Garuda Therapeutics is pioneering the development of off-the-shelf hematopoietic stem cell (HSC)-based cellular therapies for treating patients with blood, bone marrow, immune, and metabolic disorders. The company uses state-of-the-art technologies in developmental biology, gene-editing, stem cells, and mechanobiology to engineer safe, compatible HSCs in scalable quantities to transform the lives of patients in need of an HSC-transplant.
Key Responsibilities:
Lead the development and qualification of diverse cellular assays, including ELISA (Enzyme-Linked Immunosorbent Assay) and ddPCR (droplet digital PCR), to characterize and release human pluripotent and hematopoietic stem cells
Execute in vitro assays to support process development activities and ensure the quality of cellular products
Collaborate closely with cross-functional teams within Garuda Therapeutics, providing technical expertise and guidance
Oversee the technical transfer and implementation of key assays across teams, ensuring consistency and reliability
Actively contribute to the authoring of technical documents supporting regulatory submissions, such as IND/CTA filings
Required Qualifications:
PhD in a relevant scientific discipline with 3-5+ years of related experience, or MS with 7-10+ years of related experience, or BS with 10+ years of related experience
Strong expertise in cell culture techniques and developing/qualifying cell-based assays, including ELISA and ddPCR methods
Proficiency in data analysis and interpretation, particularly in the context of molecular and cellular assays
Experience transferring assays to contract testing labs and ensuring their robustness and reproducibility
Demonstrated excellence in experimental design, execution, and analysis
Ability to think critically, troubleshoot effectively, and propose innovative solutions to assay challenges
Excellent organizational skills, attention to detail, and meticulous record-keeping
Outstanding written and verbal communication skills, with the ability to articulate complex scientific concepts effectively
Flexibility and adaptability to manage multiple projects simultaneously and collaborate in a fast-paced team environment
Highly self-motivated with a commitment to excellence and the flexibility to accommodate occasional weekend work if necessary
Preferred Qualifications:
Experience with additional analytical techniques relevant to cellular characterization, such as flow cytometry or qPCR
Hands-on experience in induced pluripotent stem cell (iPSC) culture maintenance, differentiation protocols, and hematopoietic stem cell (HSC) culture
Previous experience in designing, optimizing, and validating assays for the characterization of stem cell-derived products
Knowledge of Good Manufacturing Practices (GMP) and regulatory requirements for analytical methods in cell therapy product development
Powered by JazzHR
VEe8xwT6pX
Seniority level
Mid-Senior level
Employment type
Full-time
Job function
Research, Analyst, and Information Technology
Industries
Internet Publishing
Referrals increase your chances of interviewing at Garuda Therapeutics by 2x