Jali Medical, Inc.

Recent Development in TMS Therapy Systems with FDA Clearance Transcranial Magnetic Stimulation (TMS) has evolved significantly since its introduction, with multiple FDA clearances affirming its growing role in treating mental health conditions, especially major depressive disorder (MDD). These advancements are backed by robust clinical trials and real-world data that validate the efficacy, safety, and increasing versatility of TMS therapy. 1. Time-Efficient Treatment Protocols Recent FDA clearances have introduced time-efficient TMS protocols that significantly reduce the duration of individual sessions. Intermittent Theta Burst Stimulation (iTBS) has emerged as a notable innovation, with treatment times reduced from 30-40 minutes to just over three minutes per session. Research has confirmed that these shorter protocols maintain the effectiveness of traditional TMS therapy, making it more accessible for both patients and clinics. Read full article at: https://lnkd.in/eJQpyYaG #TMS #MDD #clinical #mentalhealth #ocd #addiction #psychiatrist #psychiatry #psychiatricnurse #neuroscience #depression #fdacleared #noninvasive #brainstimulation #brainresearch #neuronavigation #behavioralhealth #wellness #tmstherapy #brainscience #cognitivehealth #healthcare

Jali Medical: Premier Distributor of Advanced Neuroscience Technologies. Join us at the SFN Booth 280! Our product specialists and innovators are glad to meet with you, share insights, and discuss cooperation prospects specific to your research projects. Click https://lnkd.in/eJG_Pv4V for more information! See you there! 🧠 #TMS #rTMS #EEG #EMG #ECG #pneumaticstimulator #gait #vestibular #eyetracking #neuronavigation #brainstimulation #brainresearch #neuromodulation #neuroscience #noninvasive #closedloop #epilepsy #movementdisorder #motorcontrol #TBI #stroke #rehabilitation #kinesiology #psychiatry #realtimeEEG #PTSD #neuroplasticity #physicaltherapy #sportsmedicine #MEP #wearablesensor

Heart rate change as a predictor of treatment outcome for ring-coil accelerated low frequency repetitive transcranial magnetic stimulation in major depressive disorder: An exploratory study DOI: https://lnkd.in/e9BQAnxg Major depressive disorder (MDD) is now the foremost cause of disability worldwide (Friedrich, 2017). As a safe (Rossi et al., 2009) and effective (Brunoni et al., 2017; Lefaucheur et al., 2020; Milev et al., 2016) non-invasive clinical treatment for medication-resistant MDD, repetitive transcranial magnetic stimulation (rTMS) has entered increasingly widespread clinical use. Current objectives of translational rTMS research include the identification of reliable predictors of clinical response to rTMS prior to the start of a treatment course. Predictive biomarkers, if proven reliable, could help to identify likely rTMS responders and non-responders, and could also provide objective measures for monitoring engagement of target circuits during treatment. Read full article at: https://lnkd.in/ejbe7waZ #TMS #rTMS #EEG #ECG #EKG #MDD #depression #autism #noninvasive #behavioralhealth #mentalhealth #cardiac #aneurysm #dementia #multiplesclerosis #biomarkers #hypertension #stroke #psychiatricdisorder #parkinsons #huntingtons #TBI #cardiomyopathy #vasculardisease #dyslipidemia #psychotherapy

Neural encoding of saltatory pneumotactile velocity in human glabrous hand Authors: Hyuntaek Oh, Rebecca Custead, Yingying Wang, Steven Barlow Published: August 25, 2017 DOI: https://lnkd.in/dhnpVzAa The primary goal of the present study was to functionally map the human brain to identify the relation between saltatory pneumotactile stimulation at 3 velocities on the glabrous hand and the evoked hemodynamic BOLD response in select regions of interest (ROIs), including cerebral somatosensory areas (S1, S2, PPC, posterior insula), and deep cerebellum among 20 neurotypical adults using high-resolution fMRI methods..... Read full article at: https://lnkd.in/ejbe7waZ #tms #rTMS #eeg #MEG #fMRI #tbi #neuromodulation #neuronavigation #neuroimaging #neuroscience #neurophysiology #neuroplasticity #brainstimulation #corticalstimulation #somatosensory #brainscience #closedloop #noninvasive #stroke #electrophysiology #pneumatic #pneumotactile #orofacial #tactilestimulation

A simulation study: comparing independent component analysis and signal-space projection – source-informed reconstruction for rejecting muscle artifacts evoked by transcranial magnetic stimulation Authors: Tuomas Petteri Mutanen, corresponding author* Ida Ilmoniemi, Iiris Atti, Johanna Metsomaa, and Risto Juhani Ilmoniemi DOI: 10.3389/fnhum.2024.1324958 The combination of transcranial magnetic stimulation (TMS) and electroencephalography (EEG) allows researchers to explore cortico-cortical connections. To study effective connections, the first few tens of milliseconds of the TMS-evoked potentials are the most critical. Yet, TMS-evoked artifacts complicate the interpretation of early-latency data. Data-processing strategies like independent component analysis (ICA) and the combined signal-space projection–source-informed reconstruction approach (SSP–SIR) are designed to mitigate artifacts, but their objective assessment is challenging because the true neuronal EEG responses under large-amplitude artifacts are generally unknown. Through simulations, we quantified how the spatiotemporal properties of the artifacts affect the cleaning performances of ICA and SSP–SIR. Read full article at: https://lnkd.in/ejbe7waZ #tms #rTMS #eeg #emg #TEP #MEP #fMRI #tmscoil #neurons #neuromodulation #neuronavigation #nTMS #neuroscience #neurophysiology #neuroplasticity #brainstimulation #corticalstimulation #peripheralstimulation #auditorystimulation #somatosensory #brainsicence #closedloop #motorcontrol #motormovement #noninvasive #movementdisorder #electrophysiology

TMS combined with EEG: Recommendations and open issues for data collection and analysis Authors: Julio C. Hernandez-Pavon, Domenica Veniero, Til Ole Bergmann, et al DOI: https://lnkd.in/eQhN57an Transcranial magnetic stimulation (TMS) has proven to be an effective, non-invasive tool for probing the human brain. The first effort to combine TMS with electroencephalography (TMS−EEG) was reported in 1989 by Cracco and colleagues and later by Amassian and colleagues. However, the technique was not yet ready for broader use as the recorded cortical response was obscured by the TMS-induced electromagnetic artifact. A few years had to pass before the electromagnetic artifact problem was partially solved. In 1996, the first successful TMS−EEG study (published by Ilmoniemi et al., demonstrated the feasibility of the combination to record cortical excitability and connectivity. After these first successful recordings, the interest in using EEG to measure brain activation elicited by TMS has steadily increased. Read full article at: https://lnkd.in/ejbe7waZ #tms #rTMS #eeg #emg #TEP #MEP #fMRI #tmscoil #neurons #neuromodulation #neuronavigation #nTMS #neuroscience #neurophysiology #neuroplasticity #brainstimulation #corticalstimulation #peripheralstimulation #auditorystimulation #somatosensory #brainsicence #closedloop #motorcontrol #motormovement #noninvasive #movementdisorder #electrophysiology

From Lab to Clinic: The Transformative Power of Transcranial Magnetic Stimulation (TMS) in Neuroscience Transcranial Magnetic Stimulation (TMS) revolutionized neuroscience by bridging the gap between research and therapeutic application. This non-invasive brain stimulation approach modulates neuronal activity with magnetic fields, providing vital insights into brain function and therapeutic advantages for a wide range of neurological and psychiatric problems. This article explores the evolution of TMS from a research tool to a clinical stronghold, covering important discoveries and people that contributed to its development. Read full article at: https://lnkd.in/eS9japtC #tms #eeg #fmri #tDCS #tES #FDAapproved #neuronavigation #brainstimulation #noninvasive #tmstherapy #brainmapping #brainresearch #closedloop #motorcontrol #gait #vestibular #psychiatry #neurophysiology #neuroscience #neuromodulation #neuroplasticity #mdd #ocd #stroke #tbi #epilepsy #ptsd #multiplesclerosis #chronicpain

Brain Ultimate TMS System Showcased at Prestigious Beth Israel Deaconess Medical Center Course The Intensive Course in Transcranial Magnetic Stimulation (TMS) was held at the Berenson-Allen Center for Noninvasive Brain Stimulation at Beth Israel Deaconess Medical Center in Boston on July 15–19, 2024. On Tuesday, July 16, this event showcased state-of-the-art developments in TMS technology, such as the Brain Ultimate TMS System. With Brain Ultimate TMS, Yingchi Technology's FDA-approved Brain Ultimate TMS System is widely available in the United States. Jali Medical, which manages research applications, and Brain Ultimate US, which concentrates on therapeutic settings, are collaborating to promote the system. With its adaptable collaborative approach and modular configuration, this cutting-edge device significantly advances research in noninvasive brain stimulation while improving the effectiveness and accessibility of TMS therapies. Read the full event article at: https://lnkd.in/eKTJ8Gu5 ( ~ excerpt from https://lnkd.in/eDxa4RdC) #tms #eeg #dbs #FDAapproved #neuronavigation #brainstimulation #noninvasive #tmstherapy #brainmapping #brainresearch #closedloop #motorcontrol #gait #vestibular #psychiatry #neurophysiology #neuroscience #neuromodulation #epilepsy #alzheimer #parkinson #mdd

July in Neuroscience: Landmark Discoveries and Pioneering Advances July has witnessed pivotal moments in neuroscience, shaping our understanding of the brain. From the Hodgkin-Huxley model to the first deep brain stimulation for Parkinson's, these milestones have revolutionized neurology and paved the way for innovative treatments. Let's explore five significant discoveries that have illuminated the path of neurological research and treatment, including the cloning of Dolly the sheep. These discoveries have significantly advanced our understanding of the brain and its disorders. As we reflect on July's milestones in neuroscience, we recognize the researchers whose dedication continues to drive progress in understanding and treating brain-related diseases. Read full article at: https://lnkd.in/e-m34xft #tms #eeg #eeg #dbs #neuronavigation #brainstimulation #brainmapping #brainresearch #closedloop #motorcontrol #gait #vestibular #psychiatry #neurophysiology #neuroscience #neuromodulation #epilepsy #alzheimer #parkinson #dementia #biomarker #dolly #neuralcells #cloningtechniques #neurons #neurosurgery 

Deep brain stimulation for Parkinson's disease Parkinson's disease (PD) is the second most common neurodegenerative disorder. It is a progressive illness due to loss of dopaminergic neurons in the substantia nigra compacta (Fig. 1), and degeneration of its projections to the corpus striatum (nucleus caudatus and putamen) [1, 2]. The main motor symptoms of PD are tremors, rigidity, akinesia (both bradykinesia, i.e., slowness of movement, and hypokinesia, i.e., small amplitude of movement) and postural instability. These motor features can vary between patients, and also within the same patient during the course of the illness. Phenotypically, at any point in time, a PD patient can be classified as tremor dominant, rigid akinetic (often accompanied by postural instability and gait disorders) or so-called intermediary [3, 4]. Nonmotor symptoms of PD include constipation, depression, pain, sleep disorders, loss of sense of smell and, eventually, cognitive decline and autonomic dysfunction. There is no cure for PD. The hallmark of symptomatic treatment is levodopa, which is converted to dopamine in the brain. Read the full article at: https://lnkd.in/ejbe7waZ #tms #rTMS #eeg #tdcs #dbs #parkinson #parkinsonstreatment #ataxia #neuronavigation #cognitive #cognitivedecline #brainstimulation #deepbrainstimulation #tremors #brainresearch #pain #depression #neurophysiology #neuroscience #neuromodulation #motorcontrol #gait #vestibular #akinesia #dopamine #movementdisorders #closedloop