Quantitative Biosciences Institute, UCSF

QBI has launched the Research and Engineering to Accelerate Discovery (READY) Center, led by Dr. Lee Spraggon, PhD and QBI Director Dr. Nevan Krogan. This biomedical center merges academic and industry expertise to unravel disease biology and speed up therapeutic development. Using innovative genome engineering, including CRISPR, the READY Center will build a comprehensive map of human protein interactions in infectious diseases, cancer, and neurological disorders. The center is also collaborating with the University of California, San Francisco Department of Psychiatry on a $13.7M CIRM-funded project led by QBI Investigator Dr. Tomasz Jan Nowakowski. This initiative aims to advance schizophrenia research by exploring its molecular foundations and potential therapeutic targets. Learn more: https://lnkd.in/ge9zaSeN

QBI is looking for an experienced Financial Services Analyst who will be responsible for a broad spectrum of professional accounting services that support the department. Accounting activities include allocation of expenses by account, monitoring of and reporting on expenses for the department accounts, executing and monitoring recharge activities, purchasing and fiscal year closing activities. The incumbent is responsible for developing, modifying as needed, and controlling all accounting processes, analyzes project costs, monitoring all department funds for lapsing and overdrafts, and providing ad hoc expense reports. The position will be responsible for the interpretation and proper implementation of UC policy and procedures relative to account management and purchasing. View the job posting and apply: https://lnkd.in/gvgUDp6M

Hosted by Lee Spraggon, PhD, QBI and the READY Center are presenting a seminar with Dr. Daniel Paull, Senior Vice President of Discovery & Platform Development at The New York Stem Cell Foundation Research Institute on October 15 at UCSF Mission Bay. Cell biology is at an intersection where, to generate datasets capable of being applicable to tools such as machine learning, an increase in experimental scale is required. Over the past decade, Dr. Paull and his group have worked to develop and optimize a platform, the NYSCF Global Stem Cell Array, capable of deriving, gene editing, and differentiating induced pluripotent stem cells (iPSCs). This talk will focus on the development of this platform, its use in disease modeling and its application at the intersection of biology and AI. Learn more & register! https://lnkd.in/d9mj8JeK

Join us on September 30 for a seminar with Dr. Celeste Karch, Professor of Psychiatry at Washington University School of Medicine in St. Louis, hosted by Danielle Swaney. Dr. Karch's talk will explore how rare and common genetic variants contribute to microglia dysfunction in Alzheimer’s and related dementias. Don’t miss it! Learn more: https://lnkd.in/gC8eQgh7

QBI and Bruker are excited to present a special lunch and learn session featuring Dr. Nathanael Gray from Stanford University at the Bruker Center of Excellence in Proteomics at the University of California, San Francisco, moderated by Robyn Kaake & Alicia Richards on October 2, 2024 at 12 PM. Dr. Gray, the Krishnan-Shah Family Professor of Chemical and Systems Biology at Stanford, is a leader in cancer drug discovery. His research uses the tools of synthetic chemistry, protein biochemistry, and cancer biology to discover and validate new strategies for addressing anti-cancer targets. His work has had broad impact in the areas of kinase inhibitor and degrader design and in circumventing drug resistance. For more event details & registration, visit https://lnkd.in/g56jVbGa.

Save the date! Co-organized by Drs. Nevan Krogan, Brian Shoichet & Molly Shoichet, QBI and PRiME Next-Generation Precision Medicine at the University of Toronto are co-hosting a symposium at the University of California, San Francisco on November 8, 2024 to unite experts in exploring new paths to therapeutics via drug discovery, personalized medicine, AI, and quantitative biology. The goal is to foster collaboration—join us! Registration is open: https://lnkd.in/da6Pby4w

Join us for a seminar with Professor Clare Jolly university from University College Dublin, on the topic of "Permissivity and Reprogramming During HIV-1 Infection of T Cells" at 11:00 AM on September 11 at Gladstone Institutes. Dr. Jolly's talk will focus on her group’s most recent discoveries about how HIV-1 hijacks T cell signalling pathways and reprograms resting T-cells to license infection, and the consequences this has for T cell biology, viral persistence and pathogenesis. Learn more & register: https://lnkd.in/gWnETkvi

Dr. Lise Musset, Head of the Parasitology Laboratory at Institut Pasteur de la Guyane, will be presenting a seminar at QBI UCSF on September 5th. Her talk, "Challenges for Malaria Elimination in the Guiana Shield," will provide an in-depth look at the epidemiology of malaria in the region and her team’s innovative approaches to overcoming this global health challenge. Learn more & register to join: https://lnkd.in/gnSSxH7j

QBI is thrilled to present a seminar featuring Dr. Vicky Sanz Moreno, Professor at the Breast Cancer Now Toby Robins Research Centre at The Institute of Cancer Research, hosted by Natalia Jura. In her talk titled "Organelles Take Centre Stage: Secretory, Nuclear and Mitochondrial Dynamics in Metastatic Cancer Cells," Dr. Sanz-Moreno will highlight how cancer cells adjust their movement and internal structures to spread throughout the body, responding to signals from their surrounding environment. Join us on September 4 at 11 AM at UCSF Mission Bay. Learn more & register: https://lnkd.in/g7kkwEEm

We're thrilled to invite you to the 2024 "QBI Internship Symposium" on August 15 from 1:00-4:30 pm at UCSF's Byers Auditorium in Genentech Hall. This event is a fantastic opportunity to hear from our talented interns as they share their unique paths to science and present their internship projects spanning diverse areas of basic and discovery research. Each intern will deliver a 10-minute talk, offering insights into their research and experiences. The symposium will conclude with a reception. Join us for a chance to connect and celebrate these emerging scientists. We hope to see you there! Learn more: https://lnkd.in/gh9QMXdA #QBIInternshipSymposium