Associate Scientist, Formulation

Associate Scientist, Formulation - Watertown, MA

Position Summary

Our novel ultra-long acting oral drug delivery platform uniquely combines three key elements: 1) controlled drug delivery from polymeric matrices, 2) traditional and nontraditional formulation processes, and 3) dynamic structural features providing gastric residence. As such, the individual in this role will be part of an interdisciplinary team supporting pre-clinical and clinical programs through product design, research, and development. Specifically, the Formulation Development group uses theoretical principles of chemistry, materials science, and engineering coupled with chemical and physical assays to define and characterize the drug delivery components of the oral dosage forms with the highest level of rigor and quality. Additionally, we aid the process development and clinical manufacturing operations for these compositions. Clear communication/documentation, strong attention to detail, and competency in the design, execution, analysis, and progression of experiments are expected. Innovation and team collaboration are essential. Strong grounding in chemistry or materials science is valuable. This Associate position will be reporting to a Scientist or Director within the Formulation Development group.

Role and Responsibilities (include, but are not limited to):

• Plan and execute experiments using pharmaceutical sciences and engineering techniques

• Design formulations for long acting gastric release

• Produce polymeric matrices using processes such as hot melt extrusion, film deposition, spray coating, and spray drying

• Characterize formulations for chemical, physical, processing, and stability attributes

• Apply chemical and mechanical principles to investigate and optimize formulations

• Work closely with engineering, process, and analytical teams

• Communicate findings internally

• Written: clear plans and reports for R&D programs

• In small groups: productive and collaborative discussions

• Department- and company-wide: focused presentations

• Be accountable for, and complete and accurate with data, communication, and timelines

• Help discover and develop novel approaches to control drug release and gastric residence

Key Qualifications

• B.A., B.Sc., or M.S. with 2+ years laboratory experience

• Degree in Chemistry, Chemical Engineering, Bio/Biomedical engineering, Materials Science, or related field

• Flexible, detailed, and careful bench scientist

• Knowledge of drug development, pharmacology, CMC, or regulatory a plus

• Demonstrated ability to work independently, following protocols without supervision

• Independently troubleshoot and deliver results with minimal direction

• Prioritize, plan, and organize work to meet deadlines and evolving priorities

• Exceptional written and oral communication skills which support an eagerness to engage colleagues, learn quickly, and grow