RheumNow

Exploring severe active cases of granulomatosis with polyangiitis (GPA) & microscopic polyangiitis (MPA). Two physician case reports offer critical insights. Sponsored by Amgen.

Fasenra approved in the EU for eosinophilic granulomatosis with polyangiitis

🔉 🔉 RA Risk Radar 🔉🔉 Patients with RA may have higher risk of heart disease, infection, and malignancy. Listen as Dr. Jeffery Curtis and Dr. Jon Giles discuss how to assess and manage these risks in the clinic. Sponsored by AbbVie US Medical Affairs.

Study of 168 patients with MDA5-positive Dermatomyositis finds that elevated IL-6 (≥ 13.41pg/m), lymphopenia (< 0.5 × 109) older age and high LDH predicted 6-month all-cause mortality in DM

STAR study shows 102 RA pts in LDA > 3 mos & pred 5 mg/d did equally well with either prednisone taper or changing to hydrocortisone 20 mg/d and taperin HC. At 12 mos both wer able to D/C GC (55% HC vs 47% pred tapering; p=0.4).

Surprise! Low-level proteinuria is more associated w/ proliferative LN and adverse long-term outcomes. Study of 249 SLE GN pts (median 33 yrs; proteinuria =2.2/D; 71% proliferative (PGN) - 60% PGN w ≤1 g/d proteinuria (more renal recovery) - 79% w/ 1-3g/d - 71% w/ ≥3 g/d (worst outcomes)

Granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA): severe active cases reported. Key takeaways from two physician case reports. Sponsored by Amgen.

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Blue Collar Arthritis (10.25.2024) Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow.

Psoriasis pts w/ Arthralgia referred for Rheum Eval - 1419 referred pts, 8.4% (119) met at risk for PsA criteria, and 29% (35) developed PsA w/in 1yr. Predictors included +FHx PsO, Ultrasound synovitis or enthesopathy findings, & low tender joint count.