It's July 1, which means a new edition of #TheAxon is hot off the press! Check out what our team has been following this past month in neurology.
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Neurology Live is your trusted news source for breaking drug approvals, pipeline trials and emerging trends in neurology. The digital and print publication provides physicians and other healthcare professionals with up-to-date disease-specific news, clinical information and other resources that can help them provide better care to patients. At Neurology Live, you'll find in-depth conference coverage and information about upcoming meetings, content from our affiliated print journals, video interviews with leading physician experts and other multimedia resources. Get all the latest news on individual medical conditions in our condition centers: • Dementia & Alzheimer Disease • Epilepsy • Headache & Migraine • Movement Disorders • Multiple Sclerosis • Neuromuscular • Sleep Medicine • Stroke
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Updates
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In this episode, Emma Ciafaloni, MD, an expert on #Duchenne muscular dystrophy, reviewed standard-of-care treatment options and provided clinical insights on adverse effects and safety concerns, particularly with corticosteroids. University of Rochester Medical Center View: https://lnkd.in/ecA23Yr5
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In recent news, REGENXBIO Inc. has initiated enrollment in a new cohort of patients aged 1-3 in its phase 1/2 AFFINITY DUCHENNE trial to assess the safety and efficacy of RGX-202, an investigational gene therapy, in boys with #DMD. https://lnkd.in/ezW5EHQb
Phase 1/2 AFFINITY DUCHENNE Trial Expands to Include Younger Cohort of Duchenne Muscular Dystrophy
neurologylive.com
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A new study showed that 12-week supervised strength training program resulted in increased maximal hip and knee extension muscle strength, lowered apathy and anxiety, and induced muscle hypertrophy in women with myotonic dystrophy type 1. #DM1 University of Quebec https://lnkd.in/eZcpja5w
Strength Training Provides Several Noted Benefits to Women With Myotonic Dystrophy Type 1
neurologylive.com
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New 12-month data from the phase 2b PARADIGM study showed that treatment with investigational PrimeC (NeuroSense Therapeutics) resulted in a statistically significant improvement in disease progression and survival in patients with #ALS. https://lnkd.in/e-M8nMCu
12-Month PARADIGM Data Showcases PrimeC’s Ability to Extend Survival in ALS
neurologylive.com
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Luis Felipe Tornes, MD, of Baptist Health, discussed #migraine treatment as a whole throughout this point of history, including the ways we can optimize recently approved therapies and the approach to managing attacks. https://lnkd.in/ey4sE3RR
NeuroVoices: Luis Felipe Tornes, MD, on Optimizing Migraine Care and Reasons for Escalation
neurologylive.com
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In this episode, Donald Negroski, MD, provided commentary on a first of its kind study showing that health care-related social determinants of health may impact brain structure and aging in #MS. CMSC #CMSC2024 International Journal of MS Care (IJMSC) Watch Now: https://lnkd.in/evurb8F8
Impacts of Health Care-Related Social Determinants of Health
neurologylive.com
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New data from a phase 3 study of patients with #ParkinsonDisease showed that treatment with investigational was safe and well tolerated, with noted improvements in motor and non-motor activities, as well as cognitive function. Annovis Bio, Inc. https://lnkd.in/etc7anxw
Buntanetap Improves Motor, Non-Motor and Cognitive Symptoms of Parkinson Disease in Phase 3 Study
neurologylive.com
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🧠 It's #BrainGames time! Test your neurology knowledge with NeurologyLive®'s weekly quiz series. This week's questions include the theme of #migraine/nerve decompression surgery. 🤕 🎮 Play the quiz here: https://lnkd.in/eRPyecXR
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Positive results from the phase 1b/2a SELECT-HD trial assessing WVE-003 (Wave Life Sciences), an investigational first-in-class, allele-selective antisense oligonucleotide for Huntington disease, showed a significant reduction in mutant huntingtin protein and preserved healthy protein huntingtin protein in patients with HD, with no serious adverse events. https://lnkd.in/eb-taUTZ
WVE-003 Shows Allele-Selective Mutant Huntingtin Reduction in Phase 1b/2a SELECT-HD Trial
neurologylive.com