Scientist I, Bioanalytical

Your experience includes… 

• PhD + 0-2 years or MS + 6 years of industry experience in Chemistry or related discipline e.g., biochemistry, biotechnology or pharmaceutical science. Post-doc experience a plus.
• In-depth scientific knowledge and hands on technical expertise on LC-MS, LC-MS/MS, and chromatography methodologies and instrumentation.
• Experience in high resolution mass spectrometric bioanalysis of oligonucleotides.
• Ability to work in a team orientated environment and conduct multiple laboratory and project tasks efficiently.
• RNA extraction from in vivo samples such as blood or tissue and downstream statistical bioinformatics analyses (not required experience, but a plus!).
  
  

You are interested in… 

• Developing LC-MS methods for characterization and quantitation of oligonucleotides in various biological matrices including biofluids, tissues, cells, and subcellular fractions.
• Conducting metabolite identification experiments, analyzing, and interpreting data to understand oligonucleotide metabolism.
• Designing and executing experiments from sample preparation, LC-MS/MS operation to data analysis & interpretation.
• Coordinating method transfer to CRO and serving as technical expert for method trouble shooting.
• Writing method protocols and sample analysis procedures. Preparing bioanalytical, metabolite identification reports and data presentations.
• Providing maintenance, quality control and troubleshooting of high-resolution mass spectrometer and UPLC systems.
  
  

About you: 

You are a scientist who is interested in developing and employing LC-MS methods to characterize and quantitate oligonucleotides. Your background may combine RNA therapeutics with biochemistry methods, LC-MS and proteomics or large molecule bioanalyses. You may also have experience in method qualification and bioanalyses to support pre-clinical studies from experience working with small molecule LC-MS and bioanalyses for small molecule drugs. You have excellent communication skills and can work in a dynamic and fast-paced work environment to support research, non-clinical and clinical development programs for various therapeutic indications.

Tessera employees are creative and collaborative problem solvers. They have a strong sense of integrity and unwavering commitment to scientific excellence. 

Meet your Manager:

All inquiries regarding the posted position should be directed to the Talent Partner (see below). Interested individuals must apply directly to be considered for the opening.

Jicheng Duan – Associate Director, DMPK

Jicheng Duan is a highly motivated scientist with deep expertise in LC-MS-based proteomic and bioanalytical development across diverse therapeutic areas, from early discovery to clinical development. At Tessera Therapeutics, he leads a team dedicated to advancing LC-MS-based proteomics and RNA bioanalysis to support preclinical studies for Gene Writing and Rewriting Therapeutics. Jicheng holds a PhD in Analytical Chemistry and has worked with prominent institutions and biopharmaceutical companies, including the University of California, Pacific Northwest National Laboratory, Bioverativ, and Sanofi. His work continues to drive innovation in therapeutic research and biotechnology.

Meet our Leadership Team and Board of Directors 

 

Meet your Talent Partner:

Narissa Furtado-Cordeiro - Manager, Talent Acquisition

Narissa joined the Biotechnology industry shortly after graduating with her BS in Marketing from Franklin Pierce University. She is currently pursuing a MS in Legal Studies from Northeastern University School of Law while working full time as a Manager in Talent Acquisition at Tessera. She is passionate about helping individuals find a fulfilling opportunity while considering their interests, aspirations and technical skills. Narissa lives in Northern Vermont and enjoys spending time outdoors with her husband, three-year-old daughter and German Shepherd.

Tessera offers a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits currently include group medical, vision and dental coverage, group life and disability insurance, 401(k) with company contribution, tuition reimbursement, and much more.

Company Summary:

Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.

More about Tessera Therapeutics:

Tessera is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, marital status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. Tessera provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with Tessera regarding a reasonable accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied, please contact the recruiter or Accommodations@tesseratx.com

Recruitment & Staffing Agencies: Tessera Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Tessera Therapeutics or its employees is strictly prohibited unless contacted directly by Tessera Therapeutics’ internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Tessera Therapeutics, and Tessera Therapeutics will not owe any referral or other fees with respect thereto.