xcellbio

🚨 Publication Alert: Swiss scientists grow lungs from human foreskin fibroblasts! Researchers from the University of Bern used the AVATAR Odyssey to generate complex multicellular lung organoids from induced pluripotent stem cells. Congratulations to Vedat Burak Ozan and the entire lab of Thomas Geiser for their publication in Stem Cell Reviews and Reports! Read the publication here: https://lnkd.in/gEaTq_Ns To learn more about the world’s most advanced incubator, visit us at xcellbio.com/avatar #organoids #avatarodyssey #enhancepotency #cellandgenetherapy #tumormicroenvironment #celltherapymanufacturing

The AVATAR platform ensures that your cell therapy candidates can effortlessly scale from research to the clinic. Visit us at xcellbio.com to learn more. #curecancer #avatarfoundry #enhancepotency #cellandgenetherapy #tumormicroenvironment #celltherapymanufacturing

How do we test for cell therapy potency? We challenge them repeatedly against tumor cells until they get exhausted. Here, we demonstrate that CD19 CAR T cells manufactured with the AVATAR Foundry don't exhibit any exhaustion, remaining potent even after five tumor challenges. Visit us at xcellbio.com/gmp to learn how we manufacture more potent cell therapies #curecancer #avatarfoundry #enhancepotency #cellandgenetherapy #tumormicroenvironment #celltherapymanufacturing

Glucose transporter 1 (GLUT1) overexpression has been in the news by Crystal Mackall (https://lnkd.in/eFFb74Wp) and Michel Sadelain (https://lnkd.in/eZ4fN9ya). This has shown to increase #potency and #persistence by altering the cells metabolic pathways. Did you know that a simple method to increase GLUT1 expression for #cellandgenetherapy is altering the cell culture environment (mimicking #TME)? It also increases their persistent tumor killing capacity (https://lnkd.in/esAiqeV4). xcellbio bioreactor and Cytek Biosciences spectral FC analysis.

Working in cell therapy manufacturing? Start with the AVATAR Odyssey, our novel incubator for small-scale process development. Customizable oxygen and pressure levels allow you to identify the best manufacturing conditions for each cell therapy and improve potency and persistence through metabolic conditioning. Once the process has been optimized, you can transfer it easily to our GMP-compliant AVATAR Foundry for therapeutic manufacturing at scale. Currently in beta access, the Foundry will be released commercially next year. We will prioritize placements to teams already using the Odyssey system to build a complete workflow from process development to manufacturing. Learn more about the AVATAR Odyssey system at https://lnkd.in/eBtWYZz2. #celltherapy #biotechnology #gmp #celltherapymanufacturing

xcellbio's very own, James Lim, is featured in The Medicine Maker's 10-year anniversary addition. James gives his take on what the #pharma and #biopharma industries could look like in the future alongside Takeda's CSO, Chris Arendt, Miriam Monge, Head of Marketing Strategy & Customer Advocacy at Sartorius, Monika Paule, CEO of Caszyme, Sarah Browne, VP of Clinical Development at Altimmune, Inc., Anthony Lakavage, Senior Vice President for Global External Affairs at US Pharmacopeia, Chelsea Pratt, BioPharma Segment Marketing Manager at Bio-Rad Laboratories,  Claes Gustafsson, CCO at ATUM,  Anshul Gupte Ph.D. RAC Drugs, Vice President of Pharmaceutical Development at PCI Pharma Services, and Christine Marsh, Senior Vice President of Value and Access at Boehringer Ingelheim. Together these #ThoughtLeaders of the #biotech and #pharmacuticalindustry share insights into the changes we could see from #industrydisrupters in the coming years. To see this addition's whole segment, check out   https://lnkd.in/gPKiMw5k . Check out James' thoughts on beating #solidtumors with #celltherapy on pages 14 & 15.

Good morning from the Mesa! The xcellbio team arrives today in Phoenix for the #MeetingontheMesa #CellandGeneTherapyConference2024! We're so excited to have the opportunity to connect with researchers and colleagues from across the nation. #cellandgenetherapy #carttherapy #biotech

The xcellbio team has been prepping for the annual #CellAndGene #MeetingontheMesa. Hard to believe it's already only a week away! Brian, James and Vince can't wait for the opportunity to meet with everyone. Will you also be attending? Reach out to us or comment below! #cellandgenetherapy #CellTherapy #GeneTherapy #AVATARSystem #carttherapy #cellandgenemanufacturing #biotech

SFBN Feed: Xcell Biosciences Expands AmplifyBio Collaboration with Unique Cell and Gene Therapy Manufacturing Capabilities https://lnkd.in/gE7SHauZ SAN FRANCISCO–(BUSINESS WIRE)–Xcell Biosciences Inc. (Xcellbio), an instrumentation company focused on cell and gene therapy applications, today announced that it has expanded its collaboration with AmplifyBio, a rapidly growing contract development and manufacturing organization, through [...] #BayArea #SanFrancisco #Biotech #Lifescience #News

xcellbio's AVATAR™ Odyssey system and their latest AVATAR™ Foundry system deliver novel capabilities for improving the potency of cell and gene therapies by replicating the native tumor microenvironment. Details to set up an evaluation at your site: https://lnkd.in/gm5i8DGb #cellandgenetherapies #drugdiscovery https://lnkd.in/gp69_B82