PFI

PFI

Biotechnology Research

Burlingame, California 1,163 followers

Organoid Discovery Engine - The Future of 3D Cell-based Assays

About us

Protein Fluidics is commercializing biological assay automation platforms using our novel microfluidic technologies to accelerate data driven decisions. The Pu·MA System 3D for your 3D cell models, organoids or spheroids, maintains the cells in our specially designed flowchips to allow for easy media, metabolite or reagent exchanges for your oncology, toxicity or metabolomics research. At the core of the Pu·MA System is our patented Valve-less Fluidic Switching (VLFS) which enables precision transfer of reagents through flowchips without the use of integrated valves or pumps. We are passionate about providing scientists with the latest technologies to help them create the next generation of therapeutic and diagnostic tests. The company is privately held and located in the San Francisco Bay Area.

Industry
Biotechnology Research
Company size
2-10 employees
Headquarters
Burlingame, California
Type
Privately Held
Founded
2015
Specialties
Automated organoid assay, 3D Cell-based assay, microfluidics, flowchip, organoid assay, compatible with hydrogel, open platform, organoid, and organoid profiling

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Updates

  • View organization page for PFI, graphic

    1,163 followers

    Don’t miss out on this amazing deal!

    View organization page for PFI, graphic

    1,163 followers

    🚨 Take advantage of our End of Year Discount and get up to 20% off on automating your 3D cell model-based assay research!    Streamlining your workflow with the Pu·MA System can:  🙌 Reduce hands-on pipetting by 20X  🧪Save precious samples and reagents  🔬 Make imaging a breeze  ➕ And much more!    Schedule a meeting to claim your discount TODAY! Full details at https://lnkd.in/gD3y5_DD #3Dcellassay #flowchips #pumasystem

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  • PFI reposted this

    View profile for Evan Cromwell, graphic

    Founder of Protein Fluidics and Seasoned Entrepreneur | Focused on simplifying the lab to improve productivity.

    It was great to see everyone back at LRIG again. The talks were very interesting and use of ML is getting very sophisticated.

    View profile for Michael Biros, graphic

    Cellerynt Group Marketing Automation Services

    Our LRIG Bay Area event “Integrating informatics, automation and machine learning for smarter labs” had a terrific set of speakers today from BigHat Biosciences, insitro, Iambic Therapeutics, Multiply Labs, IDEAYA Biosciences, Utiliware and Monomer Bio. Jimmy Sastra’s coda put it nicely -Biotech is becoming “Techbio” as many companies ride the confluence of advances in biology, the proliferation of automation and the effectiveness of ML. 

    • SRO at today's LRIG Bay Area
    • Jimmy Sastra - CEO and Co-founder at Monomer Bio
  • View organization page for PFI, graphic

    1,163 followers

    🚨 Take advantage of our End of Year Discount and get up to 20% off on automating your 3D cell model-based assay research!    Streamlining your workflow with the Pu·MA System can:  🙌 Reduce hands-on pipetting by 20X  🧪Save precious samples and reagents  🔬 Make imaging a breeze  ➕ And much more!    Schedule a meeting to claim your discount TODAY! Full details at https://lnkd.in/gD3y5_DD #3Dcellassay #flowchips #pumasystem

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  • View organization page for PFI, graphic

    1,163 followers

    🎀 Breast Cancer Awareness Month starts today, and we reflect on the impact breast cancer has had on our personal and professional lives.     By creating tools for #innovative and streamlined research, we hope to enable groundbreaking discoveries by the researchers who work tirelessly on understanding the disease.👩🔬   🔬 This 4IC tumoroid was stained with Hoechst, Phalloidin, and Vimentin. Immunofluorescence staining is an essential technique in #biomarker elucidation, and leads to a better comprehension of potential treatment pathways for breast cancer. Learn more: https://lnkd.in/gDWSmRgZ   #BreastCancerAwarenessMonth #BreastCancerResearch 

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  • View organization page for PFI, graphic

    1,163 followers

    Epidermal growth factor receptor (EGFR) signaling pathway is an essential mechanism for the cell cycle. Mutations of the EGFR protein can lead to uninhibited cell growth, division, and spread of cancerous cells.  In collaboration with MatTek Life Sciences and SCIENION, we treated HTC116 colon #cancer cells with human recombinant epidermal growth factor (EGF) and/or Cetuximab using an #automated workflow. After treatment, EGFR internalization analysis was done using CellPathfinder (Yokogawa Life Science).   The analysis showed that, when activated with EGF, EGFR localization moved from the cell's membrane to its cytoplasm. However, when treated with Cetuximab before the introduction of EGF, the internalization of EGFR was impeded. This is consistent with Cetuximab binding to EGFR and interfering with EGF activation. Further studies are on-going with patient-derived CRC cancer models.    Download the full poster: https://lnkd.in/gSe22pwc   

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  • View organization page for PFI, graphic

    1,163 followers

     #ThrowbackThursday to our SLAS 2022 poster: Dynamic multifunctional profiling of 3D cell models with an #automated microfluidic-based assay system. In collaboration with Matt Burow’s group at Tulane University, Oksana Sirenko, and her team at Molecular Devices, Inc, we showcased how the Pu·MA System 3D enables:  👩🔬 automated drug treatment of patient-derived #tumoroids to study drug response  📈 multifunctional profiling with metabolite analysis  🔬 high content imaging of tumoroids within the #flowchips    Download the full poster now!  https://lnkd.in/gzyHPkcA 

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