads undetected 🦠 Doesn’t kill cells immediately → But slowly disrupts their function Why Should You Care? Contaminated cultures don’t always look different, but they silently sabotage your research ❌ - Slower cell growth - Reduced protein production - Altered gene expression → Leading to unreliable results The worst part? Most researchers don’t detect it until it’s too late. 🧐 Early detection & prevention are key! 🗝 ✔ Regular mycoplasma detection keeps your cultures safe ✔ Specialized antibiotics can prevent or eliminate contamination ✔ High-quality reagents help reduce risks from the start Follow us for more expert insights & don’t let contamination hold back your research! #CellCulture #Biotechnology #Mycoplasma #ContaminationControl #Immunology #ScientificResearch #LabTech #Antibiotics

  • 📢 We are happy to announce that we will be attending the 34th Annual Meeting of the Society for Virology (GfV). March 4th – 7th  📍 Hamburg, Germany Visit our booth to explore InvivoGen's extensive range of reagents, including our reporter cell lines, PRR ligands, inhibitors, mouse anti-mouse antibodies, and more. 🛠 We look forward to discussing your research and finding out how InvivoGen can support your scientific goals. 💡🥼 #GfVMeeting #Congress #Immunology #Virology #Invivostudies #Pathogens #Viruses #PRR #PAMP #ImmuneSensors #Science #Research #InvivoGen

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  • 🚀 New Product Launch from InvivoGen ! 🚀 We’re excited to introduce our latest anti-hIL-4Rα-derived biosimilar monoclonal antibody (mAb) that blocks both IL-4 and IL-13 signaling – now available in two isotypes to meet your research needs! ✨ IgG1 for high-effector functions (ADCC & CDC) ✨ IgG4 (S228P) for minimal immune activation These mAbs, based on the variable region of dupilumab, are ideal for immunology and therapeutic research and have been FDA-approved for the treatment of asthma, atopic dermatitis, and chronic sinusitis. 🥼✅ #InvivoGen #Biotech #MonoclonalAntibodies #Dupilumab #ImmunologyResearch #BiosimilarAntibodies #1190264-60-8

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  • 🧬 Screen. Profile. Discover. 🔬 InvivoGen’s PRR Compound Screening & Profiling Service is your shortcut to high-quality, reproducible results. Here’s why researchers trust our service: ✅ Fully Customizable – Tailor the screening to your research needs 🔍 ✅ Fast Turnaround – Get conclusive data in 4 weeks ⏳ ✅ Comprehensive Panels – TLRs, STING, RIG-I, NOD, CLRs & more! 🧪 ✅ Reliable & Confidential – Stringent quality control & secure data 🔐 With over 25 years of expertise, we help researchers accelerate drug discovery, vaccine development, and immunomodulator testing. Ready to screen your next breakthrough compound? Let’s discuss! 💬👇 #DrugDiscovery #LeadCompound #PRRScreening #Immunology #Biotech #InnateImmunity #VaccineDevelopment #MolecularBiology #TLRResearch #InvivoGen #LabTech

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    👉 Discover InvivoGen's recombinant B18R protein: a potent inhibitor of type I interferons (IFNs), acting as a decoy receptor to neutralize key immune signaling molecules. 🔑 B18R Advantages: •    Inhibition of Type I IFN Signaling: Effectively blocks IFN-mediated pathways, essential for studies on viral infections and immune responses. ✅ •    Enhanced mRNA Transfection Efficiency: Suppresses the antiviral state induced by IFNs, improving cell viability and increasing mRNA transfection efficiency, beneficial for RNA-mediated gene delivery and iPSC reprogramming. ✅ •    High Purity and Quality: Produced in CHO cells, ensuring proper protein glycosylation and 3D structure; each batch is ≥95% pure and free from bacterial contaminants. ✅ •    Broad Species Specificity: Inhibits IFNs from various species, including human, mouse, rabbit, pig, rat, and cow, providing versatility across different experimental models. ✅ •    Validated Biological Activity: Each lot undergoes rigorous functional testing to confirm efficacy in inhibiting IFN signaling, ensuring reliable performance in your experiments. ✅ Elevate your research with InvivoGen's B18R protein, designed to provide consistent and reproducible results in studies involving type I interferon pathways. #InvivoGen #B18R #InterferonInhibitor #Immunology #Science #Interferon #BiomedicalResearch #mRNA #Virology #Viralinfection #Transfection

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