Maze Therapeutics

We are pleased to announce that the first participant has been dosed in our Phase 1 clinical trial evaluating MZE782. MZE782 is a potentially first-in-class, oral, small molecule targeting the solute transporter, SLC6A19, and has the potential to address chronic #kidneydisease (CKD) patients. Learn more about the MZE782 program here: https://lnkd.in/eYczrDPK

Karol Estrada, MSc, PhD and the entire Maze team welcomed back one of our scientific founders, Mark Daly, as part of our internal educational R&D seminar series. As a renowned geneticist and an influential figure in the field of human genetics, Mark discussed the history of #humangenetics and how it can further support our therapeutic development mission. This was especially inspiring for us as a team that is harnessing the power of genetics to transform the lives of patients. Thanks to Mark for his time and teachings. 

Karol Estrada, MSc, PhD and the entire Maze team welcomed back one of our scientific founders, Mark Daly, as part of our internal educational R&D seminar series. As a renowned geneticist and an influential figure in the field of human genetics, Mark discussed the history of #humangenetics and how it can further support our therapeutic development mission. This was especially inspiring for us as a team that is harnessing the power of genetics to transform the lives of patients. Thanks to Mark for his time and teachings. 

We had a great evening filled with team spirit and plenty of fun as we cheered on the Giants and enjoyed each other's company outside the office. Events like these are a great way to celebrate our achievements and strengthen the bonds that drive our collective success. Thank you to Mazers for making the game so special. Check out highlights from the outing below.

"There are always people who will give you reasons why you can’t do something…They’ll say it's too hard or it can’t be done. But that’s exactly why we should be working on it.” This is one of many inspiring quotes expressed by our Chairman and Co-founder Charles Homcy during his recent visit to our office. In celebration of our 5-year milestone as a company, Charles shared his background, career journey and what led him to Maze. We're thankful for his time and insights.

We're celebrating #NationalInternDay! Thank you to our interns for bringing curiosity, enthusiasm and great ideas to Maze. Your contributions have made a difference to our team, and we are excited to continue to watch you grow in your careers.

Please join us in welcoming Courtney Phillips to Maze as our General Counsel. Courtney is a seasoned legal and business executive with deep biopharmaceutical experience. We are excited to add her expertise to the Maze team and look forward to accomplishing big things together as we seek to leverage the power of human genetics to bring new precision medicines to patients with common diseases. 

This year is a significant one for us as we commemorate five years of Maze. In a short period of time, we're proud of the progress we've made within the common and rare disease communities with the help of our team members and valued partners. Our mission to translate #geneticinsights into groundbreaking therapies has never been stronger as we expand our clinical portfolio. As we celebrate this milestone, hear from our CEO Jason Coloma, Ph.D., Chairman of the Board and Third Rock Ventures partner Charles Homcy, M.D., and Board Member Sekar (Sek) Kathiresan, M.D., as they speak to our progress to date and vision for the future ahead.

In honor of #PrideMonth, Mazers came together for a happy hour in support of the LGBTQ+ community. At Maze, we believe that the best innovations come from a team that embraces diverse perspectives and experiences, and we're proud to have that culture and an environment where freedom of expression is welcomed and encouraged. Thank you to all Mazers for your yearlong support toward this aim.   

The National Kidney Foundation's Northern California Kidney Walk is one of our favorite events of the year! Not only do we get to come together as Team AMAZEing and make memories as an organization, but by participating in this walk, we are contributing directly to the #kidneydisease community. We are proud to have surpassed our fundraising goal this year to (1) ensure those living with chronic kidney disease get diagnosed, treated and supported early, (2) provide tools to help promote #kidneyhealth, and (3) help support life-saving research. Thanks to all Mazers for your participation and contributions.