San Diego Biomedical Research Institute

San Diego BioMed would like to officially unveil our stunning new artwork by local artist and friend, Aaron Cover with Coverworks. Aaron calls this mural “Stranding Together,” and dedicates this piece to his family. Aaron’s inspiration draws from parametric art and the double helix structure of DNA, but with his added personal flair and reflection on modern society. We are very grateful to Aaron and all his hard work to create a lasting piece of art that livens up our space and inspires the daily research here at San Diego BioMed!

I would like to share with you that I’ve just completed six months of research at San Diego Biomedical Research Institute in collaboration with Gilbert's lab. I am grateful to my PI, Prof. Batsheva Kerem, for her continuous support throughout this experience. I am also thankful to Prof. David Gilbert and Dr. Takayo Sasaki for their valuable impact on my learning process. Special thanks to the Hebrew University’s Diversity Unit and Prof. Mona Khoury for the financial support that made this research possible. I’m now back at The Hebrew University of Jerusalem, ready to apply what I’ve learned to my genome instability and cancer research.

Last week, San Diego BioMed proudly held a celebratory reception to mark a milestone moment: our 10-year anniversary! Surrounded by cherished collaborators, former colleagues, and beloved friends and family, we reflected on a decade of remarkable achievements made possible by our exceptional team. As we gathered in this joyous atmosphere, familiar faces from our journey came together, each of whom has played a vital role in our success. We extend our heartfelt gratitude to everyone who joined us in this celebration and to those who will continue to stand by us as we embrace many more prosperous decades of San Diego BioMed! #10year #celebration #anniversary #reception #sandiegobiomed

Help us welcome back San Diego Biomedical Research Institute (San Diego BioMed), which returned for an investment from Mission Driven Finance®’s statewide strategy Advance California. 𝐖𝐇𝐀𝐓 𝐓𝐇𝐄𝐘 𝐃𝐎 🧪 San Diego Biomedical Research Institute (San Diego BioMed) and its president Joanna Davies, Ph.D., are dedicated to supporting biomedical research that focuses on predicting and preventing diseases such as cancer, diabetes, and HIV. The nonprofit attracts scientific talent from around the world, creating high-skill, high-wage jobs in the San Diego area and providing investigators with access to space for both targeted research and collaboration with peers. With 24 full-time staff members, San Diego BioMed generates revenue primarily through research grants from organizations like the National Institute of Health (NIH) and foundations including the American Diabetes Association. 𝐖𝐇𝐘 𝐖𝐄 𝐈𝐍𝐕𝐄𝐒𝐓𝐄𝐃 💰 San Diego BioMed’s strategic plan includes enhancing its financial sustainability by increasing scale and targeting philanthropic support. In July, San Diego BioMed returned for a second investment, seeking working capital to fund cash flow for seven new NIH grants. #impactinvesting #impinv #smallbusinesslending #smallbizloans

This week, San Diego BioMed would like to shout out many thanks to our recent guest speaker, Elena Blanco-Suarez. Dr. Blanco-Suarez presented a fascinating seminar titled, “Astrocyte-mediated neuroplasticity: A target for stroke recovery.” In Dr. Blanco-Suarez’s words, “We are currently developing new methods to manipulate Chrdl1 and other astrocytic proteins to promote neuroprotection and recovery from stroke using genetic and proteomic tools and pharmacological approaches. Our studies underscore the heterogeneous time- and region-dependent astrocyte functions under pathological conditions.” As our saying goes, we at San Diego BioMed strive to give every patient a fighting chance and we love to extend our science in focus seminars to those with like minds. We wish you greatness in your endeavors Dr. Blanco-Suarez! #sandiegobiomed #seminar #research #stroke 

San Diego BioMed is on a roll, as we excitingly congratulate another published paper from our team – the Baccala Lab. Join us in many congratulations to our own Roberto Baccala and Rosana Gonzalez, in collaboration with the Catz laboratory at Scripps. In a short summary, Dr. Baccala describes the detection of nucleic acids by endosomal Toll-like receptors (TLRs) as not only a critical event in the initiation of innate immune responses to infections, but also in the induction of lupus and other autoimmune diseases. This study identified Rab27a, a small GTPase, as a novel regulator of endosomal TLR responses. It was found that Rab27a deficiency impairs the internalization of nucleic acids, the intracellular trafficking of TLRs, TLR signaling, and the production and secretion of effector cytokines including type I interferon and IL-10 in neutrophils and plasmacytoid dendritic cells.     Read the article at https://lnkd.in/guEJfBnh Read and learn more about the Baccala Lab at https://lnkd.in/griNkZHT #research #sandiegobiomed #lupus #autoimmune

Last week, San Diego BioMed had the pleasure of hosting guest speaker Ashley Buckle. Thank you so much Ashley for sharing your great insights with the team in one of our Science in Focus Seminars! With a talk titled, "Structure of an autoantigen-autoantibody complex provides a new structural rationalization for three decades of immunological data," Dr. Buckle describes in his own words the use of "a combination of structural, biophysical and computational techniques to investigate a long-standing problem in structural immunology – what are the structural determinants of autoantigenicity?” Here at San Diego BioMed, we foster a culture of endless learning opportunities. We hope to continue bringing in new ideas and talks for our next page of the Science in Focus Seminar Series!

San Diego BioMed is excited to announce a successful paper and, most importantly, the very first for our own -- The Murin Lab. This is only the first step of many as San Diego BioMed seeks to continue to grow and create differences in our communities. Congratulations for completing this fantastic and impactful work detailing the spatial location of CD16a within the NK cell ADCC immune synapse using MINFLUX nanoscopy. Read and learn more below! https://lnkd.in/gUKSsRjh

Congratulations, James and the Binley Lab here at San Diego BioMed for their latest publication. Read and learn more below!

San Diego BioMed would like to congratulate our own—the Marcondes Lab—on the publication of their latest research paper titled, “On the issue of treating HIV in people with syndemic mental-health and substance-use disorders.” We celebrate their impactful research as a testament to their collaboration, dedication, and hard work. The article discusses the potential benefits of long-acting antiretroviral therapy (ART) for people living with HIV (PWH) who also have substance-use and mental-health disorders. It highlights that these individuals are often excluded from clinical trials, despite facing significant challenges in adhering to daily oral ART. Including them in trials could provide insights into the clinical value of long-acting therapies, especially in addressing adherence issues and the complex interactions between HIV, mental health, and substance use. Read and learn more at https://lnkd.in/gGyRfZfS #research #sandiegobiomed #hiv #art #substanceuse #mentalhealth