Phronetik®

Researchers at the Centre for Genomic Regulation (CRG) have created the first blueprint of the human spliceosome, the complex molecular machine that edits genetic messages transcribed from DNA, allowing cells to create different versions of a protein from a single gene.

Patients with overproduction of protein from the chromodomain helicase DNA binding (CHD2) gene can develop a very rare and severe neurodevelopmental disorder with profound implications for their quality of life.

The vehicles that deliver gene editing cargo to the body’s cells can be toxic, complicating gene therapies, particularly those addressed to brain cells of developing fetuses.

In humans, hundreds of proteins interact in a complex network dubbed the interactome.

In the Great Hall of the Cunard Building, deep in Lower Manhattan, members of the Cancer Research Institute (CRI), a nonprofit that supports the discovery and development of cancer immunotherapies, gathered for their 2024 Annual Awards Gala.

Neural stem cells (NSCs) are important for the development and regeneration of the nervous system.

A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall into one of four categories.

Let’s GEAUX to #ACRP2025 in The Big Easy, where you’ll find gold-standard education, expertise & insights to support your professional development, and a commitment to quality & integrity in the #ClinicalResearch process. Explore the schedule at 2025.acrpnet.org/schedule. Video clips credit: LeBron Joseph Music: Trombone Shorty “Tripped Out Slim” #Phronetik #ClinicalResearch

A new study by researchers at the VIB-UGent Center for Medical Biotechnology and collaborators demonstrates how a protein linked to the human immune system lures and traps HIV-1 and herpes simplex virus-1.

An international research team has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin—DNA and proteins—plays a critical role.