The Paul G. Allen Frontiers Group

Microorganisms are the most abundant organisms on Earth, and how they react to climate change could impact life as we know it. We’re partnering with National Science Foundation (NSF) to support research into how the microbiome responds to climate change. Proposals due 1/23/25. 🔗 https://lnkd.in/g2CzzKfH

🐙 Octopus 🐙 arms can accomplish extraordinary tasks like using tools, opening jars and can even initiate a response without consulting the brain. SFSU research funded by the Allen Institute is starting to help solve the mysteries of these arms. https://bit.ly/3C47yxg

Biology Assistant Professor Robyn Crook’s Allen Institute-funded project is starting to help understand the neuroscience mysteries of octopus arms. These arms can accomplish extraordinary tasks like using tools, opening jars and initiating responses without consulting the brain. Understanding how they do this at a cellular level has been difficult due to technological limitations and expense of research. https://lnkd.in/gJT59Chu

"Octopus arms may literally have a mind of their own. Each limb contains its own version of a spinal cord, called an axial nerve cord, and these cords collectively harbor most of the animal’s neurons." The Transmitter's Calli McMurray explores the #FrontierScience of cephalopod nervous systems with Allen Distinguished Investigator Robyn Crook.

Illuminating the body's guards 🛡️🔦 Allen Distinguished Investigators Jennifer Prescher, Michelle Digman, and team have unveiled a new technique that uses bioluminescence to spotlight macrophages. 🔗 https://lnkd.in/gyTHeC9Q #FrontierScience | UC Irvine Department of Chemistry | UCI Samueli School of Engineering

Allen Distinguished Investigator Ami Bhatt and team have developed PhaVa - a tool to identify DNA inversions in bacteria. The tool has already led to discovery of a novel class of inversions found entirely within genes. More at Nature Press: https://lnkd.in/gQPPft-6 #FrontierScience

New insights into #schizophrenia are out today in Science suggesting that somatic mutations during neurogenesis might contribute to determining overall risk of developing SZ later in life. This work was supported, in part, through the Allen Discovery Center program. #FrontierScience #WorldMentalHealthDay

Congratulations to Allen Distinguished Investigator Bilal Sheikh, Ph.D., for selection as a Henriette-Herz Scout by the Alexander von Humboldt Foundation. This award allows him to nominate and mentor international postdoctoral researchers for the Humboldt Research Fellowship. #FrontierScience https://lnkd.in/d6JpYeyb

BIG NEWS! The Allen Discovery Center for Neuroimmune Interactions has partnered with Cell Press to hold the 4th Cell Symposia: The Neuro-Immune Axis in New York City at the The New York Academy of Medicine on September 7-9, 2025 with a special theme 'Charting the Periphery'. This will be the highest profile conference on #peripheral #neuroimmunology to date with keynote speakers 2021 The Nobel Prize recipient David Julius and Salk Institute for Biological Studies Nomis Center Director Susan Kaech. Other speakers include the following luminaries: Isaac Chiu Ana Domingos Henrique Veiga-Fernandes ANANDA GOLDRATH Ruaidhrí Jackson Jonathan Kipnis Vijay Kuchroo Rohini Kuner Qiufu Ma Kara Marshall Ruslan Medzhitov Daniel Mucida Francesca Odoardi Meenakshi Rao Asya Rolls Xin Sun Peng Xi Sebastien Talbot Kevin J. Tracey Shannon Turley We invite abstract submissions for short talks and posters. We are anticipating a big turnout as this will be the first time ever that Cell Symposia descends upon New York City. Peripheral neuroimmunology is reshaping how we view human health and disease. Even diseases that never considered the neuro-immune axis like cancer, are now invoking this paradigm shift to #neuroimmunology. Emerging and future therapeutics will find breakthroughs in this area. Major pharmaceutical companies are now building new divisions in #neuroinflammation. This is THE symposium to attend to learn about the latest and greatest that is happening in this explosive new field. I want to thank my co-lead David Artis Weill Cornell Medicine and our co-organizers and leading editors Kavitha Scranton and Benedicte Babayan for the many months of work to get this going. Thank you to Icahn School of Medicine at Mount Sinai for supporting our Allen Discovery Center for Neuroimmune Interactions. Thanks to Cell Press and Elsevier for allowing us to put this together. Finally, thanks to The Paul G. Allen Frontiers Group Paul G. Allen Family Foundation for supporting our center and vision to catalyze #peripheral #neuroimmunology into the mainstream of #biology #medicine #therapeutics.

Congrats to the Allen Discovery Center for Neuroimmune Interactions and Cell Press!