Symeres

Join the Symeres team at the 26th North American ISSX and 39th JSSX Meeting in Hawaii! Rory Curtis, Vice President of Business Development at Symeres, and Leah Haydock, Director of Business Development at Admescope (a Symeres company), will be delighted to discuss how we can support your discovery programs. Curious about our comprehensive pre-clinical ADME-tox capabilities for small molecules, ADCs, oligonucleotides, peptides, and more? Reach out to us via LinkedIn to book an appointment in advance, or stop by our booth 111. Don't miss our poster presentation on "Analytical Methods for PK Analysis of ADCs." We're happy to discuss and assist you with any questions you may have! #Symeres #Admescope #DMPK #PharmaceuticalDevelopment #ADMETox #DrugDiscovery

Symeres is pleased to announce that Chris Teleha, Paul O'Shea, and Dimitriy V. will participate in ChemOutsourcing, the largest USA-based API and Pharmaceutical Ingredients show.   This prestigious event, held in September 3-6 (Parsippany Hilton, Parsippany, NJ), attracts 700-800 customers and executives from the pharmaceutical, biotech, chemical, and chemistry services industries worldwide. ChemOutsourcing focuses on the entire API development supply chain, spanning raw materials, drug discovery, process and chemical development, analytical QA/QC, intermediates, and commercial manufacturing of both branded and generic small molecule APIs.   Attendees include executive buyers and customers from pharmaceutical companies and consultancies, experienced in sourcing starting materials, intermediates, and active ingredients. The show features 130+ exhibitors and is known for its accessible buyers, evening networking events, and upscale seaside venue, providing ample opportunities for high-level networking and business development.   We look forward to engaging with the community and exploring the latest advancements in our field.   Join us at this event by visiting our booth #29! If you have any questions, do not hesitate to ask Chris Teleha or Paul O'Shea by sending them a PM in advance!   #ChemOutsourcing #Symeres #Pharmaceuticals #API #DrugDiscovery #Networking #PharmaIndustry

We are excited to announce that Russell Thomas, Sascha Hartmann, and Laszlo Szilagyi will represent Symeres at the XXVIII EFMC International Symposium on Medicinal Chemistry in Rome, Italy, from September 1-5, 2024.   This is a key event in the medicinal chemistry and drug discovery calendar, attracting around 1,000 participants from both industry and academia.   The EFMC-ISMC 2024 will feature plenary sessions with lectures by renowned experts like Prof. David MacMillan (Princeton University), Prof. Véronique Gouverneur (University of Oxford), and Dr. Emma R Parmee (The Janssen Pharmaceutical Companies of Johnson & Johnson). The programme includes the presentation of several prestigious awards and covers themes such as Chemical Biology, Drug Discovery Projects, and Technologies, along with special sessions on topics like Early Career Women in Medicinal Chemistry.   We look forward to engaging with the community and exploring the latest advancements in our field.   Join us at this event by visiting our booth #54!   #MedicinalChemistry #DrugDiscovery #EFMCISMC2024 #Symeres #Pharmaceuticals #ScientificConference

A family of solute carriers (SLC) is an important group of membrane transporters involved in drug absorption, distribution and elimination. Regulatory authorities (EMA, FDA) recommend investigating the potential roles of SLC superfamily members OATP1B1, OATP1B3, OAT1, OAT3, OCT2, MATE1 and MATE2 for transporter-mediated drug-drug interactions (DDI), by evaluating whether the new drug candidate is a substrate (potential DDI victim) or an inhibitor (potential DDI perpetrator) towards drug transporters. In addition, EMA suggests also considering investigation of OCT1, whenever in vitro and in vivo findings suggest its involvement in DDI to be anticipated. Learn more via this post and the Admescope website. #Symeres #Admescope #Transporters #DrugDiscovery #DrugDevelopment

Route design  •  IND/IMPD support  •  Phase-fit process optimization  •  Final form research and selection  •  Drug Substance Manufacture  •  Drug Product Manufacture At Symeres, we provide an integrated approach to Drug Substance and Drug Product development, ensuring comprehensive control and scalable, safe chemistry for manufacturing. Our development strategy delivers manufacturing routes that meet both operational and regulatory requirements. With distinct non-GMP and cGMP business units, we help you achieve key preclinical milestones quickly and efficiently seamlessly transitioning into GMP operations for clinical manufacturing, supported by our experienced team and dedicated project manager. Trust Symeres for a cost-effective, streamlined, and expert-driven process from start to finish. Click on the link below to learn more about our Drug Development service: https://lnkd.in/etW2mZp5 #CRO #Symeres #CMC #DrugDevelopment #ProcessResearch

While we still have several weeks of sunshine ahead this summer, Symeres is getting ready for a busy season of upcoming events upcoming fall! You can find a complete list of our upcoming events here: https://lnkd.in/e8StqmwS   Interested in meeting us locally to learn more or discuss how our expert teams comprised of 500+ experienced chemists located within Europe/the USA can help you achieve your goals with our own custom synthesis?   📅 Save the dates!   XXVIII EFMC International Symposium on Medicinal Chemistry (with Axxam) Sept 1-5th | Rome, Italy Booth #54   ChemOutsourcing 2024 Sept 3-6th | Parsippany, NJ USA Booth #29   Discovery on Target, Boston 2024 Sep 30th - Oct 3rd | Boston, MA USA Booth #408   ELRIG 2024 (with Axxam) Oct 2-3rd | London, UK Booth #C25   The Symeres team looks forward to seeing you there!   #symeres #events #conferences #lifesciences #chemistry #hitfind #leadoptimization #hittolead #organicsynthesis #preclinical #cro #custommolecules

#SymeresPolls   Olefin metathesis holds a special place in organic synthesis. Undoubtedly, the Grubbs catalyst is the most famous. However, there are other metals that can perform olefin metathesis as well.   Our team of over 500 chemists, including catalyst screening experts, can help you perform or optimize the olefin metathesis reaction and more. Contact us if you are interested in exploring a potential collaboration: https://lnkd.in/daJEr7Dq The correct answer is in the comments below 😉

The era of biocatalysis has arrived – are you ready to lead the way? Biocatalysis is defined as the use of enzymes to catalyze chemical reactions. The use of biocatalysts in the pharmaceutical industry is rapidly growing thanks to their exquisite chemo- regio- and enantioselectivity in chemical transformations. At Symeres we have experience with a broad number of enzymes: Lipases, esterases, proteases, ketoreductases, imine reductases, transaminases, ene-reductases, nitrile hydratases, nitrilases, racemases, peroxidases, Baeyer-Villiger mono-oxygenases, glycosyl hydrolases, glycosyl transferases, cytochrome p450, and carboxylic acid reductase enzymes. Learn more via: https://lnkd.in/eQDdz8Ud #Symeres #CRO #DrugDiscovery #MedicinalChemistry #Biocatalysis #Enzymes #Innovation

Curious about our state-of-the-art DMPK facilities? Watch this short clip from our Head of Business Development, Russell Thomas. Interested in discussing a project? Reach out to us through the Symeres website. #Symeres #CRO #DMPK #ADMETox #DrugDiscovery #DrugDevelopment

Experience over 30 years of synthetic expertise with Symeres. Specializing in synthetic chemistry, complex custom synthesis is in our DNA. While our synthetic services primarily focus on drug discovery, we also perform custom synthesis for diagnostics, agrochemicals, veterinary health, and electronics. With labs in the Netherlands and the USA, Symeres offers reliable and innovative solutions for all your synthetic chemistry needs including: Photochemistry  https://lnkd.in/esbYbgzf Biocatalysis  https://lnkd.in/eQDdz8Ud Chiral chemistry  https://lnkd.in/en8D5yRv Chemocatalysis https://lnkd.in/dS6ekV8U Flow chemistry  https://lnkd.in/ehWx-min Electrochemistry  https://lnkd.in/eDwUJwEd And many more… Partner with us for precision and quality in every project! https://lnkd.in/eWW622q2