Jali Medical, Inc.

Identifying novel biomarkers with TMS-EEG – Methodological possibilities and challenges TMS-EEG is an up-and-coming method for biomarker identification. In theory, the biomarkers can be obtained from any neocortical brain area. However, it might be challenging in practice, and we are still lacking evidence of this as most of the studies have been limited to a few cortical areas. TMS-EEG can potentially also identify biomarkers unattainable with other methods. This is because TMS can activate both the GABAergic inhibitory and glutamatergic excitatory systems, but differently, and these different activations can be recorded with EEG. TMS-EEG can also index distinct GABAA and GABAB physiologic activity based on the fact that these indices have different timescales that are consistent with their underlying neurotransmitter physiological properties. The TMS-EEG biomarker field is still somewhat limited as more work is needed to unravel some of the neural origins of measures and understand the interaction between neural signals and artifacts. Furthermore, most protocols have not been studied for their repeatability yet with TMS-EEG, and with many protocols, we may still need to optimize how to measure each protocol. Due to these issues that need to be addressed, most biomarker candidates are still in the development phase. DOI: https://lnkd.in/eWm-gD_Y Authors: Elisa Kallioniemi, Zafiris J. Daskalakis Read full article at: https://lnkd.in/ejbe7waZ #tms #eeg #emg #mep #GABA #biomarker #neurons #excitation #inhibition #closedloop #neurophysiology #electroencephalography #neurotransmitter  

World Mental Health Day, observed on October 10 annually, seeks to increase awareness and inspire action to assist people dealing with mental health issues. Emphasizing the need of establishing supportive, healthy work environments worldwide, the subject selected by the World Federation for Mental Health (WFMH) this year "Mental Health at Work." 💚🌎 Recognizing that a healthy workforce is essential to productivity and innovation, the United Nations and many other organizations dedicate October to supporting mental health and well-being for its staff. Reducing stress is only one aspect of mental health at work; another is building an inclusive environment where staff members feel appreciated, supported, and free to discuss their mental health. Read full article at: https://lnkd.in/e7m7vRvf Reference: https://lnkd.in/dqQJ8JnX #mentalhealth #tms #rTMS #OCD #addiction #FDACleared #depression #brainstimulation #brainscience 

Final day at the #Neuroscience Conference – don't leave without visiting Booth 280! We’ve got cutting-edge insights waiting for you. Hope to see you there! 🧠 #eeg #tms #closedloop #tDCS #emg #gait #vestibular #wearabletech #eyetracking #neuronavigation #brainresearch #sfn #sfn2024

Day 3 of the #Neuroscience Conference is in full gear! Don’t miss the chance to swing by Booth 280 to connect with our product specialists (Ali Jalinous, Jukka Kinnunen, Simo-Pekka Simonaho, Sameer Dhamne, Reza Jalinous). It’s the perfect way to fuel your day! 🧠 #eeg #tms #closedloop #tDCS #emg #gait #vestibular #wearabletech #eyetracking #neuronavigation #brainresearch #sfn #sfn2024

Day 2 at the #Neuroscience Conference (#sfn) is in full swing! Don’t forget to swing by Booth 280 – we’ve got exciting insights to share. Come chat with us (Ali Jalinous, Simo-Pekka Simonaho, Jukka Kinnunen, Sameer Dhamne), and let's connect! See you there! 🧠 #eeg #tms #closedloop #tDCS #emg #gait #vestibular #wearabletech #eyetracking #neuronavigation #brainresearch

See you at the SFN Booth #280 (Neuroscience Conference on Oct 6-8, McCormick Place, Chicago, IL) Our team of product specialists and innovators are prepared to offer valuable insights and expertise, whether it be by sharing the most recent advancements in neuroscience technology, exploring potential collaborative opportunities, or offering customized solutions to your specific research requirements. Jali Medical, Inc., Jaltron LLC, Bittium, Neursantys 🧠 You can visit https://lnkd.in/eJG_Pv4V for more details. #eeg #tms #tdcs #neuronavigation #eyetracking #tmseeg #brainstimulation #vestibular #gait #wearabletechnology #brainscience #neuromodulation #brainresearch #sfn

Pulsed inhibition of corticospinal excitability by the thalamocortical sleep spindle Authors: Umair Hassan, Prince Okyere, Milad Amini Masouleh, Christoph Zrenner, Ulf Ziemann, Til Ole Bergmann DOI: https://lnkd.in/eqCHT5Us Researchers (authors) provide the first in-human demonstration of the feasibility of real-time sleep spindle phase-triggered TMS and of a phasic modulation of corticospinal excitability by the sleep spindle. Our findings are best explained by sleep spindles exerting an asymmetrical “pulsed inhibition” on corticospinal excitability, complementing previous work demonstrating a phasic modulation of corticospinal excitability by the sleep SO (Bergmann et al. 2012) as well as asymmetrical “pulsed facilitation” by the sensorimotor mu-alpha rhythm during wakefulness (Bergmann et al. 2019; Zrenner et al. 2018). Utilizing this technique, future work should further characterize the excitation-inhibition profile of sleep spindles, investigate their interaction with SOs, and test their role as windows of phase-dependent synaptic plasticity as well as their causal relevance for memory reactivation in the context of systems memory consolidation. Read more at https://lnkd.in/ejbe7waZ #eeg #tms #sleepstudy #brainstimulation #brainresearch #neuromodulation #SFN #neuroscience #neuroplasticity #realtime #nrem #inhibition #excitation #sensorimotor #fMRI #neuronavigation

Jali Medical, Inc. will be exhibiting at Neuroscience (#SFN) 2024 from October 6-9! 🎉 Come visit us and connect with our team of innovators and product specialists who will be on hand to: ✅ Demo our cutting-edge products ✅ Answer all your questions ✅ Share experiences and insights ✅ Explore ideas for collaboration Don’t miss this opportunity to engage with the latest in neuroscience technology #Bittium, #Protxx, #Jaltron LLC, #Neursantys! We (Ali Jalinous, Reza Jalinous, Sameer Dhamne, Jukka Kinnunen and Simo-Pekka Simonaho look forward to seeing you there! #Neuroscience2024 #JaliMedical #Innovation #TMS #brainresearch #TMS #rTMS #eeg #closedloop #tDCS #biomarkers #neuromodulation #neuroscience #brainstimulation #neurophysiology #physicalmedicineandrehab #neurorehab #kinesiology #psychiatry #psychology #gait #verstibular #movementdisorder #mdd #depression #ocd #innovation #wearabledevices

Jali Medical: Premier Distributor of Advanced Neuroscience Technologies. Join us at the SFN Booth 280! Our product specialists and innovators are glad to meet with you, share insights, and discuss cooperation prospects specific to your research projects. Click https://lnkd.in/eJG_Pv4V for more information! See you there! 🧠 #TMS #rTMS #EEG #EMG #ECG #pneumaticstimulator #gait #vestibular #eyetracking #neuronavigation #brainstimulation #brainresearch #neuromodulation #neuroscience #noninvasive #closedloop #epilepsy #movementdisorder #motorcontrol #TBI #stroke #rehabilitation #kinesiology #psychiatry #realtimeEEG #PTSD #neuroplasticity #physicaltherapy #sportsmedicine #MEP #wearablesensor

Recent Development in TMS Therapy Systems with FDA Clearance Transcranial Magnetic Stimulation (TMS) has evolved significantly since its introduction, with multiple FDA clearances affirming its growing role in treating mental health conditions, especially major depressive disorder (MDD). These advancements are backed by robust clinical trials and real-world data that validate the efficacy, safety, and increasing versatility of TMS therapy. 1. Time-Efficient Treatment Protocols Recent FDA clearances have introduced time-efficient TMS protocols that significantly reduce the duration of individual sessions. Intermittent Theta Burst Stimulation (iTBS) has emerged as a notable innovation, with treatment times reduced from 30-40 minutes to just over three minutes per session. Research has confirmed that these shorter protocols maintain the effectiveness of traditional TMS therapy, making it more accessible for both patients and clinics. Read full article at: https://lnkd.in/eJQpyYaG #TMS #MDD #clinical #mentalhealth #ocd #addiction #psychiatrist #psychiatry #psychiatricnurse #neuroscience #depression #fdacleared #noninvasive #brainstimulation #brainresearch #neuronavigation #behavioralhealth #wellness #tmstherapy #brainscience #cognitivehealth #healthcare