Nanovaccine Institute

Nanovaccine Institute researchers envision a healthier world made possible by supersizing the potential of powerful particles. Get to know our work at Iowa State University and other collaborative institutions across Iowa and the US. https://lnkd.in/gqNbEiiV

NBC News: Bird flu cases in people quietly tick up, with dozens reported across 6 states "Dr. Richard Webby, director of the World Health Organization Collaborating Center for Studies on the Ecology of Influenza in Animals and Birds, said the Washington cases represented “more of the same” in a pattern observed across the U.S. as workers tasked with culling sick animals have fallen ill. However, one human case — in Missouri — has puzzled researchers and health officials, because that person did not have contact with animals. It is not clear how the person was exposed, and results of further tests that could offer clues are still pending, according to the CDC. Six health workers exposed to the patient reported respiratory symptoms. Webby said the virus’ spread in cows for the past 10 months has raised experts’ level of concern because cows are mammals and interact with humans frequently. That increases the likelihood the virus could mutate to pass from person to person." https://lnkd.in/g-cvnh4k

The new episode of the Nanovax Podcast is now available. This episode discusses the emergence and evolution of #AvianInfluenza with Kevin Legge https://lnkd.in/gZty_DQ4 #publichealth #vaccines #disease #influenza #nanoparticles #iowastate #iowa #research #innovation

🐣 New research on enhancing gut health in commercial poultry 🐥 Layer segmented filamentous bacteria colonize and impact gut health of broiler chickens Jared Meinen-Jochum, Caleb J. Skow, Melha Mellata l 2024 Host-Microbial Interactions The research explored whether introducing segmented filamentous bacteria (SFB) to newly hatched broilers could accelerate gut maturation and boost resistance to harmful bacteria. The results? Early colonization of SFB not only accelerated gut maturation but also enhanced the expression of key immune-related genes and reduced levels of Enterobacteriaceae—offering improved resistance to intestinal and extraintestinal pathogens. By better understanding gut immune development in food-producing animals, we can improve both animal welfare and human health. Learn more about how gut microbiota plays a crucial role in early life immunity in poultry! 🧬🐔 #AnimalHealth #GutMicrobiota #PoultryFarming #FoodSafety #Research https://lnkd.in/g9vKZw4e

📢New publication on influenza vaccination in older adults (≥65 years)! 🎉 Similar humoral responses but distinct CD4+ T cell transcriptomic profiles in older adults elicited by MF59 adjuvanted and high dose influenza vaccines Huy Quang Quach, Iana H. Haralambieva, Krista M. Goergen, Diane E. Grill, Jun Chen, Inna G. Ovsyannikova, Gregory A. Poland & Richard B. Kennedy l Scientific Reports volume 14, Article number: 24420 (2024) This study dives into the differences between two influenza vaccines—MF59-adjuvanted (MF59Flu) and high-dose (HDFlu)—and how they impact CD4+ T cell responses in older adults. Researchers analyzed transcriptomic profiles from 234 recipients and identified hundreds of differentially expressed genes (DEGs) in CD4+ T cells of older adults after receiving MF59Flu and HDFlu. While both vaccines triggered unique and shared gene expression changes, none of the DEGs were significantly correlated with influenza protection, underscoring the complexity of immune responses in this age group. This research highlights the need for further exploration into the factors driving immunity in older adults! 💡🦠 Read more about the findings and their implications for improving vaccine strategies for seniors. #Vaccines #Immunology #PublicHealth #Aging #Research https://lnkd.in/gW6szCSf

Submit your research to Nanovax 2025! The event will bring together experts from all corners of vaccine and therapeutic research to advance promising and robust next-generation nanovaccines and nanotherapeutics through regulatory approvals and to clinical trials. The program will emphasize a transdisciplinary approach to transform the design and manufacturing of nanovaccines and nanotherapeutics that integrates nanotechnology, materials science, immunology, oncology, neuroscience, microbiology, clinical science, and social science. Request for Presentation Abstracts – Due November 4, 2024, 5 PM Central Time https://lnkd.in/gcAaaDnA

Episode 3 of the Nanovax Podcast is now available. This episode discusses the emergence and evolution of avian H5N1. Our episode guest is Kevin Legge, Pathology Endowed Professor of Pulmonary Immunology Research, Vice Chair for Research in the Department of Pathology, Professor of Microbiology and Immunology, Director, Department of Pathology Research Flow Cytometry Facility, Director, Interdisciplinary Program in Immunology at the University of Iowa, and Associate Director at the Nanovaccine Institute. The information in this podcast is for educational purposes only and does not constitute medical advice or diagnosis. https://lnkd.in/gmt7wEHg

Nanovax 2025 will bring together experts from vaccine and therapeutic research to advance promising next-generation nanovaccines and nanotherapeutics. Programming will emphasize early career participation, mentorship, and high-impact research opportunities. Submit your research presentation by November 4th! Interested in sponsoring the event? Follow the link below to view opportunities. https://lnkd.in/gBjGufFW

Our congratulations to CBE faculty members Surya Mallapragada and Wenzhen Li, honored for patents received, at the ISU College of Engineering Honors and Awards Ceremony. They're shown with College of Engineering Dean W Samuel Easterling. Also recognized but not in attendance were faculty members Rizia Bardhan, Ratul Chowdhury and Derrick Rollins (retired). See the full list of college honorees: https://lnkd.in/gUHARQP6

The request for presentation and poster abstracts is now open for Nanovax 2025: Next Generation Countermeasures for Emerging and Re-Emerging Disease Dates: April 2-3, 2025 Location: Ames, Iowa The event will bring together experts from all corners of vaccine and therapeutic research to advance promising and robust next-generation nanovaccines and nanotherapeutics through regulatory approvals and to clinical trials. Abstract submission info here: https://lnkd.in/gBjGufFW Interested in sponsoring Nanovax 2025? See how at this link: https://lnkd.in/eihwR3nX