Abhishesh Acharya, CPA’s Post

Proteins can be described as brilliant chemical tools. They are generally built from 20 amino acids that can be combined in endless ways. Using the information stored in DNA as a blueprint, the amino acids are linked together in our cells to form long strings. Then the magic of proteins happens: the string of amino acids twists and folds into a distinct – sometimes unique – three-dimensional structure. This structure is what gives proteins their function. Some become chemical building blocks that can create muscles, horns or feathers, while others may become hormones or antibodies. Many of them form enzymes, which drive life’s chemical reactions with astounding precision. The proteins that sit on the surfaces of cells are also important, and function as communication channels between the cell and its surroundings. It is hardly possible to overstate the potential encompassed by life’s chemical building blocks, these 20 amino acids. The Nobel Prize in Chemistry 2024 is about understanding and mastering them at an entirely new level. One half of the prize goes to Demis Hassabis and John Jumper, who have utilised artificial intelligence to successfully solve a problem that chemists wrestled with for over 50 years: predicting the three-dimensional structure of a protein from a sequence of amino acids. This has allowed them to predict the structure of almost all 200 million known proteins. The other half of the prize is awarded to David Baker. He has developed computerised methods for achieving what many people believed was impossible: creating proteins that did not previously exist and which, in many cases, have entirely new functions. The 2024 #NobelPrize in Chemistry has been awarded with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.” Learn more Press release: https://bit.ly/3TM8oVs Popular information: https://bit.ly/3XYHZGp Advanced information: https://bit.ly/4ewMBta

LTV: The Silent Threat in CRE Finance

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Quarterly, we do a deep dive analysis of the Flex/Light Industrial properties market for our current and target Southeast markets. ----- Reviewed Metric ------ Average Rent/SF (Flex Industrial) ----- Observation ------ The data reveals a strong upward trend in flex industrial rents across southeastern markets, driven by robust demand, even as other major commercial real estate sectors face slowdown or stagnation. However, direct market comparisons are less insightful due to varying lease structures (e.g., NNN, MG, FS) across regions, which can skew base rent figures and complicate cross-market analysis. #FlexIndustrial #SoutheastRealEstate #MarketAnalysis #CommercialRealEstate

Lifting heavy weights could be an underrated factor in business growth. An entrepreneur tracked the growth of companies with CEOs that lifted weights or did fight sports compared to the S&P500. He found this “deadlift ETF” fund outperformed the S&P500 by 140%, or 2.4 times over the last four years. https://trib.al/FK82oPN

Quarterly, we do a deep dive analysis of the Flex/Light Industrial properties market for our current and target Southeast markets. ----- Reviewed Metric ------ Cap Rate (Flex Industrial) ----- Observation ------ As expected, the larger the MSA, the less the cap rate expansion. Secondary and tertiary markets experienced the highest cap rate expansion. However, in recent years, transaction volume has been notably low and included many related-party and unique deals. While these can skew certain metrics, the overall trend remains largely accurate. #FlexIndustrial #SoutheastRealEstate #MarketAnalysis #CommercialRealEstate

Quarterly, we do a deep dive analysis of the Flex/Light Industrial properties market for our current and target Southeast markets. ----- Reviewed Metric ------ Year-over-Year Rent Growth (Overall Industrial) ----- Observation ------ The Southeast industrial real estate market is healing after an unprecedented demand surge in recent years. However, year-over-year rent growth figures related to the Flex/Light Industrial submarket require careful interpretation. This segment, which constitutes only 2-10% of total industrial square footage in any market, shows much stronger rent growth when analyzed in isolation. The overall industrial rent growth figures can obscure the true performance of Flex/Light Industrial properties due to the outsized influence of larger non-flex industrial square footage, which tends to dominate the aggregate data. #Flexindustrial #Southeast #Industrialrealestate