Senior Scientist

Company Overview

Outer Biosciences' mission is to improve human skin health by discovering and developing novel bioactives that are more effective and safer than anything available today. Founded by a scientific team with deep experience in engineering advanced organ systems, our fully-integrated technology platform combines complex, long-lasting, clinically-relevant ex vivo skin models with multimodal data analysis and predictive machine learning. Brief company overview here.

Role Overview

Outer Biosciences is seeking a Senior Scientist who can play an important role in discovering novel bioactives and advancing our skin biology platform. This individual will bring a deep technical expertise on skin cell/tissue culture, compound screening, and comprehensive assays to evaluate the efficacy and toxicity of compounds. The successful candidate will work in a collaborative, fast-paced environment, contributing to our mission of revolutionizing skin health. This person will report to the Head of Skin Biology.

Key Responsibilities

• Lead the design and execution of bioactive screening experiments to assess efficacy and safety for next-generation bioactive discovery focusing on anti-aging and improving skin health.
• Perform model validation and characterization experiments using established bioactive materials/products and environmental stressors to induce various skin conditions.
• Integrate advanced technologies (e.g., 3D/Bio-printing, 3D cell culture, dynamic culture) to enhance the physiological relevance and sensitivity of bio models.
• Conduct multi-modal and comprehensive bioassays using various laboratory techniques (e.g. biochemical assays, omics analysis, histology and immunostaining, microscope, data analysis, etc).
• Serve as a subject matter expert on skin functions, skin cell culture, and readouts specific to measuring various skin functions.
• Establish and manage project goals, study plans, timelines, and deliverables, and ensure thorough record keeping and documentation.
• Mentor junior members providing scientific and technical guidance.
• Communicate plans, progress, and challenges across the organization and to leadership, proactively troubleshooting as needed.
• Build and maintain strong relationships and collaborations with external researchers, as applicable.
• Collaborate and support all Outer Biosciences teams in a fast-paced dynamic environment.
  
  

Qualifications

• MSc or PhD in Skin Biology, Dermatology, Pharmaceutical science, Bioengineering, Cosmetic science, or a related discipline with a focus on skin-related research; MSc with 3+ relevant experience, PhD with 0+ relevant experience. Appointment level will depend on skill set and experience.
• Extensive hands-on laboratory experience with skin cell/tissue-based models, including 2D, 3D, organoids, co-culture, and/or organ-chip technology, proficient in various biochemical/ELISA assays, staining techniques, imaging-based analysis, and gene/protein expression analysis.
• Strong ability to troubleshoot problems and provide effective solutions.
• Driven by curiosity and impact and thrives in a continuous learning environment.
• Excellent time management and prioritization skills, capable of managing multiple complex tasks simultaneously.
• Strong written, verbal, and interactive communication skills.
• Strong teamwork and collaboration skills with the ability to work effectively both independently and in a group.
  
  

We are deeply committed to diversity, equality, and inclusion in all its forms and practices. As a company we promote inclusion and desire to work with people from all walks of life. As we grow our team, we strive to be the change we want to see. If your experience is somewhat different from what we've described and you believe you can bring value and contribute in the role, we'd be honored to learn more about you.